Anticholinergic agent

This page covers all Anticholinergic agent drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Muscarinic acetylcholine receptor (M1), M3 muscarinic acetylcholine receptor, Muscarinic acetylcholine receptor (M3).

Targets

Muscarinic acetylcholine receptor (M1) · M3 muscarinic acetylcholine receptor · Muscarinic acetylcholine receptor (M3) · Muscarinic acetylcholine receptors (M3) · Muscarinic acetylcholine receptors · Muscarinic acetylcholine receptors (non-selective or subtype-specific) · Muscarinic acetylcholine receptors (M1, M3, M5) · Muscarinic acetylcholine receptor (non-selective antagonist) · Muscarinic acetylcholine receptors (M1-M5) · Muscarinic acetylcholine receptors (M3 subtype)

Marketed (12)

• Transdermal Scopolamine · Repurposed Therapeutics, Inc. · Gastroenterology / Neurology
  Transdermal scopolamine blocks muscarinic acetylcholine receptors to reduce motion sickness and nausea by decreasing vestibular sensitivity and gastric motility.
• Oxybutynin chloride, extended-release · US Department of Veterans Affairs · Urology
  Oxybutynin chloride is an anticholinergic agent that blocks muscarinic acetylcholine receptors in the bladder smooth muscle, reducing involuntary contractions and increasing bladder capacity.
• Oxybutinin Extended-Release · Janssen-Cilag Ltd.,Thailand · Urology
  Oxybutynin is an anticholinergic agent that blocks muscarinic acetylcholine receptors in the bladder smooth muscle, reducing involuntary contractions and increasing bladder capacity.
• Oxybutynin ER · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. · Urology / Neurology
  Oxybutynin is an anticholinergic agent that blocks muscarinic acetylcholine receptors in the bladder smooth muscle, reducing involuntary contractions and increasing bladder capacity.
• Intravenous scopolamine hydrobromide · University of Iowa · Anesthesia and Perioperative Medicine
  Scopolamine is an anticholinergic agent that blocks muscarinic acetylcholine receptors to reduce secretions and motion-induced nausea.
• ACs · GlaxoSmithKline · Multiple (Respiratory, Gastrointestinal, Ophthalmology, Neurology)
  ACs are anticholinergic agents that block acetylcholine receptors to reduce parasympathetic nervous system activity.
• scopolamine transdermal · Stony Brook University · Gastroenterology / Antiemetics
  Scopolamine blocks muscarinic acetylcholine receptors in the central nervous system to prevent nausea and vomiting.
• Transderm Scop® · University of Iowa · Gastroenterology / Anesthesia
  Scopolamine blocks muscarinic acetylcholine receptors to prevent nausea and vomiting by reducing vestibular and chemoreceptor trigger zone activity.
• scopolamine patch · Rutgers, The State University of New Jersey · Gastroenterology / Neurology
  Scopolamine blocks muscarinic acetylcholine receptors in the central nervous system to prevent nausea and vomiting.
• Active B&O suppository of belladonna · Edgar LeClaire, MD · Gastroenterology
  Belladonna alkaloids block muscarinic acetylcholine receptors to reduce smooth muscle contractions and secretions in the gastrointestinal and urinary tracts.
• Trospium Cl · Toronto Rehabilitation Institute · Urology
  Trospium chloride is an anticholinergic agent that blocks muscarinic receptors in the bladder smooth muscle, reducing involuntary contractions and urinary urgency.
• Bencycloquidium Bromide Nasal Spray · Yingu Pharmaceutical Co., Ltd · Respiratory / Allergy
  Bencycloquidium bromide is an anticholinergic agent that blocks muscarinic acetylcholine receptors to reduce nasal secretions and congestion.

Phase 3 pipeline (4)

• scopolamine HBr · Repurposed Therapeutics, Inc. · Neurology / Gastroenterology
  Scopolamine HBr is an anticholinergic agent that blocks muscarinic acetylcholine receptors to reduce secretions and motion-induced nausea.
• OROS® oxybutynin or Ditropan® · Alza Corporation, DE, USA · Urology / Neurology
  Oxybutynin is an anticholinergic agent that blocks muscarinic acetylcholine receptors in the bladder smooth muscle, reducing involuntary contractions and increasing bladder capacity.
• OROS® oxybutynin · Alza Corporation, DE, USA · Urology / Gastroenterology
  OROS oxybutynin is an anticholinergic agent that blocks muscarinic receptors in the bladder smooth muscle, reducing involuntary contractions and increasing bladder capacity.
• Oxybutynin Transdermal Patch · University of California, Davis · Urology / Neurology
  Oxybutynin is an anticholinergic agent that blocks muscarinic acetylcholine receptors in the bladder smooth muscle, reducing involuntary contractions and increasing bladder capacity.