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Betametasone (BETAMETHASONE)

FDA-approved approved Small molecule Quality 65/100

Betamethasone works by binding to the glucocorticoid receptor, which then triggers a series of downstream effects that reduce inflammation and suppress the immune system.

Betamethasone, also known as BETAMETHASONE, is a corticosteroid medication that targets the glucocorticoid receptor. Originally developed by a pharmaceutical company, it is now off-patent and available from generic manufacturers. Betamethasone is used to treat a range of conditions, including allergic reactions, ankylosing spondylitis, and adrenal insufficiency. It has a half-life of 5.6 hours and a bioavailability of 72%. Betamethasone was first approved by the FDA in 1961.

At a glance

Generic nameBETAMETHASONE
Drug classCorticosteroid
TargetGlucocorticoid receptor
ModalitySmall molecule
Therapeutic areaOncology
PhaseFDA-approved
First approval1961

Mechanism of action

Think of it like a key fitting into a lock. Betamethasone is the key that fits into the glucocorticoid receptor, which is like a lock on a cell. When the key fits in, it turns on a series of signals inside the cell that help to calm down the immune system and reduce inflammation.

Approved indications

Common side effects

Drug interactions

Key clinical trials

Primary sources

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SourceUsed for
FDA labelMechanism, indications, dosing, boxed warnings, drug interactions
ClinicalTrials.govTrial enrolment, design, endpoints, results