Analgesic and antipyretic

This page covers all Analgesic and antipyretic drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Cyclooxygenase (COX) enzymes, Cyclooxygenase (COX) enzymes; possibly TRPV1 and other pain pathways, Cyclooxygenase (COX), primarily central nervous system isoforms.

Targets

Cyclooxygenase (COX) enzymes · Cyclooxygenase (COX) enzymes; possibly TRPV1 and other pain pathways · Cyclooxygenase (COX), primarily central nervous system isoforms · Cyclooxygenase (COX) · Cyclooxygenase (COX), primarily in central nervous system · Cyclooxygenase (COX-1, COX-2) · Cyclooxygenase (COX) enzymes (central nervous system) · Cyclooxygenase (COX) enzymes; central pain and temperature regulation pathways

Marketed (21)

• IV Acetaminophen (Treatment A) · Mallinckrodt · Pain Management
  Acetaminophen inhibits prostaglandin synthesis in the central nervous system to reduce pain and fever.
• IV Acetaminophen · Mallinckrodt · Pain Management
  Acetaminophen inhibits prostaglandin synthesis in the central nervous system to reduce pain and fever.
• Preop acetaminophen IV · AdventHealth · Pain Management
  Acetaminophen reduces pain and fever by inhibiting prostaglandin synthesis in the central nervous system.
• Acetaminophen IV/PO · The University of Texas Health Science Center, Houston · Pain Management
  Acetaminophen reduces pain and fever by inhibiting prostaglandin synthesis in the central nervous system.
• Tylenol (Acetaminophen) · University of Nebraska · Pain Management
  Acetaminophen reduces pain and fever by inhibiting prostaglandin synthesis in the central nervous system.
• Acetaminophen/APAP · John van den Anker · Pain Management
  Acetaminophen reduces pain and fever by inhibiting prostaglandin synthesis in the central nervous system.
• Acetaminophen Injection · Mount Sinai Hospital, Canada · Pain Management
  Acetaminophen inhibits prostaglandin synthesis in the central nervous system to reduce pain and fever.
• Panadol® · Sinew Pharma Inc. · Pain Management
  Panadol (paracetamol/acetaminophen) reduces pain and fever by inhibiting prostaglandin synthesis in the central nervous system.
• Effervescent paracetamol termalgin · Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina · Pain management
  Paracetamol inhibits prostaglandin synthesis by blocking cyclooxygenase enzymes, reducing pain and fever.
• acetaminophen IV · Nantes University Hospital · Pain Management
  Acetaminophen inhibits prostaglandin synthesis in the central nervous system to reduce pain and fever.
• Acetaminophen Injectable Product · Rush University Medical Center · Pain Management
  Acetaminophen inhibits prostaglandin synthesis in the central nervous system to reduce pain and fever.
• Acetaminophen tablets · Maoxiang Group Jilin Pharmaceutical Co., Ltd. · Pain Management
  Acetaminophen reduces pain and fever by inhibiting prostaglandin synthesis in the central nervous system.
• Postoperative pain management with acetaminophen · University Hospital Sestre Milosrdnice · Pain Management
  Acetaminophen reduces pain and fever by inhibiting prostaglandin synthesis in the central nervous system.
• Non- effervescent Paracetamol kern · Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina · Pain Management
  Paracetamol inhibits prostaglandin synthesis by blocking cyclooxygenase enzymes in the central nervous system, reducing pain and fever.
• Infusion with paracetamol · University of Helsinki · Pain management, Fever reduction
  Paracetamol inhibits prostaglandin synthesis in the central nervous system to reduce pain and fever.
• acetaminophen, IV preparation · The University of Texas Health Science Center at San Antonio · Pain Management, Fever
  Acetaminophen inhibits prostaglandin synthesis in the central nervous system to reduce pain and fever.
• Tylenol Pill · Shanghai Zhongshan Hospital · Pain Management
  Acetaminophen reduces pain and fever by inhibiting prostaglandin synthesis in the central nervous system.
• Acetaminophen (Ofirmev) · Brigham and Women's Hospital · Pain Management
  Acetaminophen reduces pain and fever by inhibiting prostaglandin synthesis in the central nervous system.
• Acetaminophen PO · The University of Texas Health Science Center, Houston · Pain Management
  Acetaminophen reduces pain and fever by inhibiting prostaglandin synthesis in the central nervous system.
• Acetaminophen (paracetamol) · Hellenic Society of Hematology · Pain Management
  Acetaminophen reduces pain and fever by inhibiting prostaglandin synthesis in the central nervous system.
• Per Os Acetaminophen · Hospital for Special Surgery, New York · Pain Management
  Acetaminophen reduces pain and fever by inhibiting prostaglandin synthesis in the central nervous system.

Phase 3 pipeline (9)

• Intranasal Paracetamol · Bezmialem Vakif University · Pain Management
  Intranasal paracetamol inhibits cyclooxygenase enzymes in the central nervous system to reduce pain and fever perception.
• Paracetamol 1% solution · Baxter Healthcare Corporation · Pain Management
  Paracetamol inhibits prostaglandin synthesis in the central nervous system to reduce pain and fever.
• Placebo to Acetaminophen/Paracetamol · Merck Sharp & Dohme LLC · Pain Management
  Acetaminophen reduces pain and fever by inhibiting prostaglandin synthesis in the central nervous system.
• Metamizole and Acetaminophen iv · Hospital General Universitario Elche · Pain Management, Fever Management
  Metamizole and acetaminophen are non-opioid analgesics and antipyretics that inhibit prostaglandin synthesis and modulate pain perception to reduce fever and pain.
• Acetaminophen, Analgesics, Non-Narcotic · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Pain Management
  Acetaminophen reduces pain and fever by inhibiting prostaglandin synthesis in the central nervous system.
• (1) Paracetamol injection · Ain Shams University · Pain Management
  Paracetamol inhibits prostaglandin synthesis by blocking cyclooxygenase enzymes in the central nervous system, reducing pain perception and fever.
• Paracetamol (500 mg) tablets · Novartis · Pain Management
  Paracetamol inhibits prostaglandin synthesis in the central nervous system to reduce pain and fever.
• Acetaminophen (or equivalent) · Merck Sharp & Dohme LLC · Pain Management
  Acetaminophen reduces pain and fever by inhibiting prostaglandin synthesis in the central nervous system.
• Commercial acetaminophen · Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division · Pain Management
  Acetaminophen reduces pain and fever by inhibiting prostaglandin synthesis in the central nervous system.