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Corticosteroid with or without colchicine
Glucocorticoid receptor agonist
Glucocorticoid receptor agonist Used for Rheumatoid arthritis, Psoriatic arthritis.
At a glance
| Generic name | Corticosteroid with or without colchicine |
|---|---|
| Sponsor | Clínica Medellín - Grupo Quirónsalud |
| Drug class | Corticosteroid |
| Target | Glucocorticoid receptor |
| Modality | Small molecule |
| Therapeutic area | Oncology |
| Phase | Phase 2 |
Mechanism of action
Corticosteroids exert their effects by binding to the glucocorticoid receptor, which then translocates to the nucleus and regulates gene expression.
Approved indications
- Rheumatoid arthritis
- Psoriatic arthritis
Common side effects
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Headache
- Fatigue
- Insomnia
- Dizziness
- Muscle weakness
- Weight gain
Key clinical trials
- Randomised Evaluation of COVID-19 Therapy (PHASE3)
- Therapeutic Approach in Colchicine-resistant Recurrent pEricarditis in Children (PHASE3)
- Clinical Outcome of Patients With COVID-19 Pneumonia Treated With Corticosteroids and Colchicine
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
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