What are Combination vaccine drugs?

Combination vaccine drugs are pharmacologic agents that share a common mechanism (typically targeting Hepatitis A virus antigen; Hepatitis B surface antigen (HBsAg)). 16 are currently marketed, with 45 more in clinical development.

What are the marketed Combination vaccine drugs?

Marketed Combination vaccine drugs include 23vPPV+TIV, BoostrixTM Polio, Boostrix IPV infant whole Pertussis, Boostrix ® Polio, hepatitis A vaccine, DTaP, PCV10, Infanrix IPV.

Combination vaccine

16 marketed 45 in Phase 3

This page covers all Combination vaccine drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Hepatitis A virus antigen; Hepatitis B surface antigen (HBsAg), Hepatitis B surface antigen; Haemophilus influenzae type b polysaccharide.

Targets

Hepatitis A virus antigen; Hepatitis B surface antigen (HBsAg) · Hepatitis B surface antigen; Haemophilus influenzae type b polysaccharide

Marketed (16)

23vPPV+TIV · Jiangsu Province Centers for Disease Control and Prevention · Immunology / Infectious Disease
A combined pneumococcal and influenza vaccine that stimulates immune responses against 23 serotypes of Streptococcus pneumoniae and seasonal influenza virus strains.
BoostrixTM Polio · GlaxoSmithKline · Immunology / Infectious Disease
Boostrix Polio is a combination vaccine that stimulates the immune system to produce antibodies against diphtheria, tetanus, pertussis, and poliovirus.
Boostrix IPV infant whole Pertussis · London School of Hygiene and Tropical Medicine · Immunology / Infectious Disease
This combination vaccine stimulates the immune system to produce antibodies and cellular immunity against diphtheria, tetanus, pertussis, and poliomyelitis.
Boostrix ® Polio · GlaxoSmithKline · Immunology
Boostrix Polio is a combination vaccine that stimulates the immune system to produce antibodies against diphtheria, tetanus, pertussis, and poliovirus.
hepatitis A vaccine, DTaP, PCV10 · KEMRI-Wellcome Trust Collaborative Research Program · Immunology
This is a combination vaccine that stimulates the immune system to produce antibodies against hepatitis A virus, diphtheria, tetanus, pertussis, and pneumococcal pathogens.
Infanrix IPV · GlaxoSmithKline · Immunology
Infanrix IPV is a combination vaccine that stimulates the immune system to produce antibodies against diphtheria, tetanus, pertussis, and inactivated poliovirus.
Infanrix® Penta · GlaxoSmithKline · Immunology / Infectious Disease Prevention
Infanrix Penta is a combination vaccine that stimulates the immune system to produce antibodies against diphtheria, tetanus, pertussis, poliomyelitis, and Haemophilus influenzae type b.
H-VA dual therapy · The First Affiliated Hospital of Nanchang University · Immunology / Infectious Disease
H-VA dual therapy combines hepatitis B virus (HBV) and hepatitis A virus (HAV) immunization in a single formulation to provide dual protection against both viral infections.
TDaP-IPV vaccine · Radboud University Medical Center · Immunology
TDaP-IPV is a combination vaccine that stimulates the immune system to produce antibodies against tetanus, diphtheria, pertussis, and poliovirus.
Infanrix-IPV/Hib · GlaxoSmithKline · Immunology
Infanrix-IPV/Hib is a combination vaccine that stimulates the immune system to produce antibodies against diphtheria, tetanus, pertussis, poliomyelitis, and Haemophilus influenzae type b.
Boostrix®-IPV combination vaccine · University of Oxford · Immunology
Boostrix-IPV is a combination vaccine that stimulates the immune system to produce antibodies against diphtheria, tetanus, pertussis, and poliovirus.
Healive+Healive · Sinovac Biotech Co., Ltd · Immunology / Infectious Disease
Healive+Healive is a hepatitis A and hepatitis B combination vaccine that stimulates the immune system to produce antibodies against both hepatitis A and B viruses.
sIPV+DTaP+MMR · China National Biotec Group Company Limited · Immunology / Infectious Disease Prevention
This combination vaccine provides immunization against poliomyelitis, diphtheria, tetanus, pertussis, measles, mumps, and rubella through inactivated viral and bacterial antigens.
sIPV+DTaP+HepA · China National Biotec Group Company Limited · Immunology / Infectious Disease Prevention
This combination vaccine provides immunization against poliomyelitis, diphtheria, tetanus, pertussis, and hepatitis A through inactivated viral and bacterial antigens.
Pentacel (DPTaP+Hib) · The Hospital for Sick Children · Immunology
Pentacel is a combination vaccine that stimulates the immune system to produce antibodies against diphtheria, pertussis, tetanus, and Haemophilus influenzae type b (Hib) bacteria.
Pediacel® · MCM Vaccines B.V. · Immunology / Infectious Disease Prevention
Pediacel is a combination vaccine that stimulates the immune system to produce antibodies against diphtheria, tetanus, pertussis, poliomyelitis, and Haemophilus influenzae type b.

Phase 3 pipeline (45)

DTaP-IPV vero vaccine · Statens Serum Institut · Immunology
This vaccine stimulates the immune system to produce antibodies and cellular immunity against diphtheria, tetanus, pertussis, and poliovirus by presenting inactivated antigens.
DT3aP-HBs-IPV · Sanofi Pasteur, a Sanofi Company · Immunology / Infectious Disease
DT3aP-HBs-IPV is a combination vaccine that provides immunization against diphtheria, tetanus, pertussis, hepatitis B, and poliomyelitis through simultaneous administration of multiple antigens.
DTacP-IPV/Hib · Changchun BCHT Biotechnology Co. · Immunology / Infectious Disease Prevention
DTacP-IPV/Hib is a combination vaccine that provides immunization against diphtheria, tetanus, acellular pertussis, poliomyelitis, and Haemophilus influenzae type b through inactivated antigens and toxoids.
DTaP-IPV-Hep B-PRP~T combined vaccine · Sanofi Pasteur, a Sanofi Company · Immunology / Infectious Disease Prevention
This combined vaccine stimulates the immune system to produce antibodies and cellular immunity against diphtheria, tetanus, pertussis, poliomyelitis, hepatitis B, and Haemophilus influenzae type b.
InfanrixTM IPV/Hib · GlaxoSmithKline · Immunology
Infanrix IPV/Hib is a combination vaccine that stimulates the immune system to produce antibodies against diphtheria, tetanus, pertussis, poliomyelitis, and Haemophilus influenzae type b.
Tritanrix/Hiberix vaccine · GlaxoSmithKline · Immunology
Tritanrix/Hiberix is a combination vaccine that provides immunization against diphtheria, tetanus, pertussis, and Haemophilus influenzae type b through inactivated toxoids and conjugate antigens.
Recombinant Hepatitis B + DTP-HB-Hib · PT Bio Farma · Immunology / Infectious Disease
This combination vaccine provides immunization against hepatitis B, diphtheria, tetanus, pertussis, and Haemophilus influenzae type b by stimulating the immune system to produce protective antibodies against these pathogens.
DTaP-IPV mkc vaccine · Statens Serum Institut · Immunology
DTaP-IPV mkc vaccine stimulates the immune system to produce antibodies and cellular immunity against diphtheria, tetanus, pertussis, and poliovirus through inactivated antigens.
DTaP-IPV/Hib Combined vaccine · Sanofi Pasteur, a Sanofi Company · Immunology
This combined vaccine stimulates the immune system to produce antibodies and cellular immunity against diphtheria, tetanus, pertussis, poliomyelitis, and Haemophilus influenzae type b.
InfanrixTM IPV · GlaxoSmithKline · Immunology / Infectious Disease
Infanrix IPV is a combination vaccine that stimulates the immune system to produce antibodies against diphtheria, tetanus, pertussis, and poliovirus.
DPT-IPV · Tanabe Pharma Corporation · Immunology / Infectious Disease
DPT-IPV is a combination vaccine that provides immunization against diphtheria, pertussis, tetanus, and inactivated poliovirus.
DPT-IPV-Hib · Tanabe Pharma Corporation · Immunology / Infectious Disease Prevention
DPT-IPV-Hib is a combination vaccine that provides immunization against diphtheria, pertussis, tetanus, poliomyelitis, and Haemophilus influenzae type b through inactivated pathogen antigens and toxoids.
DTaP-IPV//PRP~T and Hepatitis B vaccine · Sanofi Pasteur, a Sanofi Company · Immunology / Infectious Disease Prevention
This combination vaccine stimulates the immune system to produce antibodies against diphtheria, tetanus, pertussis, poliomyelitis, Haemophilus influenzae type b, and hepatitis B.
DTaP-IPV//PRP~T combined · Sanofi Pasteur, a Sanofi Company · Immunology / Infectious Disease Prevention
This combined vaccine stimulates the immune system to produce antibodies and cellular immunity against diphtheria, tetanus, pertussis, poliomyelitis, and Haemophilus influenzae type b.
ActHIB+ DPT-TAKEDA · Takeda · Immunology / Infectious Disease
ActHIB+ DPT-TAKEDA is a combined vaccine that provides immunization against Haemophilus influenzae type b, diphtheria, pertussis, and tetanus through active immunization.
GSK Biologicals'Kinrix® · GlaxoSmithKline · Immunology / Infectious Disease Prevention
Kinrix is a combination vaccine that provides immunization against diphtheria, tetanus, pertussis, poliomyelitis, and hepatitis B by stimulating the immune system to produce protective antibodies against these pathogens.
DTaP-IPV combination vaccine · Boryung Biopharma Co., Ltd. · Immunology
This combination vaccine stimulates the immune system to produce antibodies and cellular immunity against diphtheria, tetanus, pertussis, and poliovirus by delivering inactivated toxins and viral antigens.
Hib-MenAC mixed with Tritanrix™-HepB · GlaxoSmithKline · Immunology / Infectious Disease
This combination vaccine stimulates immune responses against Haemophilus influenzae type b, Neisseria meningitidis serogroups A and C, diphtheria, tetanus, pertussis, hepatitis B, and poliomyelitis through antigen presentation.
Comparator: Adacel™ · Merck Sharp & Dohme LLC · Immunology / Infectious Disease
Adacel is a combination vaccine that stimulates the immune system to produce antibodies against diphtheria, tetanus, pertussis (whooping cough), and poliomyelitis.
DT-Polio® · Sanofi Pasteur, a Sanofi Company · Immunology / Infectious Disease
DT-Polio is a combined diphtheria-tetanus-poliomyelitis vaccine that stimulates the immune system to produce antibodies against diphtheria toxin, tetanus toxin, and poliovirus.
BRV-PV Lot A + DPT-HepB-Hib + OPV · Serum Institute of India Pvt. Ltd. · Immunology / Infectious Disease Prevention
This is a combination vaccine that provides immunization against rotavirus, diphtheria, pertussis, tetanus, hepatitis B, Haemophilus influenzae type b, and poliomyelitis through simultaneous administration of inactivated and live attenuated viral/bacterial antigens.
Triple Antigen™ · GlaxoSmithKline · Immunology / Infectious Disease
Triple Antigen™ is a vaccine that stimulates immune responses against three disease antigens simultaneously to provide combined protection.
Tritanrix™-HepB Kft · GlaxoSmithKline · Immunology / Infectious Disease
Tritanrix-HepB is a combination vaccine that provides immunization against diphtheria, tetanus, pertussis, and hepatitis B through simultaneous administration of inactivated toxoids and recombinant hepatitis B surface antigen.
Pediarix TM, Infanrix penta TM · GlaxoSmithKline · Immunology / Infectious Disease Prevention
Pediarix and Infanrix penta are combination vaccines that stimulate the immune system to produce antibodies against diphtheria, tetanus, pertussis, poliomyelitis, and hepatitis B through inactivated antigens.
DTPa-HBV-IPV (Infanrix penta™) · GlaxoSmithKline · Immunology / Infectious Disease Prevention
DTPa-HBV-IPV is a combination vaccine that stimulates the immune system to produce antibodies against diphtheria, tetanus, pertussis, hepatitis B, and poliomyelitis.
Boostrix PolioTM · GlaxoSmithKline · Immunology
Boostrix Polio is a combination vaccine that stimulates the immune system to produce antibodies against diphtheria, tetanus, pertussis, and poliovirus.
BRV-PV Lot C + DPT-HepB-Hib + OPV · Serum Institute of India Pvt. Ltd. · Immunology / Infectious Disease Prevention
This is a combination vaccine that provides immunization against rotavirus (BRV-PV), diphtheria, pertussis, tetanus, hepatitis B, Haemophilus influenzae type b, and poliomyelitis through active immune stimulation.
BRV-PV Lot B + DPT-HepB-Hib + OPV · Serum Institute of India Pvt. Ltd. · Immunology / Infectious Disease Prevention
This is a combination vaccine that provides immunization against rotavirus (BRV-PV), diphtheria, pertussis, tetanus, hepatitis B, Haemophilus influenzae type b, and poliomyelitis through inactivated and live attenuated viral/bacterial antigens.
TritanrixHepB/Hib · GlaxoSmithKline · Immunology / Infectious Disease
TritanrixHepB/Hib is a combination vaccine that stimulates the immune system to produce antibodies against diphtheria, tetanus, pertussis, hepatitis B, and Haemophilus influenzae type b.
DTaP-IPV combined vaccine · Sanofi · Immunology / Infectious Disease Prevention
This combined vaccine stimulates the immune system to produce antibodies and cellular immunity against diphtheria, tetanus, pertussis, and poliovirus by delivering inactivated toxins and viral antigens.
DTPa-IPV · GlaxoSmithKline · Immunology / Infectious Disease Prevention
DTPa-IPV is a combination vaccine that stimulates the immune system to produce antibodies against diphtheria, tetanus, pertussis, and poliovirus.
DTPw-HBV/Hib · GlaxoSmithKline · Immunology / Infectious Disease Prevention
DTPw-HBV/Hib is a combination vaccine that stimulates the immune system to produce antibodies against diphtheria, tetanus, pertussis, hepatitis B, and Haemophilus influenzae type b.
Boostrix Polio™ 711866 · GlaxoSmithKline · Immunology / Infectious Disease
Boostrix Polio is a combined vaccine that stimulates the immune system to produce antibodies against diphtheria, tetanus, pertussis, and poliovirus.
DTPw-HBV/Hib Kft vaccine GSK323527A · GlaxoSmithKline · Immunology / Infectious Disease Prevention
This combination vaccine stimulates immune responses against diphtheria, tetanus, pertussis, hepatitis B, and Haemophilus influenzae type b through inactivated antigens and recombinant proteins.
Comparator: Comvax · Merck Sharp & Dohme LLC · Immunology / Infectious Disease
Comvax is a combination vaccine that provides immunization against hepatitis B virus and Haemophilus influenzae type b (Hib) by stimulating the immune system to produce protective antibodies against both pathogens.
Comparator: Infanrix(tm) Hexa · Merck Sharp & Dohme LLC · Immunology / Infectious Disease Prevention
Infanrix Hexa is a combination vaccine that stimulates the immune system to produce antibodies against six infectious diseases by presenting inactivated or toxoid antigens.
Vaxelis vaccine · Sanofi · Immunology
Vaxelis is a combination vaccine that stimulates the immune system to produce antibodies and cellular immunity against multiple infectious diseases simultaneously.
InfanrixTM hexa · GlaxoSmithKline · Immunology / Infectious Disease Prevention
Infanrix hexa is a combination vaccine that stimulates the immune system to produce antibodies against six infectious diseases by presenting inactivated or toxoid antigens.
Tritanrix-HepB/Hib™ · Sanofi Pasteur, a Sanofi Company · Immunology
Tritanrix-HepB/Hib is a combination vaccine that stimulates the immune system to produce antibodies against diphtheria, tetanus, pertussis, hepatitis B, and Haemophilus influenzae type b.
Hep B + Pentabio (registered) · PT Bio Farma · Immunology / Infectious Disease Prevention
Hep B + Pentabio is a combination vaccine that provides immunization against hepatitis B and five other infectious diseases (diphtheria, tetanus, pertussis, poliomyelitis, and Haemophilus influenzae type b) by stimulating adaptive immune responses.