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venoferrum(iron sucrose)
Iron sucrose provides bioavailable iron to replenish depleted iron stores and support hemoglobin synthesis in patients with iron deficiency anemia.
Iron sucrose provides bioavailable iron to replenish depleted iron stores and support hemoglobin synthesis in patients with iron deficiency anemia. Used for Iron deficiency anemia in patients with chronic kidney disease on hemodialysis, Iron deficiency anemia in patients with chronic kidney disease not on dialysis, Iron deficiency anemia in patients receiving erythropoiesis-stimulating agents.
At a glance
| Generic name | venoferrum(iron sucrose) |
|---|---|
| Sponsor | JW Pharmaceutical |
| Drug class | Iron replacement agent |
| Modality | Small molecule |
| Therapeutic area | Hematology |
| Phase | FDA-approved |
Mechanism of action
Iron sucrose is a complex of iron(III) hydroxide with sucrose that delivers iron intravenously. The iron is released and incorporated into hemoglobin and myoglobin, restoring oxygen-carrying capacity. This formulation is designed for patients who cannot tolerate or absorb oral iron, particularly those with chronic kidney disease on hemodialysis.
Approved indications
- Iron deficiency anemia in patients with chronic kidney disease on hemodialysis
- Iron deficiency anemia in patients with chronic kidney disease not on dialysis
- Iron deficiency anemia in patients receiving erythropoiesis-stimulating agents
Common side effects
- Hypotension
- Nausea
- Vomiting
- Abdominal pain
- Headache
- Diarrhea
- Injection site reactions
Key clinical trials
- Perioperative Iron With Erythropoietin in Bilateral Total Knee Replacement Arthroplasty (TKRA) (NA)
- Efficacy and Safety Study of Iron Sucrose and Oral Iron Acetyl-transferrin Hydroglycerin (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- venoferrum(iron sucrose) CI brief — competitive landscape report
- venoferrum(iron sucrose) updates RSS · CI watch RSS
- JW Pharmaceutical portfolio CI