ABPO Forte Gel · Dermatology ABPO Forte Gel is a topical formulation containing azelaic acid that reduces bacterial colonization and normalizes keratinization to treat acne and rosacea.
adapalene/benzoyl peroxide · Dermatology Adapalene is a retinoid that normalizes skin cell differentiation and reduces inflammation, while benzoyl peroxide is an antimicrobial that kills acne-causing bacteria and reduces sebum production.
Adapalene/benzoyl peroxide gel, 0.1%/2.5% · Dermatology Adapalene is a retinoid that normalizes skin cell differentiation and reduces inflammation, while benzoyl peroxide kills acne-causing bacteria and provides additional antimicrobial activity.
Adapalene Gel, 0.1% · Dermatology Adapalene is a third-generation retinoid that binds to retinoic acid receptors (RARs) to normalize skin cell differentiation and reduce inflammation in acne.
Adapalene Gel, 0.1% + Tazarotene Cream, 0.1% · Dermatology This combination product delivers two retinoid receptor agonists that normalize skin cell differentiation and reduce inflammation to treat acne and photoaging.
adapalene gel, 0.3% · Dermatology Adapalene is a third-generation retinoid that binds to retinoic acid receptors (RARs) to normalize skin cell differentiation and reduce inflammation.
Advanced Eye Relief · Ophthalmology Advanced Eye Relief is an over-the-counter ophthalmic lubricant and decongestant that reduces eye redness and irritation by moisturizing the ocular surface and constricting blood vessels.
azelaic acid 15% gel · Dermatology Azelaic acid reduces bacterial colonization and normalizes keratinization while exerting anti-inflammatory and antimicrobial effects on the skin.
Azzalure or Dysport · Dermatology / Aesthetics Azzalure is a botulinum toxin type A that blocks acetylcholine release at the neuromuscular junction, paralyzing facial muscles and reducing wrinkles.
Bifonazole Cream · Dermatology / Infectious Disease Bifonazole is an imidazole antifungal that disrupts fungal cell membrane integrity by inhibiting ergosterol synthesis.
BPO · Dermatology BPO (benzoyl peroxide) kills acne-causing bacteria and reduces sebum production while promoting skin cell turnover.
Brimonidine 0.33% gel (Br) · Dermatology Brimonidine is an alpha-2 adrenergic agonist that constricts blood vessels and reduces redness in the skin.
Calcipotriene and betamethasone dipropionate ointment · Dermatology This combination ointment uses calcipotriene (a vitamin D analog) to normalize skin cell differentiation and betamethasone dipropionate (a potent corticosteroid) to reduce inflammation and immune activation in psoriatic plaques.
"Cetaphil Healing Ointment" · Dermatology Cetaphil Healing Ointment creates a protective barrier on the skin while providing emollient and humectant ingredients to promote wound healing and skin repair.
Ciclopirox NL · Dermatology/Infectious Disease Ciclopirox is a broad-spectrum antifungal agent that inhibits fungal enzyme systems by chelating polyvalent cations, disrupting cellular respiration and biosynthesis.
Clobetasol Propionate, 0.05% · Dermatology Clobetasol propionate is a potent corticosteroid that suppresses inflammatory and immune responses by binding to glucocorticoid receptors and inhibiting pro-inflammatory cytokine production.
Clobetasol Propionate 0.05% Foam · Dermatology Clobetasol propionate is a potent topical corticosteroid that suppresses inflammatory and immune responses in the skin by binding to glucocorticoid receptors.
Clobex Spray · Dermatology Clobex Spray is a potent topical corticosteroid that suppresses inflammatory and immune responses in the skin.
Facial Cleanser and Moisturizer SPF 30 · Dermatology This topical product provides physical and chemical sun protection while cleansing and moisturizing the facial skin.
Facial Moisturizer with SPF 50+ · Dermatology This product provides physical and chemical UV protection to prevent sun damage while delivering hydration to facial skin.
Ivermectin 1% cream (IVM) · Dermatology Ivermectin binds to glutamate-gated chloride channels in parasites and arthropods, causing paralysis and death of the organisms.
Lidocaine 7% + Tetracaine 7% cream · Dermatology / Pain Management Lidocaine and tetracaine are local anesthetics that block sodium channels in nerve cell membranes, preventing the initiation and conduction of nerve impulses to produce topical anesthesia.
Loceryl Nail Lacquer · Dermatology Amorolfine inhibits fungal sterol synthesis by blocking lanosterol demethylase, disrupting the integrity of the fungal cell membrane.
Loceryl NL · Dermatology Loceryl is an antifungal nail lacquer that inhibits fungal cell wall synthesis by disrupting ergosterol production.
Loceryl NL 12 weeks · Dermatology / Infectious Disease Loceryl is a topical antifungal that inhibits fungal sterol synthesis by blocking lanosterol 14α-demethylase, disrupting the fungal cell membrane.
Loceryl NL 15 months · Dermatology Amorolfine is a morpholine antifungal that inhibits fungal sterol synthesis by blocking both Δ14-reductase and Δ8-Δ7-isomerase enzymes in the ergosterol biosynthesis pathway.
Loceryl NL + Cosmetic varnish · Dermatology Amorolfine is a morpholine antifungal that inhibits fungal sterol synthesis by blocking both Δ14-reductase and Δ8-Δ7-isomerase enzymes in the ergosterol biosynthesis pathway.
Methyl Aminolaevulinate 16% Cream · Dermatology Methyl aminolaevulinate is a photosensitizing prodrug that accumulates in abnormal skin cells and generates reactive oxygen species when activated by red light, destroying target lesions.
Metronidazole gel 1% · Dermatology Metronidazole disrupts bacterial and protozoal DNA by generating reactive oxygen species and damaging nucleic acids, leading to cell death.
Oral doxycycline hyclate · Infectious Disease Doxycycline hyclate is a tetracycline antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit.
powder BoNT-A (BOTOX/Vistabel) · Dermatology; Neurology; Aesthetics Botulinum toxin type A blocks acetylcholine release at the neuromuscular junction by cleaving SNARE proteins, causing temporary muscle paralysis.
Product A Product A is a marketed pharmaceutical from Galderma R&D, but specific mechanistic details are not provided.
Product B · Dermatology Product B is a marketed dermatological agent from Galderma R&D, but specific mechanistic details are not publicly available.
Retin-A Micro Microsphere 0.1% · Dermatology Retin-A Micro delivers tretinoin (a vitamin A derivative) in microsphere form to normalize skin cell turnover and reduce comedone formation.
Phase 3 pipeline
Adapalene 0.1% / Benzoyl Peroxide 2.5% Gel · Dermatology Adapalene is a retinoid that normalizes skin cell differentiation and reduces inflammation, while benzoyl peroxide kills acne-causing bacteria and provides additional antimicrobial activity.
Adapalene 0.3% / BPO 2.5% gel · Dermatology Adapalene is a retinoid that normalizes skin cell differentiation and reduces inflammation, while benzoyl peroxide provides antimicrobial activity against acne-causing bacteria.
Adapalene BPO · Dermatology Adapalene is a retinoid that binds to retinoic acid receptors to normalize skin cell differentiation and reduce inflammation, while benzoyl peroxide provides antimicrobial activity against acne-causing bacteria.
adapalene lotion 0.1% · Dermatology Adapalene is a topical retinoid that works by binding to retinoic acid receptors, modulating gene expression and promoting cell turnover.
Adapalene Lotion Vehicle · Dermatology Adapalene is a third-generation retinoid that binds to retinoic acid receptors to normalize skin cell differentiation and reduce inflammation in acne.
Benzoyl Peroxide Gel 2.5% · Dermatology Benzoyl peroxide kills acne-causing bacteria and promotes skin cell turnover by generating reactive oxygen species.
botulinum toxin neuromodulator · Neurology, Aesthetics, Pain Management Botulinum toxin blocks acetylcholine release at the neuromuscular junction by cleaving SNARE proteins, causing temporary muscle paralysis.
c-PDT · Dermatology c-PDT is a photodynamic therapy approach that uses a photosensitizing agent activated by light to generate reactive oxygen species and destroy target cells.
C. propionate - Corticosteroid 1 · Dermatology Clobetasol propionate is a potent topical corticosteroid that suppresses inflammatory and immune responses in the skin by binding to glucocorticoid receptors.
C. propionate- Corticosteroid 2 · Dermatology Clobetasol propionate is a potent corticosteroid that suppresses inflammatory and immune responses by binding to glucocorticoid receptors and inhibiting pro-inflammatory cytokine production.
C. propionate -Corticosteroid 3 · Dermatology Clobetasol propionate is a potent topical corticosteroid that suppresses inflammatory and immune responses in the skin by binding to glucocorticoid receptors.
CD0271 · Dermatology CD0271 is a selective inhibitor of phosphodiesterase 4 (PDE4) that reduces inflammatory mediator production in immune cells.
CD0271 0.1% / CD1579 2.5% · Dermatology CD0271 and CD1579 are topical agents that work synergistically to reduce skin inflammation and improve dermatological conditions through complementary anti-inflammatory pathways.
CD0271 0.3% / CD1579 2.5% · Dermatology CD0271 and CD1579 are topical agents that work synergistically to reduce inflammation and improve skin barrier function in dermatological conditions.
CD07805/47 gel · Dermatology CD07805/47 gel is a topical retinoid that modulates skin cell differentiation and reduces inflammation for acne treatment.
CD07805/47 gel 0.5%/CD07805/47 Vehicle · Dermatology CD07805/47 is a topical retinoid that modulates retinoid receptor signaling to reduce inflammation and promote skin cell differentiation in dermatological conditions.
CD1579 · Dermatology CD1579 is a selective inhibitor of phosphodiesterase 4 (PDE4) that reduces inflammatory mediator production in immune cells.
CD5789 (trifarotene) · Dermatology Trifarotene is a selective retinoid X receptor (RXR) agonist that modulates gene expression to reduce inflammation and promote skin cell differentiation.
Clobex® Shampoo · Dermatology Clobetasol propionate is a potent topical corticosteroid that suppresses inflammatory and immune responses in the skin.
Clobex® Vehicle Shampoo · Dermatology Clobex Vehicle Shampoo delivers clobetasol propionate, a potent topical corticosteroid, to the scalp to reduce inflammation and suppress immune-mediated skin responses.
Corticosteroid 1- C. propionate · Dermatology Clobetasol propionate is a potent corticosteroid that suppresses inflammatory and immune responses by binding to glucocorticoid receptors and inhibiting pro-inflammatory cytokine production.
Corticosteroid 2 - C. propionate · Dermatology Clobetasol propionate is a potent corticosteroid that suppresses inflammatory and immune responses by binding to glucocorticoid receptors and inhibiting pro-inflammatory cytokine production.
Corticosteroid 3 - C. propionate · Dermatology Clobetasol propionate is a potent corticosteroid that suppresses inflammatory and immune responses by binding to glucocorticoid receptors and inhibiting pro-inflammatory cytokine production.
Drug: CD07805/47 gel · Dermatology CD07805/47 gel is a topical retinoid that promotes skin cell turnover and collagen remodeling to improve signs of photoaging and wrinkles.
Epiduo/Tactuo · Dermatology Epiduo/Tactuo combines adapalene (a retinoid) and benzoyl peroxide to reduce acne by normalizing skin cell turnover and killing acne-causing bacteria.
GK567 · Endocrinology / Diabetes GK567 is a glucokinase activator that enhances glucose metabolism in pancreatic beta cells to stimulate insulin secretion.
ketoconazole shampoo (2/week) · Dermatology Ketoconazole shampoo inhibits fungal growth by disrupting ergosterol synthesis in fungal cell membranes, reducing dandruff and seborrheic dermatitis.
MAL 16.8% cream · Dermatology MAL 16.8% cream is a topical formulation of methyl aminolevulinate that generates reactive oxygen species upon light activation to destroy abnormal skin cells.
MAL Vehicle Cream · Dermatology MAL Vehicle Cream is a topical formulation vehicle designed to deliver active pharmaceutical ingredients through the skin for localized therapeutic effect.
Metronidazole 0.75% cream · Dermatology Metronidazole disrupts bacterial and protozoal DNA, leading to cell death and reduction of microorganisms associated with rosacea and other inflammatory skin conditions.
Metvix and conventional PDT · Oncology / Dermatology Metvix is a photosensitizing agent that accumulates in abnormal skin cells and, when activated by light in photodynamic therapy (PDT), generates reactive oxygen species to destroy lesions.
Metvix and natural daylight PDT · Oncology/Dermatology Metvix (methyl aminolevulinate) is a photosensitizing agent that accumulates in abnormal skin cells and is activated by natural daylight to generate reactive oxygen species that destroy lesions.
Metvix cream · Dermatology/Oncology Metvix (methyl aminolevulinate) is a photosensitizing agent that accumulates in abnormal cells and generates reactive oxygen species when activated by light, destroying target lesions.
NDL-PDT · Dermatology NDL-PDT is a photodynamic therapy agent that generates reactive oxygen species upon light activation to destroy targeted tissue.
QM1114-DP · Dermatology QM1114-DP is a topical treatment that targets the inflammatory pathways in the skin.
tretinoin 0.05% emollient cream · Dermatology Tretinoin is a retinoid that promotes skin cell turnover and reduces acne by unclogging pores.
Phase 2 pipeline
AbobotulinumtoxinA dose 1 · Dermatology AbobotulinumtoxinA is a botulinum toxin type A that works by temporarily paralyzing muscles to reduce muscle spasms and improve muscle tone.
AbobotulinumtoxinA dose level 1 or 2 · Dermatology AbobotulinumtoxinA is a botulinum toxin type A that works by temporarily paralyzing muscle contractions.
CD07223 · Oncology CD07223 is a small molecule targeting the CD73 enzyme.
CD10367 1% Solution - Non-desquamated zone · Dermatology CD10367 is a topical solution designed to treat non-desquamated (non-scaling) skin lesions, likely through anti-inflammatory or keratolytic activity.
CD10367 3% Solution - Desquamated zone · Dermatology CD10367 3% Solution - Desquamated zone is a topical treatment that helps to remove the outer layer of the skin, reducing the appearance of desquamation.
CD1579 5% · Dermatology CD1579 5% is a topical retinoid that modulates cell growth and differentiation.
CD5024 0.3% cream · Dermatology CD5024 0.3% cream is a topical calcineurin inhibitor that suppresses the immune system by inhibiting T-cell activation.