Last reviewed · How we verify
Ileocolonic release peppermint oil
Ileocolonic release peppermint oil delivers peppermint oil directly to the ileum and colon, where it exerts antispasmodic and anti-inflammatory effects on the lower gastrointestinal tract.
Ileocolonic release peppermint oil delivers peppermint oil directly to the ileum and colon, where it exerts antispasmodic and anti-inflammatory effects on the lower gastrointestinal tract. Used for Irritable bowel syndrome (IBS) with abdominal pain and cramping, Functional bowel disorder symptoms.
At a glance
| Generic name | Ileocolonic release peppermint oil |
|---|---|
| Sponsor | Maastricht University Medical Center |
| Drug class | Herbal antispasmodic agent |
| Modality | Small molecule |
| Therapeutic area | Gastroenterology |
| Phase | Phase 3 |
Mechanism of action
Peppermint oil contains menthol and other volatile compounds that act as calcium channel antagonists and smooth muscle relaxants. The ileocolonic release formulation uses enteric coating to protect the oil from gastric degradation, ensuring targeted delivery to the distal small intestine and colon where it can reduce visceral pain, bloating, and abnormal motility associated with functional bowel disorders.
Approved indications
- Irritable bowel syndrome (IBS) with abdominal pain and cramping
- Functional bowel disorder symptoms
Common side effects
- Heartburn or reflux
- Perianal burning
- Nausea
- Abdominal discomfort
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |