Botulinum toxin
This page covers all Botulinum toxin drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting SNAP-25 (synaptosome-associated protein of 25 kDa), SNARE complex (synaptosome-associated protein), SNARE complex (synaptobrevin, SNAP-25, syntaxin).
Targets
SNAP-25 (synaptosome-associated protein of 25 kDa) · SNARE complex (synaptosome-associated protein) · SNARE complex (synaptobrevin, SNAP-25, syntaxin) · SNAP-25 (synaptosomal-associated protein 25) · SNARE complex (synaptobrevin/VAMP) · acetylcholine release · SNARE complex (acetylcholine release machinery) · Acetylcholine release inhibitor · Acetylcholine release · SNAP-25
Marketed (15)
- OnabotulinumtoxinA (ONA) · Hexsel Dermatology Clinic · Dermatology, Neurology
OnabotulinumtoxinA blocks acetylcholine release at the neuromuscular junction, paralyzing muscles and reducing dynamic wrinkles and muscle contractions. - OnabotulinumtoxinA 145 UNT [Botox] · Beth Israel Deaconess Medical Center · Neurology, Dermatology, Aesthetics
OnabotulinumtoxinA blocks the release of acetylcholine at the neuromuscular junction by cleaving SNARE proteins, causing temporary muscle paralysis. - Botox® (onabotulinumtoxinA) · Seoul National University Hospital · Neurology, Dermatology, Aesthetics
OnabotulinumtoxinA blocks acetylcholine release at the neuromuscular junction by cleaving SNARE proteins, causing temporary muscle paralysis. - BOTOX®/VISTABEL® · AbbVie · Dermatology, Neurology, Aesthetics
BOTOX is a botulinum toxin that blocks acetylcholine release at the neuromuscular junction, causing temporary muscle paralysis. - OnabotulinumtoxinA 50 UNT [Botox Cosmetic] · Amir Moradi MD, MBA · Aesthetics / Dermatology
OnabotulinumtoxinA blocks acetylcholine release at the neuromuscular junction, paralyzing muscles and reducing dynamic wrinkles. - Onabotulinumtoxina for Injection · University of Pennsylvania · Neurology, Dermatology, Urology
Onabotulinumtoxina blocks the release of acetylcholine at the neuromuscular junction by cleaving SNARE proteins, causing temporary muscle paralysis. - Dysport® (abobotulinumtoxinA) · Seoul National University Hospital · Neurology, Dermatology, Aesthetics
Dysport blocks acetylcholine release at the neuromuscular junction by cleaving SNARE proteins, causing temporary muscle paralysis. - Incobotulinumtoxin A Injectable Product · University of Utah · Neurology, Dermatology, Aesthetics
Incobotulinumtoxin A blocks acetylcholine release at the neuromuscular junction by cleaving SNARE proteins, causing temporary muscle paralysis. - Onabotulinumtoxin A · Wake Forest University Health Sciences · Neurology, Dermatology, Urology
Onabotulinumtoxin A blocks acetylcholine release at the neuromuscular junction by cleaving SNARE proteins, causing temporary muscle paralysis. - OnabotulinumtoxinA 100 UNT · University of South Florida · Neurology; Dermatology; Aesthetics
OnabotulinumtoxinA blocks acetylcholine release at the neuromuscular junction by cleaving SNARE proteins, causing temporary muscle paralysis. - Chemodenervation (4 months) · University of Wisconsin, Madison · Neurology, Dermatology, Rehabilitation Medicine
Chemodenervation uses botulinum toxin to temporarily paralyze muscles by blocking acetylcholine release at the neuromuscular junction. - OnabotulinumtoxinA Injectable Product · University of Utah · Neurology, Dermatology, Ophthalmology
OnabotulinumtoxinA blocks acetylcholine release at the neuromuscular junction by cleaving SNARE proteins, causing temporary muscle paralysis. - Onabotulinum Toxin A · Walter Reed National Military Medical Center · Neurology, Dermatology, Ophthalmology
Onabotulinum toxin A blocks acetylcholine release at the neuromuscular junction by cleaving SNARE proteins, causing temporary muscle paralysis. - Abobotulinum toxin A · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau · Neurology, Dermatology, Aesthetics
Abobotulinum toxin A blocks acetylcholine release at the neuromuscular junction by cleaving SNARE proteins, causing temporary muscle paralysis. - AbobotulinumtoxinA (ABO) · Hexsel Dermatology Clinic · Dermatology, Neurology
AbobotulinumtoxinA blocks acetylcholine release at the neuromuscular junction by cleaving SNARE proteins, causing temporary muscle paralysis.
Phase 3 pipeline (18)
- Botox Inj · Huons Co., Ltd. · Neurology, Dermatology, Aesthetics
Botox (botulinum toxin type A) blocks acetylcholine release at the neuromuscular junction, causing temporary muscle paralysis. - Botox 200 UNT Injection · University of Gaziantep · Neurology, Dermatology, Aesthetics
Botulinum toxin type A blocks acetylcholine release at the neuromuscular junction, causing temporary muscle paralysis. - OnabotulinumtoxinA (BOTOX®) · Naval Medical Center Camp Lejeune · Neurology, Dermatology, Aesthetics
OnabotulinumtoxinA blocks the release of acetylcholine at the neuromuscular junction by cleaving SNARE proteins, causing temporary muscle paralysis. - onabotulinumtoxinA 44 U · Allergan · Neurology
onabotulinumtoxinA 44 U works by temporarily paralyzing muscles to treat various conditions. - IncobotulinumtoxinA (75 Units) · Merz Pharmaceuticals GmbH · Neurology, Dermatology, Aesthetics
IncobotulinumtoxinA blocks acetylcholine release at the neuromuscular junction by cleaving SNARE proteins, causing temporary muscle paralysis. - IncobotulinumtoxinA 100 UNT Injection [Xeomin] · University Of Perugia · Neurology, Dermatology, Aesthetics
IncobotulinumtoxinA blocks acetylcholine release at the neuromuscular junction by cleaving SNARE proteins, causing temporary muscle paralysis. - Botulinum toxin A (GSK1358820) · GlaxoSmithKline · Neurology; Aesthetics
Botulinum toxin A blocks acetylcholine release at the neuromuscular junction by cleaving SNARE proteins, causing temporary muscle paralysis. - Botox-Epic · National Cheng-Kung University Hospital · Aesthetics / Neurology
Botox-Epic is a botulinum toxin formulation that blocks acetylcholine release at the neuromuscular junction to reduce muscle contractions. - DWC202405, DWC202314 · Daewoong Pharmaceutical Co. LTD. · Neurology
DWC202405 and DWC202314 are both botulinum toxin type A serotypes. - Mentor Purified Toxin · Mentor Worldwide, LLC · Aesthetics / Neurology
Mentor Purified Toxin is a botulinum toxin preparation that blocks acetylcholine release at the neuromuscular junction by cleaving SNARE proteins. - OnabotulinumtoxinA (Vistabel®) · Merz Pharmaceuticals GmbH · Neurology
OnabotulinumtoxinA works by temporarily paralyzing muscles to treat various conditions. - BONT-A intra-prostatic injection · University Hospital, Bordeaux · Urology
Botulinum toxin type A injected directly into the prostate blocks acetylcholine release at nerve endings to reduce smooth muscle contractions and lower urinary symptoms. - Abobotulinumtoxin A · Neurology Center of New England P.C. · Neurology
Abobotulinumtoxin A blocks acetylcholine release at the neuromuscular junction by cleaving SNARE proteins, causing temporary muscle paralysis. - intra-articular botulinum toxin type a · Minneapolis Veterans Affairs Medical Center · Rheumatology
Intra-articular botulinum toxin type A works by inhibiting the release of acetylcholine, a neurotransmitter that causes muscle contraction. - DWC202404, DWC202314 · Daewoong Pharmaceutical Co. LTD. · Neurology
DWC202404 and DWC202314 are botulinum toxin type A serotypes used for the treatment of various conditions. - incobotulinumtoxinA (Xeomin) · Merz Pharmaceuticals GmbH · Neurology
IncobotulinumtoxinA is a botulinum toxin type A that works by blocking the release of acetylcholine, a neurotransmitter that causes muscle contractions. - Botox 100U · EuBiologics Co.,Ltd · Neurology, Dermatology, Aesthetics
Botox (botulinum toxin type A) blocks acetylcholine release at the neuromuscular junction, causing temporary muscle paralysis. - DaxibotulinumtoxinA for injection · Revance Therapeutics, Inc. · Aesthetics, Neurology
DaxibotulinumtoxinA is a botulinum toxin that blocks acetylcholine release at the neuromuscular junction, causing temporary muscle paralysis.
Phase 2 pipeline (4)
- AbobotulinumtoxinA dose level 1 or 2 · Galderma R&D · Dermatology
AbobotulinumtoxinA is a botulinum toxin type A that works by temporarily paralyzing muscle contractions. - AbobotulinumtoxinA dose 1 · Galderma R&D · Dermatology
AbobotulinumtoxinA is a botulinum toxin type A that works by temporarily paralyzing muscles to reduce muscle spasms and improve muscle tone. - Injection of Onabotulinum toxin · Swiss Paraplegic Research, Nottwil · Neurology
Blocks acetylcholine release at neuromuscular junctions - Formulation C: OnabotulinumtoxinA · Allergan · Neurology
OnabotulinumtoxinA works by blocking the release of acetylcholine, a neurotransmitter that causes muscle contraction.
Phase 1 pipeline (1)
- Adverse Reactions of Botox intramuscularly · ASIS Corporation · Neurology
Botulinum toxin inhibits acetylcholine release at neuromuscular junctions