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Inactivated Split-virion influenza vaccine
Inactivated Split-virion influenza vaccine is a Inactivated viral vaccine Biologic drug developed by Sanofi Pasteur, a Sanofi Company. It is currently in Phase 3 development for Seasonal influenza prevention in adults and children. Also known as: Vaxigrip.
This vaccine stimulates the immune system to recognize and respond to inactivated influenza virus particles, providing protection against seasonal influenza infection.
This vaccine stimulates the immune system to recognize and respond to inactivated influenza virus particles, providing protection against seasonal influenza infection. Used for Seasonal influenza prevention in adults and children.
At a glance
| Generic name | Inactivated Split-virion influenza vaccine |
|---|---|
| Also known as | Vaxigrip |
| Sponsor | Sanofi Pasteur, a Sanofi Company |
| Drug class | Inactivated viral vaccine |
| Modality | Biologic |
| Therapeutic area | Immunology / Infectious Disease |
| Phase | Phase 3 |
Mechanism of action
The split-virion formulation contains disrupted influenza virus particles that present viral antigens to the immune system without causing infection. This triggers both humoral (antibody) and cellular immune responses, enabling the body to mount a rapid defense against subsequent exposure to circulating influenza strains. The inactivated nature ensures safety while maintaining immunogenicity.
Approved indications
- Seasonal influenza prevention in adults and children
Common side effects
- Injection site soreness or erythema
- Myalgia
- Headache
- Fatigue
- Low-grade fever
Key clinical trials
- Influenza Vaccine (Split Virion), Inactivated, Quadrivalent in Pregnant Women (PHASE3)
- Study to Evaluate Immunogenicity and Safety of a High-Dose Influenza Vaccine in Adults 50 Through 64 Years of Age (PHASE3)
- Clinical Trials of Quadrivalent Influenza Vaccine (PHASE1, PHASE2)
- Immunogenicity and Safety of Butantan Quadrivalent Influenza Vaccine (Split Virion, Inactivated) in Infants and Children . (PHASE3)
- Study to Evaluate the Effectiveness of a High-Dose Quadrivalent Influenza Vaccine (QIV-HD) Compared to a Standard-Dose Quadrivalent Influenza Vaccine (QIV-SD) in Adults 65 Years of Age and Older (PHASE3)
- Exploration on the Quadrivalent Influenza Vaccine Immunization Schedule for Children Aged 3-8 Years
- Study to Assess the Immune Response and the Safety Profile of a High-Dose Quadrivalent Influenza Vaccine (QIV-HD) Compared to a Standard-Dose Quadrivalent Influenza Vaccine (QIV-SD) in Europeans Adults 60 Years of Age and Older (PHASE3)
- Simultaneous Administration Study of Varicella Attenuated Live Vaccine and Trivalent Inactivated Influenza Vaccine (Split Virion) (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Inactivated Split-virion influenza vaccine CI brief — competitive landscape report
- Inactivated Split-virion influenza vaccine updates RSS · CI watch RSS
- Sanofi Pasteur, a Sanofi Company portfolio CI
Frequently asked questions about Inactivated Split-virion influenza vaccine
What is Inactivated Split-virion influenza vaccine?
How does Inactivated Split-virion influenza vaccine work?
What is Inactivated Split-virion influenza vaccine used for?
Who makes Inactivated Split-virion influenza vaccine?
Is Inactivated Split-virion influenza vaccine also known as anything else?
What drug class is Inactivated Split-virion influenza vaccine in?
What development phase is Inactivated Split-virion influenza vaccine in?
What are the side effects of Inactivated Split-virion influenza vaccine?
Related
- Drug class: All Inactivated viral vaccine drugs
- Manufacturer: Sanofi Pasteur, a Sanofi Company — full pipeline
- Therapeutic area: All drugs in Immunology / Infectious Disease
- Indication: Drugs for Seasonal influenza prevention in adults and children
- Also known as: Vaxigrip
- Compare: Inactivated Split-virion influenza vaccine vs similar drugs
- Pricing: Inactivated Split-virion influenza vaccine cost, discount & access