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Ferric Derisomaltose Injection
Ferric Derisomaltose Injection is a Iron replacement agent Small molecule drug developed by Hallym University Medical Center. It is currently in Phase 3 development for Iron deficiency anemia in patients with chronic kidney disease, Iron deficiency anemia in patients intolerant to or unresponsive to oral iron therapy. Also known as: iron isomaltoside, Monoferric, Monofer.
Ferric derisomaltose is an iron replacement therapy that delivers ferric iron complexed with derisomaltose to replenish depleted iron stores.
Ferric derisomaltose is an iron replacement therapy that delivers ferric iron complexed with derisomaltose to replenish depleted iron stores. Used for Iron deficiency anemia in patients with chronic kidney disease, Iron deficiency anemia in patients intolerant to or unresponsive to oral iron therapy.
At a glance
| Generic name | Ferric Derisomaltose Injection |
|---|---|
| Also known as | iron isomaltoside, Monoferric, Monofer |
| Sponsor | Hallym University Medical Center |
| Drug class | Iron replacement agent |
| Target | Iron metabolism pathway |
| Modality | Small molecule |
| Therapeutic area | Hematology |
| Phase | Phase 3 |
Mechanism of action
Ferric derisomaltose is a ferric iron carbohydrate complex designed for intravenous administration. The derisomaltose ligand stabilizes the ferric iron and facilitates cellular uptake via transferrin-independent pathways, allowing rapid iron delivery to iron-deficient tissues and bone marrow for hemoglobin synthesis.
Approved indications
- Iron deficiency anemia in patients with chronic kidney disease
- Iron deficiency anemia in patients intolerant to or unresponsive to oral iron therapy
Common side effects
- Injection site reactions
- Headache
- Nausea
- Dizziness
- Hypersensitivity reactions
Key clinical trials
- Post-operative Intravenous Iron to Treat Iron-deficiency Anemia in Patients Undergoing Cardiac Surgery (PHASE2)
- The Effect of Preoperative Intravenous Ferric Derisomaltose and EPO and Tranexamic Acid in Patients With Preoperative Anemia or Iron Deficiency in Bone Tumor (PHASE4)
- Study on Supplement of Intravenous Ferric Derisomaltose to Prevent Anemia and Improve the Quality of Life in Obese Patients With Iron Deficiency. (NA)
- The Effects of Ferric Derisomaltose in Patients With Acute Heart Failure and Iron Deficiency on Exercise Capacity and Quality of Life (PHASE4)
- The Effects of Ferric Derisomaltose in Patients With Acute Heart Failure and Iron Deficiency on Exercise Capacity and Quality of Life(COREVIVE-HFrEF) (PHASE4)
- Accelerated Recovery for Total Knee Replacement Surgery With Preoperative Intravenous Iron Combined With Human Erythropoietin for Rapid Hematopoietic Mobilization to Prevent Postoperative Anemia (NA)
- High Dose IV Iron Plus ESA in Chemotherapy-induced Anemia (PHASE3)
- Ferric Derisomaltose/Iron Isomaltoside and Outcomes in the Recovery of Gynecologic Oncology ERAS (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Ferric Derisomaltose Injection CI brief — competitive landscape report
- Ferric Derisomaltose Injection updates RSS · CI watch RSS
- Hallym University Medical Center portfolio CI
Frequently asked questions about Ferric Derisomaltose Injection
What is Ferric Derisomaltose Injection?
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Related
- Drug class: All Iron replacement agent drugs
- Target: All drugs targeting Iron metabolism pathway
- Manufacturer: Hallym University Medical Center — full pipeline
- Therapeutic area: All drugs in Hematology
- Indication: Drugs for Iron deficiency anemia in patients with chronic kidney disease
- Indication: Drugs for Iron deficiency anemia in patients intolerant to or unresponsive to oral iron therapy
- Also known as: iron isomaltoside, Monoferric, Monofer
- Compare: Ferric Derisomaltose Injection vs similar drugs
- Pricing: Ferric Derisomaltose Injection cost, discount & access