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Dydrogesterone Oral Tablet

Kasr El Aini Hospital · FDA-approved active Small molecule

Dydrogesterone Oral Tablet is a Progestin Small molecule drug developed by Kasr El Aini Hospital. It is currently FDA-approved for Luteal phase support and progesterone supplementation, Threatened or habitual miscarriage, Menstrual disorders and irregular menstruation. Also known as: Duphaston, Duphastone (Solvay Pharmaceuticals), OD, Placebo OD.

Dydrogesterone is a synthetic progestin that binds to progesterone receptors to support luteal phase function and maintain pregnancy.

Dydrogesterone is a synthetic progestin that binds to progesterone receptors to support luteal phase function and maintain pregnancy. Used for Luteal phase support and progesterone supplementation, Threatened or habitual miscarriage, Menstrual disorders and irregular menstruation.

At a glance

Generic nameDydrogesterone Oral Tablet
Also known asDuphaston, Duphastone (Solvay Pharmaceuticals), OD, Placebo OD
SponsorKasr El Aini Hospital
Drug classProgestin
TargetProgesterone receptor
ModalitySmall molecule
Therapeutic areaObstetrics and Gynecology
PhaseFDA-approved

Mechanism of action

Dydrogesterone is a retro-isomer of norgestrel that selectively activates progesterone receptors with minimal androgenic activity. It is used to supplement or replace endogenous progesterone in conditions of progesterone deficiency, particularly during the luteal phase of the menstrual cycle and in early pregnancy support. The drug helps maintain the endometrium and prevent uterine contractions necessary for pregnancy continuation.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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Frequently asked questions about Dydrogesterone Oral Tablet

What is Dydrogesterone Oral Tablet?

Dydrogesterone Oral Tablet is a Progestin drug developed by Kasr El Aini Hospital, indicated for Luteal phase support and progesterone supplementation, Threatened or habitual miscarriage, Menstrual disorders and irregular menstruation.

How does Dydrogesterone Oral Tablet work?

Dydrogesterone is a synthetic progestin that binds to progesterone receptors to support luteal phase function and maintain pregnancy.

What is Dydrogesterone Oral Tablet used for?

Dydrogesterone Oral Tablet is indicated for Luteal phase support and progesterone supplementation, Threatened or habitual miscarriage, Menstrual disorders and irregular menstruation, Endometriosis.

Who makes Dydrogesterone Oral Tablet?

Dydrogesterone Oral Tablet is developed and marketed by Kasr El Aini Hospital (see full Kasr El Aini Hospital pipeline at /company/kasr-el-aini-hospital).

Is Dydrogesterone Oral Tablet also known as anything else?

Dydrogesterone Oral Tablet is also known as Duphaston, Duphastone (Solvay Pharmaceuticals), OD, Placebo OD.

What drug class is Dydrogesterone Oral Tablet in?

Dydrogesterone Oral Tablet belongs to the Progestin class. See all Progestin drugs at /class/progestin.

What development phase is Dydrogesterone Oral Tablet in?

Dydrogesterone Oral Tablet is FDA-approved (marketed).

What are the side effects of Dydrogesterone Oral Tablet?

Common side effects of Dydrogesterone Oral Tablet include Headache, Dizziness, Nausea, Breast tenderness, Abdominal discomfort.

What does Dydrogesterone Oral Tablet target?

Dydrogesterone Oral Tablet targets Progesterone receptor and is a Progestin.

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