Anticoagulant
This page covers all Anticoagulant drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Antithrombin III (enhancer); Factor Xa and Factor IIa (indirect targets), Vitamin K-dependent coagulation factors (II, VII, IX, X) or thrombin/Factor Xa, Antithrombin III, Coagulation Factors Xa and IIa.
Targets
Antithrombin III (enhancer); Factor Xa and Factor IIa (indirect targets) · Vitamin K-dependent coagulation factors (II, VII, IX, X) or thrombin/Factor Xa · Antithrombin III, Coagulation Factors Xa and IIa · Antithrombin III; Coagulation Factors Xa and IIa · Antithrombin III (indirect target); Thrombin (Factor IIa) and Factor Xa (downstream targets) · Antithrombin III (indirect target); Thrombin and Factor Xa (downstream targets) · Antithrombin III (indirect); Thrombin and Factor Xa (downstream targets) · Antithrombin III (enhancer); Thrombin (Factor IIa) and Factor Xa (indirect inhibition) · Ionized calcium (Ca2+) · Antithrombin III (indirect); Factor Xa and Factor IIa
Marketed (27)
- full amount low molecular weight heparin · Beijing Anzhen Hospital · Cardiovascular
Low molecular weight heparin inhibits blood coagulation by enhancing the activity of antithrombin III, which inactivates clotting factors Xa and IIa. - Traditional anticoagulation · University of Sao Paulo General Hospital · Cardiovascular
Traditional anticoagulation prevents blood clot formation by inhibiting coagulation cascade factors, typically through vitamin K antagonism or direct thrombin/factor Xa inhibition. - Heparin Sodium In Plastic Container · Fresenius Kabi · Cardiovascular
Heparin enhances Antithrombin III activity to inhibit coagulation factors Xa and IIa. - Heparin Sodium In Plastic Container · Fresenius Kabi
Heparin enhances Antithrombin III activity to inhibit coagulation factors Xa and IIa. - Low-dose heparin · San Filippo Neri General Hospital · Cardiovascular
Low-dose heparin inhibits blood coagulation by potentiating antithrombin III, which inactivates clotting factors IIa and Xa. - Heparin sodium lock solution · Hospital Civil de Guadalajara · Cardiovascular / Thromboembolism Prevention
Heparin sodium inhibits blood coagulation by potentiating antithrombin III, which inactivates thrombin and other clotting factors. - Heparin administration · Anemia Working Group Romania · Cardiovascular
Heparin is an anticoagulant that inhibits blood clotting by enhancing the activity of antithrombin III, which inactivates thrombin and other clotting factors. - Standard Dose of Unfractionated Heparin · University of California, Los Angeles · Cardiovascular
Unfractionated heparin inhibits blood coagulation by enhancing the activity of antithrombin III, which inactivates thrombin and other clotting factors. - Trissodium Citrate 30% · University of Sao Paulo · Hematology
Trisodium citrate acts as an anticoagulant by chelating calcium ions, thereby inhibiting the coagulation cascade and preventing blood clot formation. - low molecule heparin · Second Affiliated Hospital, School of Medicine, Zhejiang University · Cardiovascular
Low molecular weight heparin inhibits blood coagulation by enhancing the activity of antithrombin III, which inactivates clotting factors Xa and IIa. - prophylactic heparin · Matthew Neal MD · Cardiovascular
Prophylactic heparin inhibits blood clotting by enhancing the activity of antithrombin III, preventing thrombus formation. - Standard heparin dose · University of Utah · Cardiovascular
Standard heparin inhibits blood coagulation by enhancing the activity of antithrombin III, which inactivates thrombin and other clotting factors. - Continuation of oral anticoagulants · St. Antonius Hospital · Cardiovascular
Oral anticoagulants prevent blood clot formation by inhibiting coagulation cascade factors, reducing thromboembolism risk. - Anticoagulation with heparin · Boston Scientific Corporation · Cardiovascular
Heparin inhibits blood coagulation by enhancing the activity of antithrombin III, which inactivates thrombin and other clotting factors. - High dose of Unfractionated Heparin · University of Patras · Cardiovascular
High-dose unfractionated heparin inhibits blood coagulation by potentiating antithrombin III, which inactivates thrombin and other clotting factors. - Heparin Sodium In Plastic Container · Fresenius Kabi
Heparin enhances Antithrombin III activity to inhibit coagulation factors Xa and IIa. - Standard dose heparin · San Filippo Neri General Hospital · Cardiovascular
Heparin inhibits blood coagulation by enhancing the activity of antithrombin III, which inactivates thrombin and other clotting factors. - Heparin fixed doses · SANE-Society of Anesthesiology · Cardiovascular
Heparin is an anticoagulant that inhibits blood clotting by potentiating antithrombin III, which inactivates thrombin and other clotting factors. - Heparin Sodium In Plastic Container · Fresenius Kabi
Heparin enhances Antithrombin III activity to inhibit coagulation factors Xa and IIa. - Heparin anticoagulation · University Medical Centre Ljubljana · Cardiovascular
Heparin inhibits blood coagulation by enhancing the activity of antithrombin III, which inactivates thrombin and other clotting factors. - Unfractionated heparin(UFH) · Beijing Chao Yang Hospital · Cardiovascular
Unfractionated heparin inhibits blood coagulation by enhancing the activity of antithrombin III, which inactivates thrombin and other clotting factors. - Un-fractionated heparin · Deutsches Herzzentrum Muenchen · Cardiovascular
Unfractionated heparin inhibits blood coagulation by enhancing the activity of antithrombin III, which inactivates thrombin and other clotting factors. - Heparin or Bivalirudin · CCRF Consulting Co., Ltd. · Cardiovascular
Heparin and bivalirudin are anticoagulants that prevent blood clot formation by inhibiting thrombin and other coagulation factors. - Anticoagulant Therapy · Shenyang Northern Hospital · Cardiovascular
Anticoagulant therapy prevents blood clot formation by inhibiting coagulation cascade factors or platelet aggregation. - Unfractionated Heparin IV · The TIMI Study Group · Cardiovascular
Unfractionated heparin inhibits blood coagulation by enhancing the activity of antithrombin III, which inactivates thrombin and other clotting factors. - Standard anticoagulation · Faculty Hospital Kralovske Vinohrady · Cardiovascular
Standard anticoagulation prevents blood clot formation by inhibiting coagulation cascade factors, reducing thrombotic events. - No low molecular weight heparin · Beijing Anzhen Hospital · Cardiovascular
No low molecular weight heparin works by inhibiting Factor Xa and thrombin.
Phase 3 pipeline (15)
- Continuous heparin infusion · Yong Seog Oh · Cardiovascular
Heparin is an anticoagulant that inhibits multiple clotting factors to prevent thrombus formation. - Heparin, Low-Molecular-Weight · National and Kapodistrian University of Athens · Cardiovascular
Low-molecular-weight heparin inhibits blood coagulation by enhancing the activity of antithrombin III, which inactivates clotting factors Xa and IIa. - Low Heparin Molecular Weight · University Hospital, Angers · Cardiovascular
Low molecular weight heparin (LMWH) inhibits blood coagulation by enhancing the activity of antithrombin III, which inactivates clotting factors Xa and IIa. - Heparin - Therapeutic dosage · University of Sao Paulo · Cardiovascular
Heparin inhibits blood coagulation by potentiating antithrombin III, which inactivates thrombin and other clotting factors. - Unfractioned heparin · Universidad de Antioquia · Cardiovascular
Unfractionated heparin works by activating antithrombin, a protein that inhibits the coagulation cascade. - Prevention of Venous Thromboembolism · Prof. Stavros Konstantinides, MD · Cardiovascular
This drug prevents the formation of blood clots in the veins by inhibiting the coagulation cascade. - Plasma-derived antithrombin · Kyowa Kirin Co., Ltd. · Cardiovascular
Plasma-derived antithrombin is a protein that inhibits the coagulation cascade by binding to and neutralizing thrombin and other coagulation factors. - Therapeutic Anticoagulation · Unity Health Toronto · Cardiovascular
Therapeutic anticoagulation involves the inhibition of blood clot formation to prevent thrombotic events. - low molecular weight heparin, 5-FU · Shahid Beheshti University of Medical Sciences · Cardiovascular
Low molecular weight heparin works by inhibiting Factor Xa and thrombin, preventing blood clot formation. - Heparin - Prophylactic dosage · University of Sao Paulo · Cardiovascular
Heparin inhibits blood coagulation by potentiating antithrombin III, which inactivates thrombin and other clotting factors to prevent clot formation. - Conventional low dose thromboprophylaxis · UMC Utrecht · Cardiovascular
Conventional low-dose thromboprophylaxis prevents blood clot formation by inhibiting coagulation cascade factors, typically using anticoagulants at reduced doses for prevention rather than treatment. - (LMW)heparin · Sanofi · Cardiovascular
Low-molecular-weight heparin inhibits blood coagulation by enhancing the activity of antithrombin III, which inactivates clotting factors Xa and IIa. - UFH (unfractionated heparin) · Assistance Publique - Hôpitaux de Paris · Cardiovascular
UFH inhibits blood coagulation by enhancing the activity of antithrombin III, which inactivates thrombin and other clotting factors. - Intermittent heparin infusion · Yong Seog Oh · Cardiovascular
Intermittent heparin infusion prevents blood clot formation by inhibiting thrombin and other coagulation factors through periodic intravenous administration. - sham mPENTOCLO · Sunnybrook Health Sciences Centre · Cardiovascular
Pentosan polysulfate sodium is an anticoagulant that works by inhibiting the coagulation cascade.
Phase 2 pipeline (3)
- Du-Cotecxin · London School of Hygiene and Tropical Medicine · Cardiovascular
Du-Cotecxin is a heparin-based anticoagulant. - Enoxaparin Sodium Injection; Rivaroxaban Tablets · Beijing Suncadia Pharmaceuticals Co., Ltd · Cardiovascular
Enoxaparin sodium injection works by inhibiting Factor Xa and Factor IIa, preventing blood clot formation, while rivaroxaban tablets inhibit Factor Xa directly. - Anticoagulation treatment. · Samsung Medical Center · Cardiovascular
Anticoagulation via inhibition of vitamin K-dependent clotting factors