Iron replacement agent

This page covers all Iron replacement agent drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Iron (Fe3+) for hemoglobin and myoglobin synthesis, Transferrin receptor (indirect); iron supplementation, Iron metabolism pathway; transferrin receptor.

Targets

Iron (Fe3+) for hemoglobin and myoglobin synthesis · Transferrin receptor (indirect); iron supplementation · Iron metabolism pathway; transferrin receptor · Iron (Fe3+) / transferrin receptor · Iron (Fe3+) delivery system · Iron (Fe3+) delivery; hemoglobin and myoglobin synthesis · Iron metabolism / transferrin-mediated iron transport · Iron metabolism pathway · Transferrin (iron transport protein) · Iron transporter (DMT1/SLC11A2)

Marketed (14)

• Aggressive iron dextran supplementation · Shanghai East Hospital · Hematology
  Iron dextran is a colloidal iron-carbohydrate complex that replenishes depleted iron stores by providing bioavailable iron for hemoglobin synthesis.
• Intravenous iron sucrose · Ain Shams University · Hematology
  Iron sucrose is a carbohydrate complex that delivers iron directly into the bloodstream to replenish iron stores and support hemoglobin synthesis in patients with iron deficiency.
• Iron Sucrose IV · CN NGANOU-GNINDJIO, MD, MSc · Hematology
  Iron sucrose delivers iron as a stable complex that is absorbed and utilized by the body to replenish iron stores and support hemoglobin synthesis.
• venoferrum(iron sucrose) · JW Pharmaceutical · Hematology
  Iron sucrose provides bioavailable iron to replenish depleted iron stores and support hemoglobin synthesis in patients with iron deficiency anemia.
• Ferric Carboxymaltose Injection · Sichuan Huiyu Pharmaceutical Co., Ltd · Hematology
  Ferric carboxymaltose delivers iron as a stable complex that is taken up by iron-binding proteins to replenish depleted iron stores and restore hemoglobin synthesis.
• i.v. iron sucrose · J. Uriach and Company · Hematology
  Iron sucrose is a stable iron-carbohydrate complex that delivers iron directly into the bloodstream to replenish depleted iron stores and support hemoglobin synthesis.
• Brand sodium ferric gluconate · University of Maryland, Baltimore · Hematology
  Sodium ferric gluconate delivers iron intravenously to replenish iron stores and treat iron deficiency anemia.
• Iron isomaltoside · Thomas Jefferson University · Hematology
  Iron isomaltoside is an iron replacement therapy that delivers ferric iron complexed with isomaltoside, allowing efficient absorption and utilization for hemoglobin synthesis in iron-deficient patients.
• Triferic AVNU · Rockwell Medical Technologies, Inc. · Nephrology / Hematology
  Triferic AVNU is an iron replacement therapy that delivers iron directly into the bloodstream during hemodialysis to treat iron deficiency anemia.
• Generic sodium ferric gluconate · University of Maryland, Baltimore · Hematology
  Sodium ferric gluconate delivers iron directly into the bloodstream to replenish iron stores and treat iron deficiency anemia.
• ferric(III)carboxymaltose · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Hematology
  Ferric carboxymaltose is an iron replacement therapy that delivers ferric iron complexed with carboxymaltose to replenish depleted iron stores and treat iron deficiency anemia.
• Sodium ferric gluconate · University of North Carolina, Chapel Hill · Hematology
  Sodium ferric gluconate is an iron replacement therapy that delivers ferric iron in a stable gluconate complex to replenish depleted iron stores.
• Venofer® · Azad Pharma AG · Hematology
  Venofer® is an iron sucrose complex that replenishes iron stores in patients with iron deficiency anemia, particularly those with chronic kidney disease on hemodialysis.
• High-dose ferric derisomaltose · China-Japan Friendship Hospital · Hematology
  High-dose ferric derisomaltose delivers iron directly to iron-deficient patients via a stable iron-carbohydrate complex that is absorbed and utilized for hemoglobin synthesis.

Phase 3 pipeline (4)

• Ferric Derisomaltose Injection · Hallym University Medical Center · Hematology
  Ferric derisomaltose is an iron replacement therapy that delivers ferric iron complexed with derisomaltose to replenish depleted iron stores.
• Iron Isomaltoside 1000, ferric derisomaltose · Saskatchewan Health Authority - Regina Area · Hematology
  Iron isomaltoside 1000 is an iron-carbohydrate complex that delivers ferric iron to bind transferrin and replenish iron stores in patients with iron deficiency.
• iron isomaltoside(Monofer®) · Prince of Wales Hospital, Shatin, Hong Kong · Hematology
  Iron isomaltoside is an iron carbohydrate complex that delivers iron to iron-deficient patients by binding iron in a stable complex that is taken up by iron-transporting cells.
• iron sucrose injection USP · American Regent, Inc. · Hematology
  Iron sucrose delivers iron directly into the bloodstream as a stable complex to replenish iron stores and support hemoglobin synthesis in patients with iron deficiency.