Mineralocorticoid receptor — Drug Target

All drugs that target Mineralocorticoid receptor — marketed and clinical-stage. Includes 8 drug classes acting on this target.

Drug classes

Nonsteroidal Mineralocorticoid-Receptor Antagonist [EPC] · canrenone · fludrocortisone · Progestin · desoxycorticosterone acetate · desoxycorticosterone pivalate · Aldosterone Antagonist [EPC] · Mineralocorticoid receptor antagonist

Marketed (8)

• Kerendia · Bayer · Nonsteroidal Mineralocorticoid-Receptor Antagonist [EPC] · Metabolic
  Kerendia works by blocking the mineralocorticoid receptor, a protein that regulates sodium and potassium levels in the body.
• Aldadiene · canrenone · Other
• Minnebro · Daiichi Sankyo · Metabolic
• Florinef · fludrocortisone · Hematology
• Slynd · Exeltis Usa Inc · Progestin · Dermatology
  Slynd works by binding to the mineralocorticoid receptor, a protein that plays a role in hormone regulation.
• Sincortex · Merck & Co. · desoxycorticosterone acetate · Other
• Deoxycortone Pivalate · Novartis · desoxycorticosterone pivalate · Hematology
• Inspra · Upjohn · Aldosterone Antagonist [EPC] · Cardiovascular
  Inspra works by blocking the action of aldosterone, a hormone that can cause the body to retain too much salt and water.

Phase 2 pipeline (1)

• HF medication · Bayer · Mineralocorticoid receptor antagonist · Cardiovascular
  Blocks the action of aldosterone