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Group C: Inactivated Polio Vaccine
Group C: Inactivated Polio Vaccine is a Inactivated viral vaccine Biologic drug developed by Centers for Disease Control and Prevention. It is currently in Phase 3 development for Poliomyelitis prevention, Routine childhood immunization against poliovirus types 1, 2, and 3.
Inactivated Polio Vaccine stimulates the immune system to produce antibodies against poliovirus by introducing chemically inactivated (killed) virus particles.
Inactivated Polio Vaccine stimulates the immune system to produce antibodies against poliovirus by introducing chemically inactivated (killed) virus particles. Used for Poliomyelitis prevention, Routine childhood immunization against poliovirus types 1, 2, and 3.
At a glance
| Generic name | Group C: Inactivated Polio Vaccine |
|---|---|
| Sponsor | Centers for Disease Control and Prevention |
| Drug class | Inactivated viral vaccine |
| Modality | Biologic |
| Therapeutic area | Immunology |
| Phase | Phase 3 |
Mechanism of action
The vaccine contains three serotypes of poliovirus that have been inactivated through chemical treatment, rendering them non-infectious. When administered, these inactivated viral particles trigger both humoral (antibody) and cellular immune responses, leading to the production of neutralizing antibodies against all three poliovirus types. This provides protection against wild-type poliovirus infection and disease.
Approved indications
- Poliomyelitis prevention
- Routine childhood immunization against poliovirus types 1, 2, and 3
Common side effects
- Injection site soreness or swelling
- Fever
- Irritability or fussiness
- Mild rash
Key clinical trials
- A Study on the Immune Response and Safety of a Multicomponent Shigella Vaccine in Preventing Shigellosis in Infants (PHASE2)
- Study of a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Given With Routine Pediatric Vaccines in Healthy Infants and Toddlers in India and the Republic of South Africa (PHASE3)
- A Study on the Safety and Immune Responses to the GVGH altSonflex1-2-3 Vaccine Against Shigellosis in Adults, Children, and Infants (PHASE1)
- Study on a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Compared to a Meningococcal Reference Vaccine, and When Given Alone or With Two Other Vaccines in Healthy Adolescents (PHASE3)
- A Study to Evaluate the Safety and Immunogenicity of VLP-Polio in Infants and Toddlers (PHASE1, PHASE2)
- A Phase II/III Study to Evaluate the Immunogenicity, Safety and Lot-to-lot Consistency of LBVD, a Fully Liquid Hexavalent Diphtheria-tetanus-whole Cell Pertussis-hepatitis B-poliovirus-Haemophilus Influenzae Type b Conjugate (DTwP-HepB-IPV-Hib) Vaccine, in Healthy Infants as Primary Series (PHASE2, PHASE3)
- A Clinical Trial of Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed(DTcP) (PHASE3)
- Immunogenicity and Safety Study of a Quadrivalent Meningococcal Conjugate Vaccine When Co-administered With Routine Pediatric Vaccines in Healthy Infants and Toddlers in Europe (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Group C: Inactivated Polio Vaccine CI brief — competitive landscape report
- Group C: Inactivated Polio Vaccine updates RSS · CI watch RSS
- Centers for Disease Control and Prevention portfolio CI
Frequently asked questions about Group C: Inactivated Polio Vaccine
What is Group C: Inactivated Polio Vaccine?
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What is Group C: Inactivated Polio Vaccine used for?
Who makes Group C: Inactivated Polio Vaccine?
What drug class is Group C: Inactivated Polio Vaccine in?
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Related
- Drug class: All Inactivated viral vaccine drugs
- Manufacturer: Centers for Disease Control and Prevention — full pipeline
- Therapeutic area: All drugs in Immunology
- Indication: Drugs for Poliomyelitis prevention
- Indication: Drugs for Routine childhood immunization against poliovirus types 1, 2, and 3
- Compare: Group C: Inactivated Polio Vaccine vs similar drugs
- Pricing: Group C: Inactivated Polio Vaccine cost, discount & access