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prednisone, lactose
Prednisone is a corticosteroid that suppresses the immune system by inhibiting the production of inflammatory cytokines.
Prednisone is a corticosteroid that suppresses the immune system by inhibiting the production of inflammatory cytokines. Used for Rheumatoid arthritis, Multiple sclerosis, Asthma.
At a glance
| Generic name | prednisone, lactose |
|---|---|
| Also known as | Miflonide, Pulmicort |
| Sponsor | Medical University of Lodz |
| Drug class | Corticosteroid |
| Target | Glucocorticoid receptor |
| Modality | Small molecule |
| Therapeutic area | Immunology |
| Phase | Phase 3 |
Mechanism of action
Prednisone works by binding to the glucocorticoid receptor, which then translocates to the nucleus and regulates the expression of genes involved in inflammation. This leads to a decrease in the production of pro-inflammatory cytokines, such as IL-1, IL-6, and TNF-alpha, resulting in reduced inflammation and immune response.
Approved indications
- Rheumatoid arthritis
- Multiple sclerosis
- Asthma
Common side effects
- Weight gain
- Insomnia
- Hypertension
- Osteoporosis
- Glaucoma
- Cataracts
- Peptic ulcer disease
- Diabetes mellitus
- Mood changes
- Nervousness
Key clinical trials
- Trial of Colchicine Versus Prednisone for the Treatment of Acute CPPD Arthritis (PHASE3)
- Oral Corticosteroids for Post-infectious Cough in Adults (PHASE3)
- Dose Finding Study of Nemiralisib (GSK2269557) in Subjects With an Acute Moderate or Severe Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) (PHASE2)
- Effect of Steroids on Thrombosis (Blood Clot Formation) and Inflammation in Patients Undergoing Hip Surgery (NA)
- Pharmacological Modulations of Allergen-Specific Immunotherapy (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- prednisone, lactose CI brief — competitive landscape report
- prednisone, lactose updates RSS · CI watch RSS
- Medical University of Lodz portfolio CI