SNAP-25 — Drug Target

All drugs that target SNAP-25 — marketed and clinical-stage. Includes 3 drug classes acting on this target.

Drug classes

Acetylcholine Release Inhibitor [EPC] · botulinum toxin · Botulinum toxin

Marketed (1)

• Botox · Allergan · Acetylcholine Release Inhibitor [EPC] · Neuroscience
  BOTOX blocks neuromuscular transmission by inhibiting acetylcholine release through cleavage of SNAP-25.

Phase 3 pipeline (1)

• incobotulinumtoxinA (Xeomin) · Merz Pharmaceuticals GmbH · botulinum toxin · Neurology
  IncobotulinumtoxinA is a botulinum toxin type A that works by blocking the release of acetylcholine, a neurotransmitter that causes muscle contractions.

Phase 2 pipeline (1)

• Injection of Onabotulinum toxin · Swiss Paraplegic Research, Nottwil · Botulinum toxin · Neurology
  Blocks acetylcholine release at neuromuscular junctions

Phase 1 pipeline (1)

• Adverse Reactions of Botox intramuscularly · ASIS Corporation · Botulinum toxin · Neurology
  Botulinum toxin inhibits acetylcholine release at neuromuscular junctions