{"id":"venoferrum-iron-sucrose","safety":{"commonSideEffects":[{"rate":"5-10","effect":"Hypotension"},{"rate":"5-10","effect":"Nausea"},{"rate":"3-7","effect":"Vomiting"},{"rate":"3-7","effect":"Abdominal pain"},{"rate":"3-7","effect":"Headache"},{"rate":"2-5","effect":"Diarrhea"},{"rate":"1-3","effect":"Injection site reactions"}]},"_chembl":{"chemblId":"CHEMBL1200823","moleculeType":"Small molecule","molecularWeight":"398.14"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Iron sucrose is a complex of iron(III) hydroxide with sucrose that delivers iron intravenously. The iron is released and incorporated into hemoglobin and myoglobin, restoring oxygen-carrying capacity. This formulation is designed for patients who cannot tolerate or absorb oral iron, particularly those with chronic kidney disease on hemodialysis.","oneSentence":"Iron sucrose provides bioavailable iron to replenish depleted iron stores and support hemoglobin synthesis in patients with iron deficiency anemia.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:15:02.252Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Iron deficiency anemia in patients with chronic kidney disease on hemodialysis"},{"name":"Iron deficiency anemia in patients with chronic kidney disease not on dialysis"},{"name":"Iron deficiency anemia in patients receiving erythropoiesis-stimulating agents"}]},"trialDetails":[{"nctId":"NCT01012063","phase":"NA","title":"Perioperative Iron With Erythropoietin in Bilateral Total Knee Replacement Arthroplasty (TKRA)","status":"COMPLETED","sponsor":"Seoul National University Bundang Hospital","startDate":"2008-08","conditions":"Anemia, Transfusion","enrollment":54},{"nctId":"NCT00802139","phase":"PHASE4","title":"Efficacy and Safety Study of Iron Sucrose and Oral Iron Acetyl-transferrin Hydroglycerin","status":"COMPLETED","sponsor":"JW Pharmaceutical","startDate":"2008-02","conditions":"Iron Deficiency Anemia","enrollment":58}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"venoferrum(iron sucrose)","genericName":"venoferrum(iron sucrose)","companyName":"JW Pharmaceutical","companyId":"jw-pharmaceutical","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Iron sucrose provides bioavailable iron to replenish depleted iron stores and support hemoglobin synthesis in patients with iron deficiency anemia. Used for Iron deficiency anemia in patients with chronic kidney disease on hemodialysis, Iron deficiency anemia in patients with chronic kidney disease not on dialysis, Iron deficiency anemia in patients receiving erythropoiesis-stimulating agents.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}