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Purified inactivated rabies vaccine - Verorab®
Purified inactivated rabies vaccine - Verorab® is a Inactivated viral vaccine Biologic drug developed by Sanofi Pasteur, a Sanofi Company. It is currently in Phase 3 development for Rabies post-exposure prophylaxis, Rabies pre-exposure prophylaxis in high-risk individuals.
Verorab stimulates the immune system to produce antibodies and cellular immunity against rabies virus by presenting inactivated viral antigens.
Verorab stimulates the immune system to produce antibodies and cellular immunity against rabies virus by presenting inactivated viral antigens. Used for Rabies post-exposure prophylaxis, Rabies pre-exposure prophylaxis in high-risk individuals.
At a glance
| Generic name | Purified inactivated rabies vaccine - Verorab® |
|---|---|
| Sponsor | Sanofi Pasteur, a Sanofi Company |
| Drug class | Inactivated viral vaccine |
| Modality | Biologic |
| Therapeutic area | Immunology / Infectious Disease |
| Phase | Phase 3 |
Mechanism of action
Purified inactivated rabies vaccine contains rabies virus that has been chemically inactivated to eliminate infectivity while preserving immunogenic epitopes. When administered, it triggers both humoral (antibody) and cell-mediated immune responses, priming the immune system to recognize and neutralize live rabies virus upon exposure. This provides post-exposure prophylaxis when given shortly after potential rabies exposure, or pre-exposure prophylaxis in high-risk populations.
Approved indications
- Rabies post-exposure prophylaxis
- Rabies pre-exposure prophylaxis in high-risk individuals
Common side effects
- Injection site reactions (pain, erythema, swelling)
- Headache
- Myalgia
- Fever
- Nausea
Key clinical trials
- Study of Purified Vero Rabies Vaccine Compared With Two Reference Rabies Vaccines, Given in a Pre-exposure Regimen to Children and Adults and as Single Booster Dose to a Subset of Adults (PHASE3)
- Study of Purified Vero Rabies Vaccine Compared With a Reference Rabies Vaccine as Simulated Rabies Post-Exposure Prophylaxis in Adult and Pediatric Population in Thaïland (PHASE3)
- Study of Purified Vero Rabies Vaccine Compared With Two Reference Rabies Vaccines in a Simulated Post-Exposure Regimen in Adults (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Purified inactivated rabies vaccine - Verorab® CI brief — competitive landscape report
- Purified inactivated rabies vaccine - Verorab® updates RSS · CI watch RSS
- Sanofi Pasteur, a Sanofi Company portfolio CI
Frequently asked questions about Purified inactivated rabies vaccine - Verorab®
What is Purified inactivated rabies vaccine - Verorab®?
How does Purified inactivated rabies vaccine - Verorab® work?
What is Purified inactivated rabies vaccine - Verorab® used for?
Who makes Purified inactivated rabies vaccine - Verorab®?
What drug class is Purified inactivated rabies vaccine - Verorab® in?
What development phase is Purified inactivated rabies vaccine - Verorab® in?
What are the side effects of Purified inactivated rabies vaccine - Verorab®?
Related
- Drug class: All Inactivated viral vaccine drugs
- Manufacturer: Sanofi Pasteur, a Sanofi Company — full pipeline
- Therapeutic area: All drugs in Immunology / Infectious Disease
- Indication: Drugs for Rabies post-exposure prophylaxis
- Indication: Drugs for Rabies pre-exposure prophylaxis in high-risk individuals
- Compare: Purified inactivated rabies vaccine - Verorab® vs similar drugs
- Pricing: Purified inactivated rabies vaccine - Verorab® cost, discount & access