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FGF-2
FGF-2 is a fibroblast growth factor that promotes angiogenesis and tissue repair.
FGF-2 is a fibroblast growth factor that promotes angiogenesis and tissue repair. Used for Cardiac repair and regeneration.
At a glance
| Generic name | FGF-2 |
|---|---|
| Also known as | FGF2, Human Fibroblast Growth Factor 2 |
| Sponsor | NYU Langone Health |
| Target | FGFR1 |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular |
| Phase | Phase 2 |
Mechanism of action
FGF-2 works by binding to its receptor, FGFR1, to stimulate the growth of new blood vessels and promote the healing of damaged tissues. This process is crucial for wound repair and tissue regeneration. Additionally, FGF-2 has been shown to have anti-inflammatory properties, which may contribute to its therapeutic effects.
Approved indications
- Cardiac repair and regeneration
Common side effects
- Injection site reaction
Key clinical trials
- Evaluation of Albumin Platelet-Rich Fibrin Following SRP in Patients With Periodontitis (NA)
- Fibroblast Growth Factor Regeneration of Tympanic Membrane Perforations (PHASE2)
- In-office Repair of Chronic Tympanic Membrane Perforations (PHASE1, PHASE2)
- Fibroblast Growth Factor Regeneration of Tympanic Membrane Perforations (PHASE2)
- Lymphedema Surveillance Study
- The Application of Bovine Basic Fibroblast Growth Factor Gel in the Treatment of Sensitive Skin (NA)
- Evaluation of RC28-E Injection in Diabetic Macular Edema (PHASE2)
- Randomized Phase IIb Trial of DVC1-0101 (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |