muscarinic receptors — Drug Target

All drugs that target muscarinic receptors — marketed and clinical-stage. Includes 4 drug classes acting on this target.

Drug classes

aceclidine · Antispasmodic and anticholinergic (antimuscarinic) agent · Anticholinergic · anticholinergic

Marketed (3)

• Aceclidin · aceclidine · Neuroscience
  VIZZ, a pupil-selective miotic, contracts the iris sphincter muscle to improve vision by extending depth of focus.
• DICYCLOMINE · Antispasmodic and anticholinergic (antimuscarinic) agent · Gastroenterology
  Dicyclomine relieves smooth muscle spasm of the gastrointestinal tract via a dual mechanism: anticholinergic effects at acetylcholine receptors and direct smooth muscle relaxation.
• SOLIFENACIN SUCCINATE
  Solifenacin blocks muscarinic receptors, reducing urinary bladder smooth muscle contractions.

Phase 3 pipeline (1)

• Tropicamide Ophthalmic · Semnan University of Medical Sciences · Anticholinergic · Ophthalmology
  Tropicamide Ophthalmic is an anticholinergic agent that works by blocking muscarinic receptors in the eye to induce mydriasis and cycloplegia.

Phase 2 pipeline (2)

• Glycopyrronium MDI · Pearl Therapeutics, Inc. · Anticholinergic · Respiratory
  Anticholinergic
• A-101 Solution 40 · Aclaris Therapeutics, Inc. · anticholinergic · Dermatology
  A-101 Solution 40 is a topical solution used to treat hyperhidrosis.