What are Inactivated viral vaccine drugs?

Inactivated viral vaccine drugs are pharmacologic agents that share a common mechanism (typically targeting Hepatitis A virus surface antigens). 46 are currently marketed, with 41 more in clinical development.

What are the marketed Inactivated viral vaccine drugs?

Marketed Inactivated viral vaccine drugs include Healive® Lot 3, IPV at 6 weeks of age, Havrix (HAV), Havrix Junior, Havrix 720 Junior, IPV-Al.

Inactivated viral vaccine

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

46 marketed 41 in Phase 3

This page covers all Inactivated viral vaccine drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Hepatitis A virus surface antigens, Poliovirus types 1, 2, and 3, Hepatitis A virus antigen.

Targets

Hepatitis A virus surface antigens · Poliovirus types 1, 2, and 3 · Hepatitis A virus antigen · Hepatitis A virus surface antigen · Poliovirus serotypes 1, 2, and 3 · Enterovirus 71 (EV71) viral antigens · poliovirus serotypes 1, 2, and 3 · Tick-borne encephalitis virus (TBEV) envelope proteins · Tick-borne encephalitis virus (TBEV) · Hepatitis A virus (HAV)

Marketed (46)

Healive® Lot 3 · Sinovac Biotech Co., Ltd · Immunology / Infectious Disease
Healive is an inactivated hepatitis A vaccine that stimulates the immune system to produce antibodies against hepatitis A virus.
IPV at 6 weeks of age · Centers for Disease Control and Prevention · Immunology / Infectious Disease
IPV (Inactivated Poliovirus Vaccine) stimulates the immune system to produce antibodies against poliovirus types 1, 2, and 3 by introducing inactivated viral particles.
Havrix (HAV) · Pfizer · Immunology / Infectious Disease
Havrix is an inactivated hepatitis A vaccine that stimulates the immune system to produce antibodies against hepatitis A virus.
Havrix Junior · GlaxoSmithKline · Immunology / Infectious Disease
Havrix Junior is an inactivated hepatitis A vaccine that stimulates the immune system to produce antibodies against hepatitis A virus.
Havrix 720 Junior · Chiang Mai University · Immunology / Infectious Disease
Havrix 720 Junior is an inactivated hepatitis A vaccine that stimulates the immune system to produce antibodies against hepatitis A virus.
IPV-Al · AJ Vaccines A/S · Immunology / Infectious Disease
IPV-Al is an inactivated poliovirus vaccine that stimulates the immune system to produce antibodies against all three poliovirus serotypes.
EV71 inactived vaccine（Vero cells） · Sinovac Biotech Co., Ltd · Immunology / Infectious Disease
This inactivated virus vaccine stimulates the immune system to produce antibodies and cellular immunity against enterovirus 71 (EV71) to prevent infection and disease.
fIPV (0.1mL) IM · Centers for Disease Control and Prevention · Immunology / Infectious Disease
fIPV is an inactivated polio vaccine that stimulates the immune system to produce antibodies against all three poliovirus serotypes, preventing poliomyelitis infection.
FSME-Immune vaccination · Medical University of Vienna · Immunology / Infectious Disease
FSME-Immune is an inactivated tick-borne encephalitis virus vaccine that stimulates the immune system to produce antibodies and cellular immunity against TBEV.
Purified Verocell Rabies Vaccine · Sanofi Pasteur, a Sanofi Company · Immunology / Infectious Disease
This vaccine stimulates the immune system to produce antibodies and cellular immunity against rabies virus by presenting inactivated viral antigens.
IMOVAX POLIO®: Inactive Poliovirus Vaccine · Sanofi Pasteur, a Sanofi Company · Immunology / Infectious Disease
IMOVAX POLIO stimulates the immune system to produce antibodies against all three types of poliovirus by introducing inactivated (killed) virus particles.
sIPV batch 3 · Institute of Medical Biology, Chinese Academy of Medical Sciences · Immunology / Infectious Disease
sIPV is an inactivated polio vaccine that stimulates the immune system to produce antibodies against poliovirus types 1, 2, and 3.
Seasonal trivalent inactivated influenza vaccine · PATH · Immunology
The vaccine stimulates the immune system to produce antibodies and cellular immunity against three strains of influenza virus, providing protection against seasonal flu infection.
FSME-IMMUN Vaccine · Region Örebro County · Immunology / Infectious Disease
FSME-IMMUN is an inactivated tick-borne encephalitis virus vaccine that stimulates the immune system to produce antibodies and cellular immunity against TBEV.
EV71 +SIV · Zhejiang Provincial Center for Disease Control and Prevention · Immunology / Infectious Disease
This is a bivalent vaccine combining inactivated enterovirus 71 (EV71) and simian immunodeficiency virus (SIV) components to elicit immune responses against both pathogens.
Havrix+Havrix · Sinovac Biotech Co., Ltd · Immunology / Infectious Disease
Havrix is an inactivated hepatitis A vaccine that stimulates the immune system to produce antibodies against hepatitis A virus.
TBE booster vaccination · Medical University of Vienna · Immunology / Infectious Disease
TBE booster vaccination stimulates the immune system to produce antibodies and cellular immunity against tick-borne encephalitis virus through repeated antigen exposure.
Sabin IPV + Sabin IPV + Sabin IPV · Zhejiang Provincial Center for Disease Control and Prevention · Immunology / Infectious Disease
Sabin IPV is an inactivated polio vaccine that stimulates the immune system to produce antibodies against all three poliovirus serotypes (1, 2, and 3).
Control Vaccine · Sinovac Biotech Co., Ltd · Immunology / Infectious Disease
Control Vaccine is an inactivated whole-virus vaccine that stimulates the immune system to produce antibodies and cellular immunity against SARS-CoV-2.
Inactivated SARS-CoV-2 Vaccine (Vero cell） · Sinovac Research and Development Co., Ltd. · Immunology / Infectious Disease
This inactivated vaccine stimulates the immune system to produce antibodies and cellular immunity against SARS-CoV-2 by presenting whole inactivated viral particles.
V - C - C+V · IlDong Pharmaceutical Co Ltd · Immunology / Infectious Disease
V-C-C+V is a combination vaccine containing inactivated varicella-zoster virus and other viral components designed to provide immunization against varicella (chickenpox) and related viral infections.
Havrix+Healive · Sinovac Biotech Co., Ltd · Immunology / Infectious Disease
Havrix+Healive is a combination vaccine that provides immunization against hepatitis A and hepatitis B through inactivated viral antigens.
Hepatitis A (control) · International Vaccine Institute · Immunology / Infectious Disease
This inactivated hepatitis A vaccine stimulates the immune system to produce antibodies against hepatitis A virus, providing protective immunity against infection.
fIPV (0.2mL) IM · Centers for Disease Control and Prevention · Immunology / Infectious Disease
fIPV is an inactivated polio vaccine that stimulates the immune system to produce antibodies against all three poliovirus serotypes, preventing polio infection.
SARS-CoV-2 Inactivated Vaccine · PT Bio Farma · Immunology / Infectious Disease
An inactivated whole-virus vaccine that stimulates the immune system to produce antibodies and cellular immunity against SARS-CoV-2 by presenting non-infectious viral particles.
HepA-I · Sinovac Biotech Co., Ltd · Immunology / Infectious Disease
HepA-I is an inactivated hepatitis A vaccine that stimulates the immune system to produce antibodies against hepatitis A virus.
Hepatitis A vaccine · MacroGenics · Immunology
Hepatitis A vaccine stimulates the immune system to produce antibodies against hepatitis A virus, providing protection against infection.
EV71 Vaccine only · Sinovac Biotech Co., Ltd · Immunology / Infectious Disease
The EV71 vaccine stimulates the immune system to produce antibodies and cellular immunity against Enterovirus 71, preventing infection and disease.
Inactivated COVID-19 Vaccine · Sinovac Research and Development Co., Ltd. · Immunology
This inactivated vaccine stimulates the immune system to produce antibodies and cellular immunity against SARS-CoV-2 by presenting inactivated viral particles.
High-dosage SARS-CoV-2 vaccine · Sinovac Biotech Co., Ltd · Immunology
This inactivated SARS-CoV-2 vaccine stimulates the immune system to produce antibodies and cellular immunity against the virus by presenting inactivated viral particles.
sIPV · China National Biotec Group Company Limited · Immunology / Infectious Disease
sIPV is an inactivated polio vaccine that stimulates the immune system to produce antibodies against poliovirus types 1, 2, and 3.
COVAX only (1st and 2nd dose) · China National Biotec Group Company Limited · Immunology / Infectious Disease
COVAX is an inactivated COVID-19 vaccine that stimulates the immune system to produce antibodies and cellular immunity against SARS-CoV-2 by presenting inactivated viral particles.
EV71 (inoculation vaccine) · Shandong Province Centers for Disease Control and Prevention · Immunology / Infectious Disease
EV71 vaccine stimulates the immune system to produce antibodies and cellular immunity against Enterovirus 71, preventing infection and disease.
HAVpur Junior · Crucell Holland BV · Immunology / Infectious Disease
HAVpur Junior is an inactivated hepatitis A vaccine that stimulates the immune system to produce antibodies against hepatitis A virus.
2wIPV+1sIPV · Sinovac Biotech Co., Ltd · Immunology / Infectious Disease
This is a combination inactivated polio vaccine regimen using two doses of whole-virus IPV followed by one dose of split-virus IPV to provide immunization against poliovirus types 1, 2, and 3.
EV71 vaccine · Sinovac Biotech Co., Ltd · Immunology / Infectious Disease
The EV71 vaccine stimulates the immune system to produce antibodies and cellular immunity against enterovirus 71, preventing infection and disease.
Healive+Havrix · Sinovac Biotech Co., Ltd · Immunology / Infectious Disease
Healive+Havrix is a combination vaccine that provides immunization against hepatitis A and hepatitis B through inactivated viral antigens.
Hepatitis A Virus · Novartis · Immunology / Infectious Disease
Hepatitis A Virus vaccine stimulates the immune system to produce antibodies against hepatitis A virus, providing protection against infection.
IXIARO®- Japanese Encephalitis vaccine · Medical University of Vienna · Immunology / Infectious Disease
IXIARO is an inactivated Japanese encephalitis virus vaccine that stimulates the immune system to produce antibodies and cellular immunity against Japanese encephalitis virus.
Sabin IPV · Centers for Disease Control and Prevention, China · Immunology / Infectious Disease
Sabin IPV is an inactivated polio vaccine that stimulates the immune system to produce antibodies against all three poliovirus serotypes, preventing poliomyelitis infection.

Phase 3 pipeline (41)

Twinrix™ Junior · GlaxoSmithKline · Immunology / Infectious Disease
Twinrix Junior is a combined vaccine that stimulates the immune system to produce antibodies against hepatitis A and hepatitis B viruses.
PoliorixTM · GlaxoSmithKline · Immunology / Infectious Disease
Poliorix is an inactivated poliomyelitis vaccine that stimulates the immune system to produce antibodies against all three poliovirus serotypes (1, 2, and 3).
Routine paediatric vaccine - Hepatitis A · Sanofi Pasteur, a Sanofi Company · Immunology / Infectious Disease
Hepatitis A vaccine stimulates the immune system to produce antibodies against hepatitis A virus, providing protection against infection.
Combined Hepatitis A and B vaccine · GlaxoSmithKline · Immunology / Infectious Disease
This vaccine stimulates the immune system to produce antibodies against hepatitis A and B viruses by presenting inactivated viral antigens.
Biological Vaccine VLA1553 · Valneva Austria GmbH · Immunology / Infectious Disease
VLA1553 is an inactivated chikungunya virus vaccine that stimulates the immune system to produce antibodies and cellular immunity against chikungunya virus infection.
Control IPV · Sinovac Biotech Co., Ltd · Immunology / Infectious Disease
Control IPV is an inactivated poliovirus vaccine that stimulates the immune system to produce antibodies against poliovirus types 1, 2, and 3.
CoronaVac Biofarma COVID-19 Vaccine · Dr. Soetomo General Hospital · Immunology / Infectious Disease
CoronaVac is an inactivated whole-virus COVID-19 vaccine that stimulates the immune system to produce antibodies and cellular immunity against SARS-CoV-2.
Purified inactivated rabies vaccine - Verorab® · Sanofi Pasteur, a Sanofi Company · Immunology / Infectious Disease
Verorab stimulates the immune system to produce antibodies and cellular immunity against rabies virus by presenting inactivated viral antigens.
IPV SSI · Statens Serum Institut · Immunology / Infectious Disease
IPV SSI is an inactivated poliovirus vaccine that stimulates the immune system to produce antibodies against all three poliovirus serotypes.
Purified Vero Rabies Vaccine · Sanofi Pasteur, a Sanofi Company · Immunology / Infectious Disease
Purified Vero Rabies Vaccine stimulates the immune system to produce antibodies and cellular immunity against rabies virus by presenting inactivated rabies antigen.
Twinrix™ Adult · GlaxoSmithKline · Immunology / Infectious Disease
Twinrix is a combined vaccine that stimulates the immune system to produce antibodies against both hepatitis A and hepatitis B viruses.
Hepatitis A Pediatric Vaccine · Sanofi Pasteur, a Sanofi Company · Immunology / Infectious Disease
This vaccine stimulates the immune system to produce antibodies against hepatitis A virus, providing protection against infection.
Inactivated Coronavac/Butantan vaccine · Federal University of Espirito Santo · Immunology
An inactivated whole-virus SARS-CoV-2 vaccine that stimulates adaptive immune responses to prevent COVID-19 infection.
three consecutive lots of EV71 vaccine · Sinovac Biotech Co., Ltd · Immunology / Infectious Disease
An inactivated enterovirus 71 (EV71) vaccine that stimulates the immune system to produce antibodies against EV71, preventing infection and disease.
Cell-culture rabies vaccine · GlaxoSmithKline · Infectious Disease / Immunology
A cell-culture derived rabies vaccine that stimulates the immune system to produce antibodies and cellular immunity against rabies virus.
Inactive Poliovirus Vaccine · Sanofi Pasteur, a Sanofi Company · Immunology / Infectious Disease
Inactive Poliovirus Vaccine stimulates the immune system to produce antibodies against all three serotypes of poliovirus without causing disease.
Havrix 720 · Crucell Holland BV · Immunology / Infectious Disease
Havrix 720 is an inactivated hepatitis A vaccine that stimulates the immune system to produce antibodies against hepatitis A virus.
HAV vaccine · International Agency for Research on Cancer · Immunology / Infectious Disease
HAV vaccine stimulates the immune system to produce antibodies against hepatitis A virus, providing protection against infection.
Havrix Inj · Boryung Pharmaceutical Co., Ltd · Immunology / Infectious Disease
Havrix is an inactivated hepatitis A vaccine that stimulates the immune system to produce antibodies against hepatitis A virus.
Havrix™-based investigational formulation · GlaxoSmithKline · Immunology / Infectious Disease
Havrix is an inactivated hepatitis A vaccine that stimulates the immune system to produce antibodies against hepatitis A virus.
Hepatitis A vaccine AVAXIM 80U · Sanofi Pasteur, a Sanofi Company · Immunology / Infectious Disease
AVAXIM 80U is an inactivated hepatitis A vaccine that stimulates the immune system to produce antibodies against hepatitis A virus.
Inactivated Split-virion influenza vaccine · Sanofi Pasteur, a Sanofi Company · Immunology / Infectious Disease
This vaccine stimulates the immune system to recognize and respond to inactivated influenza virus particles, providing protection against seasonal influenza infection.
BBIBP-CorV vaccine · Cogna Technology Solutions LLC · Immunology / Infectious Disease
BBIBP-CorV is an inactivated whole-virus COVID-19 vaccine that stimulates immune responses against SARS-CoV-2.
Intramuscular vaccine COVAXIN · Bharat Biotech International Limited · Immunology / Infectious Disease
COVAXIN is an inactivated whole-virus COVID-19 vaccine that stimulates immune responses against SARS-CoV-2 through presentation of viral antigens.
IC51 Japanese Encephalitis · Valneva Austria GmbH · Infectious Disease / Immunology
IC51 is an inactivated Japanese encephalitis virus vaccine that stimulates the immune system to produce antibodies and cellular immunity against Japanese encephalitis virus.
Havrix®720 · Valneva Austria GmbH · Immunology / Infectious Disease
Havrix 720 is an inactivated hepatitis A vaccine that stimulates the immune system to produce antibodies against hepatitis A virus.
CoronaVac/CoronaVac · Institut Pasteur de Tunis · Immunology / Infectious Disease
CoronaVac is an inactivated SARS-CoV-2 vaccine that stimulates the immune system to produce antibodies and cellular immunity against the virus.
C) primary immunizations with Ixiaro · Helsinki University Central Hospital · Immunology / Infectious Disease
Ixiaro is an inactivated Japanese encephalitis virus vaccine that stimulates the immune system to produce antibodies and cellular immunity against Japanese encephalitis virus.
Inactivated SARS-CoV-2 vaccine · Jiangsu Province Centers for Disease Control and Prevention · Immunology / Infectious Disease
This inactivated vaccine trains the immune system to recognize and neutralize SARS-CoV-2 by presenting killed viral particles that cannot cause infection.
IPV-Al SSI · Statens Serum Institut · Immunology / Infectious Disease
IPV-Al SSI is an inactivated poliovirus vaccine formulated with aluminum adjuvant to stimulate immune response against poliovirus types 1, 2, and 3.
EV71vac · Medigen Vaccine Biologics Corp. · Immunology / Infectious Disease
EV71vac is an inactivated vaccine that stimulates the immune system to produce antibodies and cellular immunity against Enterovirus 71 (EV71).
Inactivated Poliomyelitis vaccine · Sanofi Pasteur, a Sanofi Company · Immunology / Infectious Disease
Inactivated poliomyelitis vaccine stimulates the immune system to produce antibodies against all three serotypes of poliovirus, providing protection against polio infection.
Group C: Inactivated Polio Vaccine · Centers for Disease Control and Prevention · Immunology
Inactivated Polio Vaccine stimulates the immune system to produce antibodies against poliovirus by introducing chemically inactivated (killed) virus particles.
Japanese Encephalitis purified inactivated vaccine · Valneva Austria GmbH · Infectious Disease / Immunology
This inactivated vaccine stimulates the immune system to produce antibodies and cellular immunity against Japanese encephalitis virus.
COVID-19 Vaccine,Inactivated · Sinovac Research and Development Co., Ltd. · Immunology
An inactivated viral vaccine that stimulates the immune system to produce antibodies and cellular immunity against SARS-CoV-2 by presenting inactivated virus particles.
HDCV Comparator · Wilbur Chen, MD, MS · Immunology / Infectious Disease
HDCV (Human Diploid Cell Vaccine) is a rabies vaccine that stimulates the immune system to produce antibodies against rabies virus.
Marketed rabies vaccine · Sinovac Biotech Co., Ltd · Immunology / Infectious Disease
This vaccine stimulates the immune system to produce antibodies and cellular immunity against the rabies virus, preventing infection after exposure.
Sinopharm BIBP · Vaxxinity, Inc. · Immunology / Infectious Disease
Sinopharm BIBP is a COVID-19 inactivated vaccine that stimulates immune responses against SARS-CoV-2 by presenting inactivated viral particles to the immune system.
CoronaVac Vaccine · Clover Biopharmaceuticals AUS Pty · Immunology / Infectious Disease
CoronaVac is an inactivated SARS-CoV-2 vaccine that stimulates the immune system to produce antibodies and cellular immunity against the virus.
Hantavax injection · Green Cross Corporation · Immunology / Infectious Disease
Hantavax is an inactivated vaccine that stimulates the immune system to produce antibodies against hantavirus, preventing infection with hantaviruses that cause hemorrhagic fever with renal syndrome (HFRS).

Patent intelligence

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