Last reviewed 2026-04-23 · How we verify

Tropicamide Ophthalmic

Tropicamide Ophthalmic is an anticholinergic agent that works by blocking muscarinic receptors in the eye to induce mydriasis and cycloplegia.

Tropicamide Ophthalmic is an anticholinergic agent that works by blocking muscarinic receptors in the eye to induce mydriasis and cycloplegia. Used for Induction of mydriasis and cycloplegia for ophthalmic examinations.

At a glance

Mechanism of action

By blocking muscarinic receptors, tropicamide Ophthalmic reduces the parasympathetic tone on the iris sphincter muscle, leading to pupil dilation and paralysis of accommodation. This effect is reversible and typically lasts for several hours.

Approved indications

• Induction of mydriasis and cycloplegia for ophthalmic examinations

Common side effects

• Dry mouth
• Blurred vision
• Headache

Key clinical trials

• Comparison of 4 Methods of Eye Drops for Pupil Dilation in Diabetic Patients (NA)
• The Effect Of Polycystic Ovarian Syndrome Treatment On Ocular Surface.
• Chromosome 18 Clinical Research Center
• Adaptive Optics (AO) Analysis of Retinal Arteries in Patients With Recent Stroke (STROKAO)
• Clinical Determinants and Adverse Reactions to Tropicamide/Phenylephrine in Hospitalized Patients.
• Subthreshold Micropulse Laser Therapy (SML) in Retinitis Pigmentosa (NA)
• Pharmacodynamics of a Fixed Dose Combination of 0.34% Tropicamide and 2.5% Phenylephrine Hydrochloride, Eye Drop, Solution (PHASE1, PHASE2)
• Retinal Vascular Changes in Patients After Coronavirus Disease 2019 (COVID-19)

Primary sources

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