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Standard dose heparin

San Filippo Neri General Hospital · FDA-approved active Small molecule Under review Quality 0/100

Standard dose heparin is a Anticoagulant Small molecule drug developed by San Filippo Neri General Hospital. It is currently FDA-approved for Acute venous thromboembolism (deep vein thrombosis and pulmonary embolism) treatment and prevention, Acute coronary syndrome, Atrial fibrillation for stroke prevention. Also known as: 100 Ui/Kg bolus heparin.

Heparin inhibits blood coagulation by enhancing the activity of antithrombin III, which inactivates thrombin and other clotting factors.

Standard dose heparin is used to treat conditions such as Venous Thromboembolic Event, Aneurysm, and Limb Ischemia, as well as to prevent complications in patients with Diffuse Large B Cell Lymphoma. It works by activating Antithrombin-III, a protein that inhibits blood clotting.

At a glance

Generic nameStandard dose heparin
Also known as100 Ui/Kg bolus heparin
SponsorSan Filippo Neri General Hospital
Drug classAnticoagulant
TargetAntithrombin III (enhancer); indirect inhibition of thrombin and Factor Xa
ModalitySmall molecule
Therapeutic areaCardiovascular
PhaseFDA-approved

Mechanism of action

Heparin is an anticoagulant that works by binding to antithrombin III and dramatically increasing its ability to inactivate thrombin (Factor IIa) and Factor Xa. This prevents the formation of fibrin clots and the extension of existing clots. Standard (unfractionated) heparin has a rapid onset of action and is administered intravenously or subcutaneously.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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Frequently asked questions about Standard dose heparin

What is Standard dose heparin?

Standard dose heparin is a Anticoagulant drug developed by San Filippo Neri General Hospital, indicated for Acute venous thromboembolism (deep vein thrombosis and pulmonary embolism) treatment and prevention, Acute coronary syndrome, Atrial fibrillation for stroke prevention.

How does Standard dose heparin work?

Heparin inhibits blood coagulation by enhancing the activity of antithrombin III, which inactivates thrombin and other clotting factors.

What is Standard dose heparin used for?

Standard dose heparin is indicated for Acute venous thromboembolism (deep vein thrombosis and pulmonary embolism) treatment and prevention, Acute coronary syndrome, Atrial fibrillation for stroke prevention, Prevention of thrombosis during cardiac surgery and extracorporeal circulation.

Who makes Standard dose heparin?

Standard dose heparin is developed and marketed by San Filippo Neri General Hospital (see full San Filippo Neri General Hospital pipeline at /company/san-filippo-neri-general-hospital).

Is Standard dose heparin also known as anything else?

Standard dose heparin is also known as 100 Ui/Kg bolus heparin.

What drug class is Standard dose heparin in?

Standard dose heparin belongs to the Anticoagulant class. See all Anticoagulant drugs at /class/anticoagulant.

What development phase is Standard dose heparin in?

Standard dose heparin is FDA-approved (marketed).

What are the side effects of Standard dose heparin?

Common side effects of Standard dose heparin include Bleeding, Heparin-induced thrombocytopenia (HIT), Thrombosis, Osteoporosis (with prolonged use), Hyperkalemia.

What does Standard dose heparin target?

Standard dose heparin targets Antithrombin III (enhancer); indirect inhibition of thrombin and Factor Xa and is a Anticoagulant.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing