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Sabin IPV + Sabin IPV + Sabin IPV
Sabin IPV is an inactivated polio vaccine that stimulates the immune system to produce antibodies against all three poliovirus serotypes (1, 2, and 3).
Sabin IPV is an inactivated polio vaccine that stimulates the immune system to produce antibodies against all three poliovirus serotypes (1, 2, and 3). Used for Prevention of poliomyelitis caused by poliovirus types 1, 2, and 3.
At a glance
| Generic name | Sabin IPV + Sabin IPV + Sabin IPV |
|---|---|
| Sponsor | Zhejiang Provincial Center for Disease Control and Prevention |
| Drug class | inactivated viral vaccine |
| Target | poliovirus serotypes 1, 2, and 3 |
| Modality | Biologic |
| Therapeutic area | Immunology / Infectious Disease |
| Phase | FDA-approved |
Mechanism of action
Sabin IPV contains inactivated (killed) poliovirus particles that trigger humoral and cellular immune responses without causing disease. The vaccine elicits production of neutralizing antibodies against poliovirus types 1, 2, and 3, providing protection against poliomyelitis. The triple formulation ensures comprehensive coverage against all circulating wild-type and vaccine-derived poliovirus strains.
Approved indications
- Prevention of poliomyelitis caused by poliovirus types 1, 2, and 3
Common side effects
- Injection site pain, redness, or swelling
- Fever
- Myalgia
Key clinical trials
- Phase IV Clinical Study of Sequential Vaccination of Sabin Strain and Wild Strain Inactivated Poliovirus Vaccine (PHASE4)
- Phase IV Clinical Study of sIPV Administration in Adolescent and Adult Populations (PHASE4)
- the Five-year Antibody Persistence After Immunization With IPV, MMR and HepA-L Vaccines
- Study of a Novel Type 1 Oral Poliomyelitis Vaccine in Bangladesh (PHASE2)
- Phase III Clinical Trial of Sabin Strain Inactivated Poliovirus Vaccine (Vero Cell) (PHASE3)
- A Multi-center, Open-labelled, Randomized, Controlled, Extended Phase Ⅲ Clinical Trial of sIPV Vaccine (PHASE3)
- A Study on the Immune Response and Safety of Inactivated Poliovirus Vaccine (IPV) When Co-administered With Human Rotavirus (HRV) Porcine Circovirus (PCV)-Free Vaccine in Healthy Chinese Infants (PHASE3)
- Study of Concomitant Administration of the sIPV and DTaP or MMR (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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