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Injection of Onabotulinum toxin
Injection of Onabotulinum toxin is a Botulinum toxin Small molecule drug developed by Swiss Paraplegic Research, Nottwil. It is currently in Phase 2 development for Spasticity.
Blocks acetylcholine release at neuromuscular junctions
Blocks acetylcholine release at neuromuscular junctions Used for Spasticity.
At a glance
| Generic name | Injection of Onabotulinum toxin |
|---|---|
| Sponsor | Swiss Paraplegic Research, Nottwil |
| Drug class | Botulinum toxin |
| Target | SNAP-25 |
| Modality | Small molecule |
| Therapeutic area | Neurology |
| Phase | Phase 2 |
Mechanism of action
Onabotulinum toxin is a neurotoxin that cleaves SNAP-25, preventing acetylcholine release and leading to muscle paralysis.
Approved indications
- Spasticity
Common side effects
- Dysphagia
- Headache
- Injection site pain
Key clinical trials
- The Impact of Botox on Neuroimmune Interactions in Atopic Dermatitis (PHASE1)
- A Study to Compare the Safety and Efficacy of Dysport® and Botox® in Adults With Upper Limb Spasticity. (PHASE4)
- Assessing the Genitourinary Microbiome of Women With Overactive Bladder Undergoing Onabotulinum Toxin Type A Intradetrusor Injections
- Intraoral Administration of Botox in Patients With Dentoalveolar Neuropathic Pain (PHASE2)
- A Study Comparing the Safety, Efficacy, and Diffusion of Letibotulinum Toxin A Versus Other Botulinum Toxin Products in Adults With Moderate-to-Severe Forehead Wrinkles (PHASE4)
- Comparing Treatments for Refractory Overactive Bladder: Bladder Denervation vs Botulinum Toxin Injections (PHASE4)
- A Pilot Study Testing Onabotulinum Toxin A Versus Incobotulinum Toxin A Injections for Facial Wrinkles (EARLY_PHASE1)
- Effect of Intradetrusor onabotulinumtoxinA Injection Versus Conservative Management on Female Sexual Function in Patients With Bladder Pain Syndrome
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Injection of Onabotulinum toxin CI brief — competitive landscape report
- Injection of Onabotulinum toxin updates RSS · CI watch RSS
- Swiss Paraplegic Research, Nottwil portfolio CI
Frequently asked questions about Injection of Onabotulinum toxin
What is Injection of Onabotulinum toxin?
Injection of Onabotulinum toxin is a Botulinum toxin drug developed by Swiss Paraplegic Research, Nottwil, indicated for Spasticity.
How does Injection of Onabotulinum toxin work?
Blocks acetylcholine release at neuromuscular junctions
What is Injection of Onabotulinum toxin used for?
Injection of Onabotulinum toxin is indicated for Spasticity.
Who makes Injection of Onabotulinum toxin?
Injection of Onabotulinum toxin is developed by Swiss Paraplegic Research, Nottwil (see full Swiss Paraplegic Research, Nottwil pipeline at /company/swiss-paraplegic-research-nottwil).
What drug class is Injection of Onabotulinum toxin in?
Injection of Onabotulinum toxin belongs to the Botulinum toxin class. See all Botulinum toxin drugs at /class/botulinum-toxin.
What development phase is Injection of Onabotulinum toxin in?
Injection of Onabotulinum toxin is in Phase 2.
What are the side effects of Injection of Onabotulinum toxin?
Common side effects of Injection of Onabotulinum toxin include Dysphagia, Headache, Injection site pain.
What does Injection of Onabotulinum toxin target?
Injection of Onabotulinum toxin targets SNAP-25 and is a Botulinum toxin.
Related
- Drug class: All Botulinum toxin drugs
- Target: All drugs targeting SNAP-25
- Manufacturer: Swiss Paraplegic Research, Nottwil — full pipeline
- Therapeutic area: All drugs in Neurology
- Indication: Drugs for Spasticity
- Compare: Injection of Onabotulinum toxin vs similar drugs
- Pricing: Injection of Onabotulinum toxin cost, discount & access