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acetaminophen IV

Nantes University Hospital · FDA-approved active Small molecule

Acetaminophen inhibits prostaglandin synthesis in the central nervous system to reduce pain and fever.

Acetaminophen inhibits prostaglandin synthesis in the central nervous system to reduce pain and fever. Used for Acute pain management, Fever reduction.

At a glance

Generic nameacetaminophen IV
SponsorNantes University Hospital
Drug classAnalgesic and antipyretic
TargetCyclooxygenase (COX) enzymes
ModalitySmall molecule
Therapeutic areaPain Management
PhaseFDA-approved

Mechanism of action

Acetaminophen works primarily through inhibition of cyclooxygenase (COX) enzymes in the brain and spinal cord, reducing prostaglandin production. This leads to decreased pain perception and hypothalamic temperature regulation. The intravenous formulation provides rapid systemic delivery for acute pain and fever management in clinical settings.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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