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Triferic AVNU
Triferic AVNU is an iron replacement therapy that delivers iron directly into the bloodstream during hemodialysis to treat iron deficiency anemia.
Triferic AVNU is an iron replacement therapy that delivers iron directly into the bloodstream during hemodialysis to treat iron deficiency anemia. Used for Iron deficiency anemia in patients with chronic kidney disease on hemodialysis.
At a glance
| Generic name | Triferic AVNU |
|---|---|
| Also known as | Ferric Pyrophosphate Citrate (FPC), FPC |
| Sponsor | Rockwell Medical Technologies, Inc. |
| Drug class | Iron replacement agent |
| Target | Iron (Fe3+) delivery system |
| Modality | Small molecule |
| Therapeutic area | Nephrology / Hematology |
| Phase | FDA-approved |
Mechanism of action
Triferic AVNU (ferric pyrophosphate citrate) is administered intravenously during hemodialysis sessions and replaces iron lost during dialysis and due to chronic kidney disease-related blood loss. It works by providing bioavailable iron that is incorporated into hemoglobin and myoglobin, thereby correcting iron deficiency anemia in patients with chronic kidney disease on hemodialysis without requiring separate iron infusions.
Approved indications
- Iron deficiency anemia in patients with chronic kidney disease on hemodialysis
Common side effects
- Hypophosphatemia
- Hyperkalemia
- Hypertension
- Vascular access complications
Key clinical trials
- Triferic AVNU Infusion Via Freedom Pump During Hemodialysis (PHASE4)
- Treatment of (IDA) by (FPC) Delivered Via Infusion Pump in Patients Receiving Home Infusion Therapy (PHASE2)
- Study to Investigate the Pharmacokinetic Comparability of Dosing Triferic AVNU IV by Continuous Infusion and IV Bolus. (PHASE1, PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Triferic AVNU CI brief — competitive landscape report
- Triferic AVNU updates RSS · CI watch RSS
- Rockwell Medical Technologies, Inc. portfolio CI