What are Anticholinergic antispasmodic drugs?

Anticholinergic antispasmodic drugs are pharmacologic agents that share a common mechanism (typically targeting Muscarinic acetylcholine receptors (M1-M5)). 5 are currently marketed, with 6 more in clinical development.

What are the marketed Anticholinergic antispasmodic drugs?

Marketed Anticholinergic antispasmodic drugs include hyoscine-N-butyl bromide(HBB), Cantabell Tab, anti spasmodic agents, DICYCLOMINE, alverine citrate and simeticone.

Anticholinergic antispasmodic

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

5 marketed 5 in Phase 3 1 in Phase 1

This page covers all Anticholinergic antispasmodic drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Muscarinic acetylcholine receptors (M1-M5), Muscarinic acetylcholine receptors, Muscarinic receptors.

Targets

Muscarinic acetylcholine receptors (M1-M5) · Muscarinic acetylcholine receptors · Muscarinic receptors · Phosphodiesterase; calcium channels · Calcium channels (L-type); smooth muscle relaxant · Acetylcholine receptor

Marketed (5)

hyoscine-N-butyl bromide(HBB) · Sisli Hamidiye Etfal Training and Research Hospital · Gastroenterology
Hyoscine-N-butyl bromide is an anticholinergic agent that blocks muscarinic acetylcholine receptors to reduce smooth muscle spasms and secretions.
Cantabell Tab · Chong Kun Dang Pharmaceutical · Gastroenterology / Urology
Cantabell is an antispasmodic agent that relaxes smooth muscle in the gastrointestinal and urinary tracts by blocking muscarinic acetylcholine receptors.
anti spasmodic agents · Laboratoires Mayoly Spindler · Gastroenterology
Antispasmodic agents reduce muscle contractions and spasms by inhibiting smooth muscle contraction in the gastrointestinal tract and other organs.
DICYCLOMINE · Gastroenterology
Dicyclomine relieves smooth muscle spasm of the gastrointestinal tract via a dual mechanism: anticholinergic effects at acetylcholine receptors and direct smooth muscle relaxation.
alverine citrate and simeticone · Laboratoires Mayoly Spindler · Gastroenterology
Alverine citrate is a smooth muscle relaxant that reduces intestinal spasms, while simeticone is an anti-foaming agent that reduces gas bloating.

Phase 3 pipeline (5)

Ileocolonic release peppermint oil · Maastricht University Medical Center · Gastroenterology
Ileocolonic release peppermint oil delivers peppermint oil directly to the ileum and colon, where it exerts antispasmodic and anti-inflammatory effects on the lower gastrointestinal tract.
Mebeverine+Simethicone · Abbott · Gastroenterology
Mebeverine relaxes smooth muscle in the gastrointestinal tract while simethicone reduces gas bloating by breaking down gas bubbles.
Phloroglucin(Flospan®) · Keimyung University Dongsan Medical Center · Gastroenterology
Phloroglucin acts as a smooth muscle relaxant and antispasmodic agent by inhibiting phosphodiesterase and modulating calcium channels in visceral smooth muscle.
Hyoscine butylbromide, Analgesics, Non-Narcotic · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Gastroenterology
Hyoscine butylbromide is an anticholinergic agent that blocks muscarinic acetylcholine receptors to reduce smooth muscle spasms and secretions.
Colpermin® · Shiraz University of Medical Sciences · Gastroenterology
Colpermin is a peppermint oil-based formulation that acts as an antispasmodic agent to reduce smooth muscle contractions in the gastrointestinal tract.

Phase 1 pipeline (1)

A standard antispasmodic · S.LAB (SOLOWAYS) · Gastroenterology
Blocks acetylcholine receptors to relax smooth muscle

Patent intelligence

antispasmodic patent landscape — aggregated cliff calendar, attackable patents, originator estates