Last reviewed · How we verify
Vaxelis vaccine
Vaxelis vaccine is a Combination vaccine Biologic drug developed by Sanofi. It is currently in Phase 3 development for Active immunization against diphtheria, tetanus, pertussis, poliomyelitis, hepatitis B, Haemophilus influenzae type b, meningococcal disease (serogroup C), measles, mumps, rubella, and varicella in infants and children. Also known as: Vaxelis™, Vaxelis®.
Vaxelis is a combination vaccine that stimulates the immune system to produce antibodies and cellular immunity against multiple infectious diseases simultaneously.
Vaxelis is a combination vaccine that stimulates the immune system to produce antibodies and cellular immunity against multiple infectious diseases simultaneously. Used for Active immunization against diphtheria, tetanus, pertussis, poliomyelitis, hepatitis B, Haemophilus influenzae type b, meningococcal disease (serogroup C), measles, mumps, rubella, and varicella in infants and children.
At a glance
| Generic name | Vaxelis vaccine |
|---|---|
| Also known as | Vaxelis™, Vaxelis® |
| Sponsor | Sanofi |
| Drug class | Combination vaccine |
| Modality | Biologic |
| Therapeutic area | Immunology |
| Phase | Phase 3 |
Mechanism of action
Vaxelis combines antigens from 11 different pathogens (diphtheria, tetanus, pertussis, poliomyelitis, hepatitis B, Haemophilus influenzae type b, meningococcal serogroup C, measles, mumps, rubella, and varicella) in a single injection. It works by presenting these antigens to the immune system, triggering both humoral (antibody) and cell-mediated immune responses to provide protection against these diseases.
Approved indications
- Active immunization against diphtheria, tetanus, pertussis, poliomyelitis, hepatitis B, Haemophilus influenzae type b, meningococcal disease (serogroup C), measles, mumps, rubella, and varicella in infants and children
Common side effects
- Injection site reactions (pain, redness, swelling)
- Fever
- Irritability
- Drowsiness
- Loss of appetite
Key clinical trials
- Study of the Safety of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From Approximately 2 Months of Age (PHASE3)
- Lot-to-lot Consistency Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From 2 Months of Age (PHASE3)
- Study of a 4-Dose Regimen of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From Approximately 2 Months of Age (PHASE3)
- Study of Mixed Vaccination Schedules With a 21-valent Pneumococcal Conjugate Vaccine and a 20-valent Pneumococcal Conjugate Vaccine in Healthy Infants From Approximately 2 Months of Age (PHASE3)
- Co-administration Study of an Investigational Live-Attenuated Respiratory Syncytial Virus Vaccine in Infants and Toddlers (PHASE3)
- Safety and Immunogenicity of an Investigational Pentavalent Meningococcal ABCYW Vaccine Against Meningococcal Disease in Children, Toddlers, and Infants (PHASE1, PHASE2)
- Maternal Determinants of Infant Immunity to Pertussis (PHASE4)
- A Study to Evaluate Immunogenicity and Safety of GlaxoSmithKline (GSK)'s Infanrix Hexa Vaccine (DTPa-HBV-IPV/Hib) Versus MCM Vaccine BV's Vaxelis Vaccine (DTaP5-HBV-IPV-Hib) in Healthy Infants and Toddlers (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Vaxelis vaccine CI brief — competitive landscape report
- Vaxelis vaccine updates RSS · CI watch RSS
- Sanofi portfolio CI
Frequently asked questions about Vaxelis vaccine
What is Vaxelis vaccine?
How does Vaxelis vaccine work?
What is Vaxelis vaccine used for?
Who makes Vaxelis vaccine?
Is Vaxelis vaccine also known as anything else?
What drug class is Vaxelis vaccine in?
What development phase is Vaxelis vaccine in?
What are the side effects of Vaxelis vaccine?
Related
- Drug class: All Combination vaccine drugs
- Manufacturer: Sanofi — full pipeline
- Therapeutic area: All drugs in Immunology
- Indication: Drugs for Active immunization against diphtheria, tetanus, pertussis, poliomyelitis, hepatitis B, Haemophilus influenzae type b, meningococcal disease (serogroup C), measles, mumps, rubella, and varicella in infants and children
- Also known as: Vaxelis™, Vaxelis®
- Compare: Vaxelis vaccine vs similar drugs
- Pricing: Vaxelis vaccine cost, discount & access