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Micronised vaginal progesterone
Micronised vaginal progesterone works by releasing progesterone locally in the vagina to prevent preterm birth.
Micronised vaginal progesterone works by releasing progesterone locally in the vagina to prevent preterm birth. Used for Prevention of preterm birth in women at risk.
At a glance
| Generic name | Micronised vaginal progesterone |
|---|---|
| Also known as | Utrogestan |
| Sponsor | National University of Malaysia |
| Drug class | Progestin |
| Modality | Small molecule |
| Therapeutic area | Obstetrics and Gynecology |
| Phase | Phase 3 |
Mechanism of action
Progesterone is a hormone that helps maintain pregnancy. By releasing it locally in the vagina, micronised vaginal progesterone helps to reduce the risk of preterm birth by promoting the growth and development of the fetus.
Approved indications
- Prevention of preterm birth in women at risk
Common side effects
- Vaginal discharge
- Vaginal bleeding
- Headache
Key clinical trials
- Comparison Between Vaginal Pessary and Progestogen in Twin Pregnancy With Short Cervical Length (PHASE3)
- Randomized Controlled Trial of Vaginal Progesterone in Women With Threatened Preterm Labor (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |