Progestin
This page covers all Progestin drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Glucocorticoid receptor, Progesterone receptor, Progesterone receptor (PR).
Targets
Glucocorticoid receptor · Progesterone receptor · Progesterone receptor (PR) · Mineralocorticoid receptor · GnRH receptors · Corticosteroid-binding globulin · Amine oxidase [flavin-containing] A · Sex hormone-binding globulin · Progesterone receptor; mineralocorticoid receptor antagonist
Marketed (20)
- Megace · Bristol-Myers Squibb · Oncology
- Jadelle · Fdn Consumer · Bone
Jadelle works by binding to the progesterone receptor, which helps to prevent ovulation and thicken cervical mucus to prevent sperm from reaching the egg. - Provera (medroxyprogesterone) · University Hospital of North Norway · Gynecology/Contraception
Medroxyprogesterone is a synthetic progestin that binds to progesterone receptors to suppress ovulation and alter the endometrium. - Medroxyprogesterone 17-Acetate · Women's Health Care Clinic, Torrance, California · Women's Health / Contraception / Hormone Replacement
Medroxyprogesterone acetate is a synthetic progestin that suppresses gonadotropin-releasing hormone (GnRH) and inhibits ovulation by acting on the hypothalamic-pituitary-ovarian axis. - Norethindrone acetate (NTA) · Baylor Research Institute · Contraception, Gynecology, Endocrinology
Norethindrone acetate is a synthetic progestin that binds to progesterone receptors to suppress ovulation and alter the endometrium for contraceptive and hormonal therapy effects. - Dydrogesterone Oral Tablet · Kasr El Aini Hospital · Obstetrics and Gynecology
Dydrogesterone is a synthetic progestin that binds to progesterone receptors to support luteal phase function and maintain pregnancy. - Vaginal micronized progesterone · Instituto Valenciano de Infertilidade de Lisboa · Reproductive/Fertility
Micronized progesterone administered vaginally binds to progesterone receptors to support luteal phase function and maintain early pregnancy. - Slynd · Exeltis Usa Inc · Dermatology
Slynd works by binding to the mineralocorticoid receptor, a protein that plays a role in hormone regulation. - Vaginal Progesteron · Omar Mamdouh Shaaban · Obstetrics/Gynecology
Vaginal progesterone delivers the hormone progesterone directly to the reproductive tract to support luteal phase function and maintain early pregnancy. - Oral Dienogest · Bio Meds Pharmaceutica Ltda · Gynecology
Dienogest is a synthetic progestin that suppresses ovulation and alters the endometrium to treat endometriosis. - Micronor · Johnson & Johnson · Bone
ORIAHNN combines elagolix, which suppresses LH and FSH to reduce ovarian sex hormones, with estradiol and norethindrone acetate to mitigate side effects. - Natazia · Mochida Pharmaceutical Co., Ltd. · Other
Natazia works by binding to the progesterone receptor in the body, mimicking the effects of the natural hormone progesterone. - Delalutin · Bristol-Myers Squibb · Oncology
- Dydrogesterone M ( case 2 ) · Trieu, Nguyen Thi, M.D. · Obstetrics/Gynecology
Dydrogesterone is a synthetic progestin that binds to progesterone receptors to support luteal phase function and maintain pregnancy. - Dydrogesterone M ( case 1 ) · Trieu, Nguyen Thi, M.D. · Obstetrics/Gynecology
Dydrogesterone is a synthetic progestin that binds to progesterone receptors to support luteal phase function and maintain pregnancy. - Vaginal Progesterone · University of North Carolina, Chapel Hill · Obstetrics/Gynecology
Vaginal progesterone supplements the natural hormone progesterone to support and maintain pregnancy by promoting endometrial secretion and reducing uterine contractility. - Oral micronized progesterone · University of British Columbia · Obstetrics/Gynecology
Oral micronized progesterone acts as a progestin that binds to progesterone receptors in the uterus and other reproductive tissues to regulate the menstrual cycle and support pregnancy. - Progesterone Vaginal Product · UMC Utrecht · Reproductive Health / Obstetrics
Progesterone binds to progesterone receptors in the reproductive tract to support luteal phase function and maintain pregnancy. - Ethinodiol · Other
- Ortho-Cept · Merck & Co. · Other
Phase 3 pipeline (6)
- Progesterone Effervescent Vaginal Tablets · University of Alberta · Reproductive Health / Obstetrics
Progesterone is a naturally occurring steroid hormone that binds to progesterone receptors to support luteal phase function and maintain pregnancy. - Micronised vaginal progesterone · National University of Malaysia · Obstetrics and Gynecology
Micronised vaginal progesterone works by releasing progesterone locally in the vagina to prevent preterm birth. - LF111 (drospirenone) · Laboratories Leon Farma, S.A. · Contraception / Gynecology
Drospirenone is a progestin that acts as a progesterone receptor agonist and aldosterone antagonist, used in hormonal contraceptive formulations. - Progesterone-IBSA Injectable Solution · IBSA Institut Biochimique SA · Obstetrics/Gynecology
Progesterone binds to progesterone receptors in the uterus and other reproductive tissues to maintain pregnancy and regulate the menstrual cycle. - Levonorgestrel (BAY98-7196) · Bayer · Contraception
Levonorgestrel is a synthetic progestin that prevents pregnancy by suppressing ovulation and altering cervical mucus and endometrial conditions. - Norethindrone Acetate (NA) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · Reproductive Health / Contraception
Norethindrone acetate is a synthetic progestin that suppresses the luteinizing hormone surge and inhibits ovulation by acting on the hypothalamic-pituitary-ovarian axis.
Phase 1 pipeline (1)
- Additional vaginal progesterone · Hillel Yaffe Medical Center · Gynecology
Progesterone acts on the progesterone receptor.