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STN1012600 ophthalmic solution 0.002%
STN1012600 ophthalmic solution 0.002% is a corticosteroid used to reduce inflammation in the eye.
STN1012600 ophthalmic solution 0.002% is a corticosteroid used to reduce inflammation in the eye. Used for Treatment of non-infectious uveitis affecting the posterior segment of the eye.
At a glance
| Generic name | STN1012600 ophthalmic solution 0.002% |
|---|---|
| Sponsor | Santen Pharmaceutical Co., Ltd. |
| Drug class | Corticosteroid |
| Modality | Small molecule |
| Therapeutic area | Ophthalmology |
| Phase | Phase 3 |
Mechanism of action
Corticosteroids like STN1012600 work by inhibiting the production of inflammatory mediators, thereby reducing swelling and pain in the eye. This makes it an effective treatment for various ocular conditions. The exact mechanism of action involves the suppression of phospholipase A2, which is involved in the production of inflammatory eicosanoids.
Approved indications
- Treatment of non-infectious uveitis affecting the posterior segment of the eye
Common side effects
- Increased intraocular pressure
Key clinical trials
- A Long Term Study of STN1012600 in Subjects With Open Angle Glaucoma or Ocular Hypertension (PHASE3)
- A Comparative Confirmatory Study of STN1012600 in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension (PHASE3)
- Pharmacokinetic Study of STN1012600 Ophthalmic Solution in Healthy Adult Males Volunteers (PHASE1)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |