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Clobetasol 17-propionate
Glucocorticoid receptor agonist
Glucocorticoid receptor agonist Used for Severe skin conditions such as psoriasis, atopic dermatitis, and seborrheic dermatitis.
At a glance
| Generic name | Clobetasol 17-propionate |
|---|---|
| Sponsor | GEN İlaç ve Sağlık Ürünleri A.Ş. |
| Drug class | Corticosteroid |
| Target | Glucocorticoid receptor |
| Modality | Small molecule |
| Therapeutic area | Dermatology |
| Phase | Phase 2 |
Mechanism of action
Clobetasol 17-propionate is a potent topical corticosteroid that acts by binding to the glucocorticoid receptor, leading to anti-inflammatory and immunosuppressive effects.
Approved indications
- Severe skin conditions such as psoriasis, atopic dermatitis, and seborrheic dermatitis
Common side effects
- Skin atrophy
- Hypersensitivity reactions
Key clinical trials
- Treatment of Bullous Pemphigoid With Avdoralimab (IPH5401), an Anti-C5aR1 Monoclonal Antibody (PHASE2)
- Clinical Trial to Demonstrate That the Dual Laser Therapy is Effective for the Treatment of Vulvar Lichen Sclerosus (NA)
- Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib (PHASE2)
- Targeted Investigation of Microbiome 2 Treat Atopic Dermatitis (TIME-2) (PHASE1)
- Effectiveness of Micro-needling With 5 Fluorouracil Versus Potent Topical Steroids in the Treatment of Limited Vitiligo (EARLY_PHASE1)
- Evaluation of Fluid Retention Due to Superpotent Topical Corticosteroid (PHASE4)
- Photobiomodulation, Er:YAG Laser, and Clobetasol in the Treatment of Oral Lichen Planus. (NA)
- The TRIBECA Study (TRIessence/Byqlovi for Easier CAtaract Surgery) (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Clobetasol 17-propionate CI brief — competitive landscape report
- Clobetasol 17-propionate updates RSS · CI watch RSS
- GEN İlaç ve Sağlık Ürünleri A.Ş. portfolio CI