Corticosteroid

This page covers all Corticosteroid drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Glucocorticoid receptor, Androgen receptor, Glucocorticoid receptor, Mineralocorticoid receptor, Glucocorticoid receptor, Histamine H1 receptor, Muscarinic acetylcholine receptor M1.

Targets

Glucocorticoid receptor · Androgen receptor, Glucocorticoid receptor, Mineralocorticoid receptor · Glucocorticoid receptor, Histamine H1 receptor, Muscarinic acetylcholine receptor M1 · Progesterone receptor · Probable G-protein coupled receptor 97 · glucocorticoid receptor · Corticosteroid-binding globulin · Glucocorticoid receptor (GR) · melanocortin receptors

Marketed (98)

• Arnuity Ellipta · Haleon Us Holdings · Respiratory · 3100
• Cutivate · Teva Pharm · Oncology · 69.0
• Steroid injections · Sutherland Medical Center · Rheumatology, Orthopedics, Pain Management
  Steroid injections deliver corticosteroids directly to inflamed tissues to suppress local immune responses and reduce inflammation.
• Dermatop · Bausch Health · Oncology
• Steroid Drug · Services Hospital, Lahore · Immunology, Rheumatology, Endocrinology
  Steroids suppress the immune system and reduce inflammation by binding to glucocorticoid receptors and inhibiting pro-inflammatory cytokine production.
• Dexamethasone Ophthalmic Insert · The Cleveland Clinic · Ophthalmology
  Dexamethasone is a corticosteroid that suppresses inflammatory and immune responses in the eye by binding to glucocorticoid receptors.
• Solu-Medrol · Pfizer · Immunology
• CSs · Hoffmann-La Roche · Immunology / Inflammation
  CSs likely refers to corticosteroids, which suppress immune and inflammatory responses by binding to glucocorticoid receptors and inhibiting pro-inflammatory cytokine production.
• Triamcinolone 0.1% · Johns Hopkins University · Dermatology, Immunology
  Triamcinolone is a synthetic corticosteroid that suppresses inflammatory and immune responses by binding to glucocorticoid receptors and inhibiting pro-inflammatory cytokine production.
• Inhaled corticosteroid (ICS) · DARTNet Institute · Respiratory / Pulmonology
  Inhaled corticosteroids reduce airway inflammation by binding to glucocorticoid receptors in lung tissue, suppressing inflammatory cytokine production and immune cell activation.
• NAs · Beijing 302 Hospital · Respiratory
  Nasacort is a corticosteroid that works by reducing inflammation in the nasal passages.
• Rodinolone · Oncology
• Pred · Qilu Hospital of Shandong University · Immunology, Rheumatology, Endocrinology
  Pred is a corticosteroid that suppresses immune and inflammatory responses by binding to glucocorticoid receptors.
• Celestone Soluspan · Oncology
• Fml · AbbVie · Immunology
• Aclovate · Oncology
• Westcort · Sun Pharma · Immunology
• Lotemax · Bausch Health · Immunology
• Dexamethasone Sodium Phosphate · Merck & Co. · Immunology
• Joint injection with triamcinolone hexacetonide · Federal University of São Paulo · Rheumatology/Orthopedics
  Triamcinolone hexacetonide is a long-acting corticosteroid that suppresses local inflammation and immune responses when injected directly into a joint.
• Oral steroid - predonisolone · Instituto do Cancer do Estado de São Paulo · Oncology, Immunology
  Prednisolone is a corticosteroid that suppresses the immune system and reduces inflammation by binding to glucocorticoid receptors and inhibiting pro-inflammatory cytokine production.
• Celestone Soluspan · Merck & Co. · Immunology
• Low Dose Corticosteroids · Rutgers, The State University of New Jersey · Immunology, Rheumatology, Inflammatory diseases
  Low-dose corticosteroids suppress immune and inflammatory responses by binding glucocorticoid receptors and inhibiting pro-inflammatory cytokine production.
• Gluteus triamcinolone · Hospital de Braga · Immunology, Rheumatology, Dermatology
  Triamcinolone is a synthetic corticosteroid that suppresses inflammatory and immune responses by binding to glucocorticoid receptors and inhibiting pro-inflammatory cytokine production.
• infiltration of corticosteroids · Centre Hospitalier Departemental Vendee · Immunology, Rheumatology, Dermatology
  Corticosteroid infiltration delivers anti-inflammatory glucocorticoids directly into affected tissues to suppress local immune responses and reduce inflammation.
• Betametasone · Oncology
  Betamethasone works by binding to the glucocorticoid receptor, which then triggers a series of downstream effects that reduce inflammation and suppress the immune system.
• Elocon · Merck & Co. · Oncology
  Elocon works by binding to the progesterone receptor, which reduces inflammation and immune response in the body.
• Low dose budesonide rectal foam · Bausch Health Americas, Inc. · Gastroenterology
  Budesonide is a corticosteroid that suppresses local inflammation in the colon and rectum by binding to glucocorticoid receptors and inhibiting pro-inflammatory cytokine production.
• Betamethasone 17-Benzoate · Oncology
• COP · Acrotech Biopharma Inc. · Respiratory
  COP is a corticosteroid that reduces inflammation and swelling in the body.
• Corticosteroid (CS) · AbbVie · Immunology, Rheumatology, Endocrinology
  Corticosteroids suppress the immune system and reduce inflammation by binding to glucocorticoid receptors and inhibiting pro-inflammatory cytokine production.
• corticoid (altim® 1.5 ml) · Nantes University Hospital · Immunology / Inflammation
  Corticosteroids suppress immune and inflammatory responses by binding to glucocorticoid receptors and inhibiting pro-inflammatory cytokine production.
• blind injection of Triamcinolone · Complejo Hospitalario Universitario de Granada · Rheumatology / Orthopedics / Immunology
  Triamcinolone is a synthetic corticosteroid that suppresses inflammatory and immune responses by binding to glucocorticoid receptors.
• Kenalog Injectable Product · Hospital for Special Surgery, New York · Rheumatology, Orthopedics, Immunology
  Kenalog (triamcinolone acetonide) is a corticosteroid that suppresses inflammatory and immune responses by binding to glucocorticoid receptors.
• Steroid - Triamcinolone Acetonide · University of Missouri-Columbia · Immunology, Dermatology, Rheumatology
  Triamcinolone acetonide is a synthetic corticosteroid that suppresses the immune system and reduces inflammation by binding to glucocorticoid receptors.
• Triamcinolone acetonide injection · Somdech Phra Nangchao Sirikit Hospital · Immunology, Rheumatology, Dermatology
  Triamcinolone acetonide is a synthetic corticosteroid that suppresses the immune system and reduces inflammation by binding to glucocorticoid receptors.
• low-dose dexamethasone · Celgene · Immunology
  Low-dose dexamethasone is a corticosteroid that suppresses the immune system and reduces inflammation by binding to glucocorticoid receptors.
• fluocinolone acetonide intraocular implant · JHSPH Center for Clinical Trials · Ophthalmology
  Fluocinolone acetonide is a corticosteroid that suppresses inflammatory and immune responses in the eye when delivered directly via intraocular implant.
• High dose budesonide rectal foam · Bausch Health Americas, Inc. · Gastroenterology / Immunology
  Budesonide is a corticosteroid that suppresses local inflammation in the colon and rectum by binding to glucocorticoid receptors and inhibiting pro-inflammatory cytokine production.
• Difluprednate Ophthalmic · Thomas M. Lietman · Ophthalmology
  Difluprednate is a potent corticosteroid that suppresses inflammatory and immune responses in the eye by binding to glucocorticoid receptors.

Phase 3 pipeline (72)

• Hydronidone (270mg) · Beijing Continent Pharmaceutical Co, Ltd. · Immunology/Rheumatology
  Hydronidone is a corticosteroid that reduces inflammation and suppresses immune responses by binding to glucocorticoid receptors.
• Steroids therapy · Beijing Tiantan Hospital · Immunology
  Steroids therapy involves the use of corticosteroids to suppress the immune system and reduce inflammation.
• Standard: Dexamethasone · CCTU · Oncology, Rheumatology, Neurology
  Dexamethasone is a synthetic corticosteroid that functions as a potent anti-inflammatory agent by inhibiting the production of pro-inflammatory cytokines and mediators.
• EryDex High dose DSP · Quince Therapeutics S.p.A. · Immunology / Inflammatory disease
  EryDex High dose DSP is a dexamethasone formulation designed for enhanced delivery and bioavailability in treating inflammatory and immune-mediated conditions.
• EryDex Low dose DSP · Quince Therapeutics S.p.A. · Immunology
  EryDex Low dose DSP is a dexamethasone-based formulation designed to deliver corticosteroid therapy at reduced systemic doses while maintaining local therapeutic effect.
• prednisone, lactose · Medical University of Lodz · Immunology
  Prednisone is a corticosteroid that suppresses the immune system by inhibiting the production of inflammatory cytokines.
• Vehicle of Ophthalmic Loteprednol Etabonate · Bausch & Lomb Incorporated · Ophthalmology
  Loteprednol etabonate is a corticosteroid that reduces inflammation by inhibiting the production of prostaglandins.
• Corticosteroids for Systemic Use · University Hospital, Caen · Immunology, Rheumatology, Endocrinology
  Corticosteroids suppress immune and inflammatory responses by binding to glucocorticoid receptors and modulating gene expression in immune cells.
• vehicle of loteprednol etabonate · Bausch & Lomb Incorporated · Ophthalmology
  Loteprednol etabonate is a corticosteroid that works by inhibiting the inflammatory response.
• placebo to dexamethasone · Aswan University Hospital · Oncology
  Dexamethasone is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties.
• Vehicle of KPI-121 1.0% · Kala Pharmaceuticals, Inc. · Ophthalmology
  KPI-121 is a corticosteroid
• immediate treatment with corticosteroids · Fondation Ophtalmologique Adolphe de Rothschild · Ophthalmology / Immunology
  Corticosteroids suppress immune and inflammatory responses by binding to glucocorticoid receptors and inhibiting pro-inflammatory cytokine production.
• Shock-dependent hydrocortisone · UMC Utrecht · Critical Care
  Shock-dependent hydrocortisone is a corticosteroid that is administered in response to shock to reduce inflammation and support the body's response to stress.
• dexamethasone 0.1%/povidone-iodine 0.4% · University of Campinas, Brazil · Ophthalmology
  Dexamethasone is a corticosteroid that suppresses inflammation and immune responses, while povidone-iodine has antimicrobial properties.
• Topical corticosteroids (TCS) · AbbVie · Dermatology
  Topical corticosteroids suppress local immune and inflammatory responses by binding to glucocorticoid receptors in skin cells, reducing inflammation, itching, and redness.
• Placebo plus Dexamethasone HFA · Sumitomo Pharma America, Inc. · Respiratory/Immunology
  Dexamethasone is a corticosteroid that suppresses immune and inflammatory responses by binding to glucocorticoid receptors and inhibiting pro-inflammatory cytokine production.
• Prednisone (Cortancyl®) · Assistance Publique - Hôpitaux de Paris · Immunology
  Prednisone is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties.
• Prednisolones acetate · Bausch & Lomb Incorporated · Ophthalmology
  Prednisolone acetate is a corticosteroid that suppresses inflammation and immune responses by inhibiting the production of inflammatory cytokines and mediators.
• mometasone nasal inhalation · Sumitomo Pharma America, Inc. · Respiratory
  Mometasone is a corticosteroid that works by inhibiting the release of pro-inflammatory cytokines and mediators.
• Corticosteroids for Local Oral Treatment · October 6 University · Dermatology / Oral Medicine
  Corticosteroids reduce inflammation and suppress immune responses in oral tissues through glucocorticoid receptor activation.
• dual-release hydrocortisone · University of Palermo · Endocrinology
  Dual-release hydrocortisone delivers the corticosteroid in two phases to mimic the body's natural cortisol rhythm, providing anti-inflammatory and immunosuppressive effects.
• Plavina cream · Khon Kaen University · Dermatology
  Plavina cream is a topical corticosteroid used to reduce inflammation and itching.
• Local Corticosteroid Therapy · Spaulding Rehabilitation Hospital · Dermatology, Rheumatology, Immunology
  Local corticosteroid therapy reduces inflammation and immune response at the site of application by suppressing inflammatory mediators and immune cell activity.
• Intravitreal triamcinolone injections · Assistance Publique - Hôpitaux de Paris · Ophthalmology
  Triamcinolone is a corticosteroid that suppresses intraocular inflammation by inhibiting inflammatory mediators and immune cell activation in the vitreous.
• Intravitreal triamcinolone · University of Sao Paulo · Ophthalmology
  Intravitreal triamcinolone is a corticosteroid injected directly into the eye that suppresses inflammation and reduces vascular permeability in retinal diseases.
• NBP608 (Mid Potency) · SK Bioscience Co., Ltd. · Dermatology, Immunology, Inflammation
  NBP608 is a mid-potency corticosteroid that reduces inflammation by binding to glucocorticoid receptors and suppressing immune and inflammatory responses.
• therapeutic hydrocortisone · AIDS Malignancy Consortium · Immunology
  Therapeutic hydrocortisone is a corticosteroid that suppresses the immune system by inhibiting the production of inflammatory cytokines.
• prednisone discontinuation · Groupe Hospitalier Pitie-Salpetriere · Immunology
  Prednisone is a corticosteroid that suppresses the immune system by inhibiting the production of inflammatory cytokines.
• Fixed-duration dexamethasone · UMC Utrecht · Immunology
  Dexamethasone is a corticosteroid that suppresses immune and inflammatory responses by binding to glucocorticoid receptors and modulating gene expression.
• Rinderon® - DP = betamethasone dipropionate · LEO Pharma · Dermatology
  Rinderon inhibits the body's inflammatory response by suppressing the production of various pro-inflammatory cytokines.
• Intramuscular methylprednisolone acetate · Montefiore Medical Center · Immunology / Rheumatology / General anti-inflammatory
  Methylprednisolone acetate is a corticosteroid that suppresses the immune system and reduces inflammation by inhibiting inflammatory mediators and immune cell activation.
• Injection of methylprednisolone · Centre Hospitalier Universitaire Dijon · Immunology
  Methylprednisolone is a corticosteroid that suppresses the immune system and reduces inflammation by inhibiting pro-inflammatory cytokine production and immune cell activation.
• prednisone, colecalciferol, lactose · Medical University of Lodz · Immunology
  Prednisone is a corticosteroid that suppresses the immune system by inhibiting the production of inflammatory cytokines.
• Methyprednisolone sodium succinate · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Immunology
  Methylprednisolone sodium succinate is a corticosteroid that suppresses the immune system by inhibiting the production of inflammatory cytokines.
• Standard-of-care corticosteroid injections · Rhode Island Hospital · Immunology
  Corticosteroids reduce inflammation by inhibiting the production of pro-inflammatory cytokines and mediators.
• STN1012600 ophthalmic solution 0.002% · Santen Pharmaceutical Co., Ltd. · Ophthalmology
  STN1012600 ophthalmic solution 0.002% is a corticosteroid used to reduce inflammation in the eye.
• Steroid nasal spray · Sun Yat-sen University · Respiratory
  Steroid nasal sprays work by reducing inflammation in the nasal passages.
• STN1013800 ophthalmic solution · Santen Pharmaceutical Co., Ltd. · Ophthalmology
  STN1013800 ophthalmic solution is a corticosteroid used to treat inflammation in the eye.
• as-needed fluticasone propionate · Milton S. Hershey Medical Center · Respiratory
  Fluticasone propionate is a corticosteroid that works by reducing inflammation in the body.
• Methyl Prednisolone (MP) · Sana'a University · Immunology
  Methylprednisolone is a synthetic corticosteroid that suppresses the immune system by inhibiting the production of inflammatory cytokines.

Phase 2 pipeline (30)

• ALTIM, cortivazol injections · Assistance Publique - Hôpitaux de Paris · Rheumatology
  Cortivazol injections are corticosteroids that reduce inflammation and suppress the immune system.
• AN2898 ointment, 1% · Pfizer · Dermatology
  AN2898 ointment is a topical corticosteroid that reduces inflammation and itching by suppressing the immune system's response.
• Clobetasol 17-propionate · GEN İlaç ve Sağlık Ürünleri A.Ş. · Dermatology
  Glucocorticoid receptor agonist
• Corticosteroid: Prednisone · Bristol-Myers Squibb · Immunology
  Glucocorticoid receptor agonist
• Alclometasone cream · Pfizer · Dermatology
  Glucocorticoid receptor agonist
• EGP-437 with EyeGate® II System · Eyegate Pharmaceuticals, Inc. · Ophthalmology
  EGP-437 is a corticosteroid delivered directly to the eye via the EyeGate® II iontophoresis system to reduce ocular inflammation.
• Corticosteroid Eye Drop · Ocugen · Ophthalmology
  Corticosteroid eye drops reduce inflammation in the eye by suppressing the immune system.
• CHF 718 pMDI · Chiesi Farmaceutici S.p.A. · Respiratory
  CHF 718 pMDI is a corticosteroid used to reduce inflammation in the airways.
• CHF1535 pMDI · Chiesi Farmaceutici S.p.A. · Respiratory
  CHF1535 pMDI is a corticosteroid inhalation powder.
• Extra-fine hydrofluoroalkane beclometasone dipropionate · Research in Real-Life Ltd · Respiratory
  Beclometasone dipropionate is a corticosteroid that works by reducing inflammation in the body.
• Betamethasone dipropionate cream · LEO Pharma · Dermatology
  Betamethasone dipropionate cream is a topical corticosteroid that reduces inflammation and itching by suppressing the immune system.
• Active01 Cream · Dr. Reddys Laboratories, SA · Dermatology
  Active01 Cream is a topical corticosteroid used to reduce inflammation and itching in various skin conditions.
• Fluticasone propionate metred dose inhaler · Research in Real-Life Ltd · Respiratory
  Fluticasone propionate is a corticosteroid that works by reducing inflammation in the lungs.
• METHYLPREDNISOLONE SULEPTANATE · Immunology
  Methylprednisolone suleptanate works by binding to glucocorticoid receptors, which then suppress the expression of pro-inflammatory genes.
• A197 Ophthalmic Solution · Aramis Biosciences, Inc. · Ophthalmology
  A197 Ophthalmic Solution is a topical corticosteroid used to reduce inflammation in the eye.
• Betamethasone Sodium Phosphate 0.01% · Surface Ophthalmics, Inc. · Ophthalmology
  Betamethasone sodium phosphate is a corticosteroid that reduces inflammation and suppresses the immune system.
• Budesonide extrafine pMDI · Chiesi Farmaceutici S.p.A. · Respiratory
  Budesonide extrafine pMDI is a corticosteroid that works by reducing inflammation in the lungs.
• Corticosteroid: Methylprednisolone · Bristol-Myers Squibb · Oncology
  Glucocorticoid receptor agonist
• AGN-210669 ophthalmic solution, 0.05% · Allergan · Ophthalmology
  AGN-210669 ophthalmic solution is a corticosteroid used to reduce inflammation in the eye.
• Chlorofluorocarbon beclomethasone metered dose inhaler · Research in Real-Life Ltd · Respiratory
  Beclomethasone dipropionate is a corticosteroid that binds to glucocorticoid receptors, reducing inflammation and airway hyperresponsiveness.
• Beclomethasone dipropionate HFA Nasal Aerosol · Teva Branded Pharmaceutical Products R&D, Inc. · Respiratory
  Beclomethasone dipropionate is a corticosteroid that binds to glucocorticoid receptors, reducing inflammation and immune responses in the nasal passages.
• Betamethasone dipropionate aerosol spray · LEO Pharma · Dermatology
  Betamethasone dipropionate aerosol spray is a topical corticosteroid that reduces inflammation and suppresses the immune system.
• Betamethasone Dipropionate 0.05% Cream · Padagis LLC · Dermatology
  Betamethasone dipropionate is a corticosteroid that reduces inflammation and suppresses the immune system.
• Betnovat® ointment · LEO Pharma · Dermatology
  Betnovat ointment is a topical corticosteroid that reduces inflammation and itching by suppressing the immune system.
• CHF5993 pMDI · Chiesi Farmaceutici S.p.A. · Respiratory
  CHF5993 pMDI is a corticosteroid inhalation powder for the maintenance treatment of asthma and the treatment of chronic obstructive pulmonary disease (COPD).
• Budesonide 200 microgram · AstraZeneca · Respiratory
  Budesonide is a corticosteroid that works by inhibiting the release of pro-inflammatory mediators from mast cells and other cells.
• DE-089 ophthalmic solution · Santen Pharmaceutical Co., Ltd. · Ophthalmology
  DE-089 ophthalmic solution is a corticosteroid used to treat inflammation in the eye.
• Betamethasone - ACTIVE · Pediatrix · Immunology
  Betamethasone is a corticosteroid that suppresses the immune system and reduces inflammation by binding to glucocorticoid receptors and inhibiting pro-inflammatory cytokine production.
• Etaproctene · Immunology
  Etaproctene works by binding to glucocorticoid receptors in the body, which then suppresses the immune system and reduces inflammation.
• Corticosteroid with or without colchicine · Clínica Medellín - Grupo Quirónsalud · Oncology
  Glucocorticoid receptor agonist