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Effervescent paracetamol termalgin
Paracetamol inhibits prostaglandin synthesis by blocking cyclooxygenase enzymes, reducing pain and fever.
Paracetamol inhibits prostaglandin synthesis by blocking cyclooxygenase enzymes, reducing pain and fever. Used for Mild to moderate pain, Fever reduction.
At a glance
| Generic name | Effervescent paracetamol termalgin |
|---|---|
| Sponsor | Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina |
| Drug class | Analgesic and antipyretic |
| Target | Cyclooxygenase (COX) |
| Modality | Small molecule |
| Therapeutic area | Pain management |
| Phase | FDA-approved |
Mechanism of action
Paracetamol (acetaminophen) works primarily through inhibition of central cyclooxygenase (COX) enzymes, which decreases prostaglandin production in the brain and spinal cord. This leads to reduced pain perception and lowering of the hypothalamic temperature set point. The effervescent formulation enhances rapid absorption and onset of action compared to standard tablets.
Approved indications
- Mild to moderate pain
- Fever reduction
Common side effects
- Hepatotoxicity (at high doses)
- Nausea
- Rash
Key clinical trials
- EVALUATION OF THE RELATIONSHIP BETWEEN EFFERVESCENT PARACETAMOL AND BLOOD PRESSURE. CLINICAL TRIAL. (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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