Muscarinic acetylcholine receptors — Drug Target

All drugs that target Muscarinic acetylcholine receptors — marketed and clinical-stage. Includes 7 drug classes acting on this target.

Drug classes

Anticholinergic antispasmodic · Anticholinergic muscle relaxant · Anticholinergic agent · Antimuscarinic agent · Anticholinergic [EPC] · Anticholinergic agent / Muscle relaxant · Anticholinergic

Marketed (6)

• Cantabell Tab · Chong Kun Dang Pharmaceutical · Anticholinergic antispasmodic · Gastroenterology / Urology
  Cantabell is an antispasmodic agent that relaxes smooth muscle in the gastrointestinal and urinary tracts by blocking muscarinic acetylcholine receptors.
• Postop oral orphenadrine · AdventHealth · Anticholinergic muscle relaxant · Pain Management / Musculoskeletal
  Orphenadrine is an anticholinergic agent that blocks muscarinic acetylcholine receptors to reduce muscle spasms and pain.
• Intravenous scopolamine hydrobromide · University of Iowa · Anticholinergic agent · Anesthesia and Perioperative Medicine
  Scopolamine is an anticholinergic agent that blocks muscarinic acetylcholine receptors to reduce secretions and motion-induced nausea.
• Enlon-Plus · Alcon Labs Inc · Antimuscarinic agent · Other
  Atropine antagonizes muscarine-like actions of acetylcholine through competitive antagonism at peripheral muscarinic receptors.
• SCOPOLAMINE · Anticholinergic [EPC] · Neuroscience
• Postop orphenadrine IV · AdventHealth · Anticholinergic agent / Muscle relaxant · Pain Management / Anesthesia
  Orphenadrine is an anticholinergic agent that blocks muscarinic acetylcholine receptors to reduce muscle spasms and provide analgesic effects.

Phase 3 pipeline (1)

• Hyoscine butylbromide, Analgesics, Non-Narcotic · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Anticholinergic antispasmodic · Gastroenterology
  Hyoscine butylbromide is an anticholinergic agent that blocks muscarinic acetylcholine receptors to reduce smooth muscle spasms and secretions.

Phase 2 pipeline (2)

• Dose 1 of glycopyrronium, 2.5% QD · Journey Medical Corporation · Anticholinergic · Ophthalmology
  Glycopyrronium is an anticholinergic that works by blocking the action of acetylcholine at muscarinic receptors, leading to reduced salivation and sweating.
• Ipratropium Bromide HFA Inhalation Aerosol · Pearl Therapeutics, Inc. · Anticholinergic · Respiratory
  Anticholinergic agent that inhibits muscarinic acetylcholine receptors