Last reviewed 2026-04-23 · How we verify

Plavina cream

Plavina cream is a topical corticosteroid used to reduce inflammation and itching.

Plavina cream is a topical corticosteroid used to reduce inflammation and itching. Used for Severe skin inflammation.

At a glance

Mechanism of action

Plavina cream works by inhibiting the production of inflammatory mediators in the skin, thereby reducing redness, swelling, and itching. This is achieved through the action of its active ingredient, which is a corticosteroid that binds to glucocorticoid receptors in the skin, leading to a decrease in the expression of pro-inflammatory genes.

Approved indications

• Severe skin inflammation

Common side effects

• Skin atrophy

Key clinical trials

• Efficacy Study on Symptomatic Control of Patient With Knee Osteoarthritis Between 14% of Plai (Plaivana®) to Placebo Gels (PHASE3)

Primary sources

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