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tretinoin 0.05% emollient cream
tretinoin 0.05% emollient cream is a Retinoid Small molecule drug developed by Galderma R&D. It is currently in Phase 3 development for Acne vulgaris, Fine wrinkles associated with photoaging. Also known as: tretinoin emollient cream 0.05%.
Tretinoin is a retinoid that promotes skin cell turnover and reduces acne by unclogging pores.
Tretinoin is a retinoid that promotes skin cell turnover and reduces acne by unclogging pores. Used for Acne vulgaris, Fine wrinkles associated with photoaging.
At a glance
| Generic name | tretinoin 0.05% emollient cream |
|---|---|
| Also known as | tretinoin emollient cream 0.05% |
| Sponsor | Galderma R&D |
| Drug class | Retinoid |
| Target | Nuclear retinoic acid receptors |
| Modality | Small molecule |
| Therapeutic area | Dermatology |
| Phase | Phase 3 |
Mechanism of action
Tretinoin works by binding to nuclear retinoic acid receptors, which modulate gene expression involved in keratinization and inflammation, leading to improved skin texture and reduced acne lesions.
Approved indications
- Acne vulgaris
- Fine wrinkles associated with photoaging
Common side effects
- Skin irritation
- Dryness
- Redness
Key clinical trials
- Effectiveness and Safety of Zingiber Officinale Transdermal Patch for Acne Vulgaris; Study of Interleukin 1 and Skin Microbiome (PHASE2, PHASE3)
- Treatment of Plane Warts With Topical and Oral Retinoids (PHASE4)
- Comparison of Effectiveness and Safety of Triple Combination Cream of Fucinolone Acetonide 0.01%, Hydroquinone 4%, Tretinoin 0.05% with Mometasone Furoate 0.1%, Hydroquinone 4%, Tretinoin 0.05% in the Treatment of Melasma (NA)
- Microneedle Versus Fractional CO₂ Laser for Skin Aging Treatment With Stem Cell Secretome in Indonesian Adult Women (NA)
- Treatment w/ Tri-Luma® Cream & Intense Pulsed Light (IPL) vs a Mild Inactive Control Cream & Intense Pulsed Light (IPL) in Melasma (PHASE4)
- Adapalene Gel 0.3% Versus Tretinoin 0.05% Emollient Cream for Treatment of Photodamage (PHASE3)
- Efficacy and Safety of Therapy With Tri-Luma® Cream in Sequence With Glycolic Acid Peels for Melasma (PHASE4)
- Effectivity of 1 Finger Tip Unit Compared to 2 Finger Tip Units 0.05% Tretinoin Cream (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- tretinoin 0.05% emollient cream CI brief — competitive landscape report
- tretinoin 0.05% emollient cream updates RSS · CI watch RSS
- Galderma R&D portfolio CI
Frequently asked questions about tretinoin 0.05% emollient cream
What is tretinoin 0.05% emollient cream?
How does tretinoin 0.05% emollient cream work?
What is tretinoin 0.05% emollient cream used for?
Who makes tretinoin 0.05% emollient cream?
Is tretinoin 0.05% emollient cream also known as anything else?
What drug class is tretinoin 0.05% emollient cream in?
What development phase is tretinoin 0.05% emollient cream in?
What are the side effects of tretinoin 0.05% emollient cream?
What does tretinoin 0.05% emollient cream target?
Related
- Drug class: All Retinoid drugs
- Target: All drugs targeting Nuclear retinoic acid receptors
- Manufacturer: Galderma R&D — full pipeline
- Therapeutic area: All drugs in Dermatology
- Indication: Drugs for Acne vulgaris
- Indication: Drugs for Fine wrinkles associated with photoaging
- Also known as: tretinoin emollient cream 0.05%