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Steroid injections
Steroid injections deliver corticosteroids directly to inflamed tissues to suppress local immune responses and reduce inflammation.
Steroid injections deliver corticosteroids directly to inflamed tissues to suppress local immune responses and reduce inflammation. Used for Intra-articular injection for osteoarthritis and rheumatoid arthritis, Soft tissue injection for bursitis, tendinitis, and ligament sprains, Epidural injection for radiculopathy and spinal pain.
At a glance
| Generic name | Steroid injections |
|---|---|
| Also known as | Dexamethasone |
| Sponsor | Sutherland Medical Center |
| Drug class | Corticosteroid |
| Target | Glucocorticoid receptor |
| Modality | Small molecule |
| Therapeutic area | Rheumatology, Orthopedics, Pain Management |
| Phase | FDA-approved |
Mechanism of action
Corticosteroids work by binding to glucocorticoid receptors in cells, suppressing pro-inflammatory cytokine production and immune cell activation. When injected directly into affected areas (joints, soft tissues, bursae), they achieve high local concentrations while minimizing systemic exposure, providing rapid anti-inflammatory and immunosuppressive effects.
Approved indications
- Intra-articular injection for osteoarthritis and rheumatoid arthritis
- Soft tissue injection for bursitis, tendinitis, and ligament sprains
- Epidural injection for radiculopathy and spinal pain
Common side effects
- Local pain or discomfort at injection site
- Transient increase in pain (post-injection flare)
- Local infection or septic arthritis
- Systemic corticosteroid effects (with repeated injections)
- Skin atrophy or depigmentation at injection site
Key clinical trials
- Improving White Blood Cell Collection From Healthy Donors (PHASE4)
- Virotherapy and Natural History Study of KHSV-Associated Multricentric Castleman s Disease With Correlates of Disease Activity (PHASE2)
- An Open-label, Randomized, Single-dose, Two-treatment, Four-period, Fully Replicate Crossover Bioequivalence Study in Healthy Female Adult Participants Under Fasting Conditions Comparing the Test Product, Prontogest Solution for IM Injection With the Reference Product, Progesterone Injection (PHASE1)
- Efficacy of Micronized Natural Progesterone vs GnRH Antagonist in the Prevention of LH Peak During Ovarian Stimulation. (PHASE4)
- pAF for the Treatment of Osteoarthritis (PHASE1, PHASE2)
- Procedural Framing and Epidural Steroid Injection Outcomes (NA)
- Inflammatory Markers in Lumbar Radicular Pain Treated With PRF and TFESI
- Patient Satisfaction During Lomber Transforaminal Epidural Steroid Injection: The Role of Sedation, Anxiety, and Pain
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Steroid injections CI brief — competitive landscape report
- Steroid injections updates RSS · CI watch RSS
- Sutherland Medical Center portfolio CI