Last reviewed · How we verify
hyoscine-N-butyl bromide(HBB)
hyoscine-N-butyl bromide(HBB) is a Anticholinergic antispasmodic Small molecule drug developed by Sisli Hamidiye Etfal Training and Research Hospital. It is currently FDA-approved for Abdominal pain and cramping associated with irritable bowel syndrome, Gastrointestinal spasms, Urinary tract spasms and dysuria. Also known as: Molit amp..
Hyoscine-N-butyl bromide is an anticholinergic agent that blocks muscarinic acetylcholine receptors to reduce smooth muscle spasms and secretions.
Hyoscine-N-butyl bromide is an anticholinergic agent that blocks muscarinic acetylcholine receptors to reduce smooth muscle spasms and secretions. Used for Abdominal pain and cramping associated with irritable bowel syndrome, Gastrointestinal spasms, Urinary tract spasms and dysuria.
At a glance
| Generic name | hyoscine-N-butyl bromide(HBB) |
|---|---|
| Also known as | Molit amp. |
| Sponsor | Sisli Hamidiye Etfal Training and Research Hospital |
| Drug class | Anticholinergic antispasmodic |
| Target | Muscarinic acetylcholine receptors (M1-M5) |
| Modality | Small molecule |
| Therapeutic area | Gastroenterology |
| Phase | FDA-approved |
Mechanism of action
HBB competitively antagonizes muscarinic cholinergic receptors on smooth muscle in the gastrointestinal and urinary tracts, reducing involuntary contractions and spasms. As a quaternary ammonium compound, it is poorly absorbed systemically and acts primarily at peripheral sites, minimizing central nervous system effects. This results in antispasmodic and antisecretory effects useful in treating visceral pain and cramping.
Approved indications
- Abdominal pain and cramping associated with irritable bowel syndrome
- Gastrointestinal spasms
- Urinary tract spasms and dysuria
- Biliary colic
Common side effects
- Dry mouth
- Constipation
- Blurred vision
- Urinary retention
- Tachycardia
Key clinical trials
- How to Reduce Pain in Patients Undergoing Office Hysteroscopy. (NA)
- The Effect of Hyoscine-N-butylbromide (HBB, Buscopan) in Augmented Labour Among Primigravidae (PHASE4)
- Effect of Intravenous Hyoscine Butylbromide Injection on Labour in High Risk Women (PHASE4)
- Diclofenac Potassium Alone Versus Diclofenac Potassium With Hyoscine-N-butyl Bromide (HBB in Endoscopy (NA)
- Safety Study of Hyoscine N Butyl Bromide in Active Management of Labor (PHASE4)
- Does the Hyoscine N-Butylbromide Administered During Colonoscopy Increase the Adenoma Detection Rate? (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- hyoscine-N-butyl bromide(HBB) CI brief — competitive landscape report
- hyoscine-N-butyl bromide(HBB) updates RSS · CI watch RSS
- Sisli Hamidiye Etfal Training and Research Hospital portfolio CI
Frequently asked questions about hyoscine-N-butyl bromide(HBB)
What is hyoscine-N-butyl bromide(HBB)?
How does hyoscine-N-butyl bromide(HBB) work?
What is hyoscine-N-butyl bromide(HBB) used for?
Who makes hyoscine-N-butyl bromide(HBB)?
Is hyoscine-N-butyl bromide(HBB) also known as anything else?
What drug class is hyoscine-N-butyl bromide(HBB) in?
What development phase is hyoscine-N-butyl bromide(HBB) in?
What are the side effects of hyoscine-N-butyl bromide(HBB)?
What does hyoscine-N-butyl bromide(HBB) target?
Related
- Drug class: All Anticholinergic antispasmodic drugs
- Target: All drugs targeting Muscarinic acetylcholine receptors (M1-M5)
- Manufacturer: Sisli Hamidiye Etfal Training and Research Hospital — full pipeline
- Therapeutic area: All drugs in Gastroenterology
- Indication: Drugs for Abdominal pain and cramping associated with irritable bowel syndrome
- Indication: Drugs for Gastrointestinal spasms
- Indication: Drugs for Urinary tract spasms and dysuria
- Also known as: Molit amp.
- Compare: hyoscine-N-butyl bromide(HBB) vs similar drugs
- Pricing: hyoscine-N-butyl bromide(HBB) cost, discount & access