{"id":"purified-inactivated-rabies-vaccine-verorab","safety":{"commonSideEffects":[{"rate":"30-74","effect":"Injection site reactions (pain, erythema, swelling)"},{"rate":"5-20","effect":"Headache"},{"rate":"5-15","effect":"Myalgia"},{"rate":"1-10","effect":"Fever"},{"rate":"1-5","effect":"Nausea"}]},"_chembl":{"chemblId":"CHEMBL2107962","moleculeType":"Vaccine component"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Purified inactivated rabies vaccine contains rabies virus that has been chemically inactivated to eliminate infectivity while preserving immunogenic epitopes. When administered, it triggers both humoral (antibody) and cell-mediated immune responses, priming the immune system to recognize and neutralize live rabies virus upon exposure. This provides post-exposure prophylaxis when given shortly after potential rabies exposure, or pre-exposure prophylaxis in high-risk populations.","oneSentence":"Verorab stimulates the immune system to produce antibodies and cellular immunity against rabies virus by presenting inactivated viral antigens.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:30:43.310Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Rabies post-exposure prophylaxis"},{"name":"Rabies pre-exposure prophylaxis in high-risk individuals"}]},"trialDetails":[{"nctId":"NCT04127786","phase":"PHASE3","title":"Study of Purified Vero Rabies Vaccine Compared With Two Reference Rabies Vaccines, Given in a Pre-exposure Regimen to Children and Adults and as Single Booster Dose to a Subset of Adults","status":"COMPLETED","sponsor":"Sanofi Pasteur, a Sanofi Company","startDate":"2019-10-21","conditions":"Rabies, Healthy Volunteers","enrollment":1708},{"nctId":"NCT04478084","phase":"PHASE3","title":"Study of Purified Vero Rabies Vaccine Compared With a Reference Rabies Vaccine as Simulated Rabies Post-Exposure Prophylaxis in Adult and Pediatric Population in Thaïland","status":"COMPLETED","sponsor":"Sanofi Pasteur, a Sanofi Company","startDate":"2020-08-04","conditions":"Rabies (Healthy Volunteers)","enrollment":403},{"nctId":"NCT03965962","phase":"PHASE3","title":"Study of Purified Vero Rabies Vaccine Compared With Two Reference Rabies Vaccines in a Simulated Post-Exposure Regimen in Adults","status":"COMPLETED","sponsor":"Sanofi Pasteur, a Sanofi Company","startDate":"2019-07-01","conditions":"Rabies (Healthy Volunteers)","enrollment":640}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Purified inactivated rabies vaccine - Verorab®","genericName":"Purified inactivated rabies vaccine - Verorab®","companyName":"Sanofi Pasteur, a Sanofi Company","companyId":"sanofi","modality":"Biologic","firstApprovalDate":"","aiSummary":"Verorab stimulates the immune system to produce antibodies and cellular immunity against rabies virus by presenting inactivated viral antigens. Used for Rabies post-exposure prophylaxis, Rabies pre-exposure prophylaxis in high-risk individuals.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}