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Generic sodium ferric gluconate

University of Maryland, Baltimore · FDA-approved active Small molecule

Sodium ferric gluconate delivers iron directly into the bloodstream to replenish iron stores and treat iron deficiency anemia.

Sodium ferric gluconate delivers iron directly into the bloodstream to replenish iron stores and treat iron deficiency anemia. Used for Iron deficiency anemia in patients with chronic kidney disease on hemodialysis, Iron deficiency anemia in patients with non-dialysis chronic kidney disease.

At a glance

Generic nameGeneric sodium ferric gluconate
Also known asgeneric iron
SponsorUniversity of Maryland, Baltimore
Drug classIron replacement agent
TargetIron (Fe3+) delivery; hemoglobin and myoglobin synthesis
ModalitySmall molecule
Therapeutic areaHematology
PhaseFDA-approved

Mechanism of action

The drug is an iron replacement therapy that provides ferric iron complexed with gluconate, allowing rapid intravenous administration without the gastrointestinal side effects of oral iron supplements. The iron is incorporated into hemoglobin and myoglobin, restoring oxygen-carrying capacity in patients with iron deficiency, particularly those with chronic kidney disease on hemodialysis who cannot tolerate or absorb oral iron adequately.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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