Last reviewed · How we verify
Advanced Eye Relief
Advanced Eye Relief is an over-the-counter ophthalmic lubricant and decongestant that reduces eye redness and irritation by moisturizing the ocular surface and constricting blood vessels.
Advanced Eye Relief is an over-the-counter ophthalmic lubricant and decongestant that reduces eye redness and irritation by moisturizing the ocular surface and constricting blood vessels. Used for Minor eye irritation and redness, Dry eye symptoms, Eye discomfort from environmental factors.
At a glance
| Generic name | Advanced Eye Relief |
|---|---|
| Sponsor | Galderma R&D |
| Drug class | Ophthalmic lubricant and decongestant |
| Modality | Small molecule |
| Therapeutic area | Ophthalmology |
| Phase | FDA-approved |
Mechanism of action
The product combines lubricating agents (typically polyethylene glycol or similar demulcents) to coat and hydrate the cornea and conjunctiva, along with a decongestant component (likely naphazoline or similar alpha-adrenergic agonist) that causes vasoconstriction of conjunctival blood vessels to reduce visible redness. This dual mechanism addresses both the dryness and hyperemia associated with minor eye irritation.
Approved indications
- Minor eye irritation and redness
- Dry eye symptoms
- Eye discomfort from environmental factors
Common side effects
- Temporary stinging or burning
- Rebound redness with prolonged use
- Mydriasis or blurred vision
Key clinical trials
- "Effectiveness of Mulligan Mobilization Technique and Proprioceptive Exercises Among Patients With Knee Osteoarthritis" (NA)
- Systemic Bioavailability Study Of Col-118 Administered Topically as a 0.18 % Facial Gel And Brimonidine Ophthalmic Solution 0.2% (PHASE2)
- Efficacy of Zylet vs. Lotemax for the Treatment of Ocular Surface Inflammation/MGD/Blepharitis (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Advanced Eye Relief CI brief — competitive landscape report
- Advanced Eye Relief updates RSS · CI watch RSS
- Galderma R&D portfolio CI