NYU Langone Health

Quick facts

Marketed products

• ACB · Cardiovascular
  ACB is an anticoagulant that works by inhibiting Factor Xa.
• Acthar high dose (80 U) · Immunology / Rheumatology / Neurology
  Acthar is a synthetic adrenocorticotropic hormone (ACTH) that stimulates the adrenal cortex to produce and release cortisol and other corticosteroids.
• Acthar low dose (40 U) · Immunology
  Acthar is a synthetic adrenocorticotropic hormone (ACTH) that stimulates the adrenal cortex to produce and release cortisol and other corticosteroids.
• Adderall ® Immediate Release · Neurology / Psychiatry
  Adderall is a combination of amphetamine salts that increases the release and blocks the reuptake of dopamine and norepinephrine in the central nervous system, enhancing focus and attention.
• Adderall XR ®
• Ankle OnQ · Pain Management / Orthopedic Surgery
  Ankle OnQ is a continuous peripheral nerve block catheter system that delivers local anesthetic directly to nerve tissue around the ankle to provide prolonged postoperative pain relief.
• Ankle SSB
• Anti-ADHD medication
• Aspirin and/or Atorvastatin · Cardiovascular
  Aspirin inhibits platelet aggregation via COX inhibition, while atorvastatin reduces cholesterol synthesis by inhibiting HMG-CoA reductase, together reducing cardiovascular risk.
• Atorvastatin Calcium Tablets
• Barbotage · Other
• Blood laboratory tests
• Bupivacaine (Marcaine) · Anesthesia
  Bupivacaine blocks sodium channels in nerve cell membranes, preventing the initiation and propagation of action potentials to produce local anesthesia.
• CpG-adjuvanted HBV Vaccine
• DR OnQ
• DR SSB
• Evolocumab Cartridge
• Extended-Release Buprenorphine Injection
• Ezetimibe Tablets
• Ioxaglate · Other
• IPACK block · Anesthesia/Pain Management
  IPACK block is a regional anesthesia technique that combines infiltration of the interspace between the popliteal artery and capsule of the knee joint with a popliteal sciatic nerve block to provide perioperative analgesia for knee surgery.
• LDX Treatment · Psychiatry / Neurology
  LDX (lisdexamfetamine) is a prodrug that is metabolized to d-amphetamine, which increases the release and blocks the reuptake of norepinephrine and dopamine in the central nervous system.
• Lidocaine Hydrochloride with Epinephrine
• Marcaine, Duramorph , ketorolac
• Masked Oral Valacyclovir · Infectious Disease / Virology
  Masked oral valacyclovir is a taste-masked formulation of valacyclovir that inhibits viral DNA polymerase to prevent herpes simplex virus and varicella-zoster virus replication.
• MTX therapy · Oncology, Immunology, Rheumatology
  Methotrexate inhibits dihydrofolate reductase, blocking folate metabolism and reducing DNA synthesis and cell proliferation.
• MYDAYIS · Other
  mydayis works by interacting with a specific target in the body to produce a desired effect.
• Nebulized 3% sodium chloride solution · Pulmonology/Respiratory
  Nebulized hypertonic saline draws fluid into the airways through osmotic gradient, hydrating secretions and promoting mucus clearance.
• oral escitalopram · Psychiatry / Mental Health
  Escitalopram selectively inhibits the reuptake of serotonin at the neuronal synapse, increasing serotonin availability in the brain.
• Oral Naltrexone (O-NTX) · Psychiatry / Addiction Medicine
  Oral naltrexone is an opioid receptor antagonist that blocks opioid signaling in the central and peripheral nervous system.
• Palonosetron only · Oncology / Supportive Care
  Palonosetron is a highly selective 5-HT3 receptor antagonist that blocks serotonin signaling in the chemoreceptor trigger zone and gastrointestinal tract to prevent nausea and vomiting.
• Palonosetron with Dexamethasone
• PiB · Neurology / Alzheimer's Disease
  PiB (Pittsburgh Compound B) is a positron emission tomography (PET) tracer that binds to amyloid-beta plaques in the brain to enable imaging and detection of amyloid pathology.
• Placebo Pills · Multiple (symptom-dependent; commonly pain, nausea, fatigue)
  Placebo pills produce therapeutic effects through the patient's expectation and belief that they will work, activating endogenous healing mechanisms.
• Preventative Medication (PM) · Cardiovascular
  Prevents cardiovascular events by inhibiting platelet aggregation.
• Propofol/Lidocaine · Anesthesiology
  Propofol and lidocaine together provide rapid induction and maintenance of anesthesia with reduced pain on injection through synergistic central nervous system depression.
• Recombinant Human Thrombin
• Serdexmethylphenidate/dexmethylphenidate · Neurology/Psychiatry
  Serdexmethylphenidate is a prodrug that is metabolized to dexmethylphenidate, which inhibits the reuptake of dopamine and norepinephrine in the central nervous system.
• Sublingual Buprenorphine (SLB) · Addiction Medicine / Pain Management
  Buprenorphine is a partial mu-opioid receptor agonist that binds with high affinity to opioid receptors in the brain, reducing cravings and withdrawal symptoms while producing a ceiling effect on respiratory depression.
• Tc-99m Pentetate · Diagnostic Imaging / Nuclear Medicine
  Tc-99m Pentetate is a radiopharmaceutical that binds to transferrin in the blood and is filtered by the kidneys, allowing visualization of renal function and urinary tract anatomy via nuclear imaging.

Phase 3 pipeline

• Albuterol-sulphate · Respiratory
  Albuterol sulfate is a beta-2 adrenergic agonist that binds to beta-2 receptors on airway smooth muscle, causing relaxation and bronchodilation.
• AT-001 · Cardiovascular
  AT-001 is an antisense oligonucleotide that reduces production of lipoprotein(a) by targeting hepatic apolipoprotein(a) synthesis.
• Botulinum Toxin commonly known as BOTOX® · Neurology; Aesthetics; Pain Management
  Botulinum toxin blocks the release of acetylcholine at the neuromuscular junction by cleaving SNARE proteins, causing temporary muscle paralysis.
• Continuous ketamine infusion · Psychiatry / Mental Health
  Ketamine blocks NMDA glutamate receptors in the brain, rapidly reducing depressive symptoms through dissociative and neuromodulatory effects.
• Nicotine Replacement Therapy Agent - Gum · Smoking Cessation / Addiction Medicine
  Nicotine gum delivers nicotine through oral mucosa absorption to replace nicotine from cigarettes and reduce withdrawal symptoms during smoking cessation.
• Nicotine Replacement Therapy Agent - Lozenges · Addiction
  Lozenges release nicotine into the bloodstream to help manage withdrawal symptoms and cravings.
• Nicotine Replacement Therapy Agent - Patches · Addiction Medicine / Smoking Cessation
  Nicotine patches deliver nicotine transdermally to bind nicotinic acetylcholine receptors in the brain, reducing withdrawal symptoms and cravings during smoking cessation.
• Ortho-Novum 777 · Contraception / Gynecology
  Ortho-Novum 777 is a triphasic oral contraceptive that prevents pregnancy through hormonal suppression of ovulation.

Phase 2 pipeline

• aerosol interferon-gamma
• Bacteriophage Treatment · Infectious Disease
  Bacteriophages selectively infect and kill bacteria
• Carbidopa High-Dose · Movement Disorders
  Carbidopa is a decarboxylase inhibitor that prevents the conversion of levodopa to dopamine, thereby increasing the availability of levodopa in the brain.
• Carbidopa Low-Dose · Neurology
  Carbidopa is a decarboxylase inhibitor that prevents the conversion of levodopa to dopamine, thereby increasing the availability of levodopa in the brain.
• Dexmedetomidine Sublingual · Neurology
  Alpha-2 adrenergic receptor agonist
• FGF-2 · Cardiovascular
  FGF-2 is a fibroblast growth factor that promotes angiogenesis and tissue repair.
• flecainide iv
• Fluticasone propionate HFA 220
• Induction Chemo-Immunotherapy · Oncology
  Induction of anti-tumor immune response through chemo-immunotherapy
• Leuprolide, Degarelix or Relugolix
• Levetiracetam Pill
• liposomal interleukin-2
• liposomal NDDP
• Lisinopril, losartan, and atorvastatin
• MRI Tracer
• PET Tracer
• polyvalent melanoma vaccine
• Rocuronium Bromide, Cisatracurium Besylate
• SAM-e
• SL-BUP
• Subcutaneous interferon-gamma
• XR-BUP

Phase 1 pipeline

• 89Zr-DFO-girentuximab · Oncology
  Targeting CD22
• Autologous cytokines
• CpG1018
• Dexamethasone or other corticosteroid
• Ferric carboxymaltose infusion
• Hormone Suppressors
• Montanide · Other
• synovial fluid biomarker concentrations
• Vaginal estrogen tablet

Competitive intelligence

For the full portfolio CI brief — phase mix, recent regulatory actions, upcoming PDUFA dates, patent timeline, class-overlap with competitors:

• NYU Langone Health portfolio CI brief
• NYU Langone Health pipeline updates RSS

Frequently asked questions about NYU Langone Health

Related

• ACB · Cardiovascular
• Acthar high dose (80 U) · Immunology / Rheumatology / Neurology
• Acthar low dose (40 U) · Immunology
• Adderall ® Immediate Release · Neurology / Psychiatry
• Adderall XR ®
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