{"id":"micronised-vaginal-progesterone","safety":{"commonSideEffects":[{"rate":"null","effect":"Vaginal discharge"},{"rate":"null","effect":"Vaginal bleeding"},{"rate":"null","effect":"Headache"}]},"_chembl":{"chemblId":"CHEMBL103","moleculeType":"Small molecule","molecularWeight":"314.47"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Progesterone is a hormone that helps maintain pregnancy. By releasing it locally in the vagina, micronised vaginal progesterone helps to reduce the risk of preterm birth by promoting the growth and development of the fetus.","oneSentence":"Micronised vaginal progesterone works by releasing progesterone locally in the vagina to prevent preterm birth.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:49:57.067Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of preterm birth in women at risk"}]},"trialDetails":[{"nctId":"NCT04342585","phase":"PHASE3","title":"Comparison Between Vaginal Pessary and Progestogen in Twin Pregnancy With Short Cervical Length","status":"COMPLETED","sponsor":"National University of Malaysia","startDate":"2019-10-01","conditions":"Preterm Birth","enrollment":142},{"nctId":"NCT01286246","phase":"PHASE4","title":"Randomized Controlled Trial of Vaginal Progesterone in Women With Threatened Preterm Labor","status":"TERMINATED","sponsor":"University of Calgary","startDate":"2011-01","conditions":"Obstetric Labor, Premature","enrollment":34}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Utrogestan"],"phase":"phase_3","status":"active","brandName":"Micronised vaginal progesterone","genericName":"Micronised vaginal progesterone","companyName":"National University of Malaysia","companyId":"national-university-of-malaysia","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Micronised vaginal progesterone works by releasing progesterone locally in the vagina to prevent preterm birth. Used for Prevention of preterm birth in women at risk.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}