{"id":"plavina-cream","safety":{"commonSideEffects":[{"rate":"unknown","effect":"Skin atrophy"}]},"_chembl":{"chemblId":"CHEMBL2108947","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Plavina cream works by inhibiting the production of inflammatory mediators in the skin, thereby reducing redness, swelling, and itching. This is achieved through the action of its active ingredient, which is a corticosteroid that binds to glucocorticoid receptors in the skin, leading to a decrease in the expression of pro-inflammatory genes.","oneSentence":"Plavina cream is a topical corticosteroid used to reduce inflammation and itching.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:29:10.337Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Severe skin inflammation"}]},"trialDetails":[{"nctId":"NCT01836393","phase":"PHASE3","title":"Efficacy Study on Symptomatic Control of Patient With Knee Osteoarthritis Between 14% of Plai (Plaivana®) to Placebo Gels","status":"COMPLETED","sponsor":"Khon Kaen University","startDate":"2013-01","conditions":"Knee Osteoarthritis","enrollment":120}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Plavina cream","genericName":"Plavina cream","companyName":"Khon Kaen University","companyId":"khon-kaen-university","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Plavina cream is a topical corticosteroid used to reduce inflammation and itching. Used for Severe skin inflammation.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}