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DTaP-IPV combined vaccine
DTaP-IPV combined vaccine is a Combination vaccine Biologic drug developed by Sanofi. It is currently in Phase 3 development for Prevention of diphtheria in infants and children, Prevention of tetanus in infants and children, Prevention of pertussis (whooping cough) in infants and children. Also known as: TETRAXIM™: Diphtheria, Tetanus, Polio, Acellular Pertussis.
This combined vaccine stimulates the immune system to produce antibodies and cellular immunity against diphtheria, tetanus, pertussis, and poliovirus by delivering inactivated toxins and viral antigens.
This combined vaccine stimulates the immune system to produce antibodies and cellular immunity against diphtheria, tetanus, pertussis, and poliovirus by delivering inactivated toxins and viral antigens. Used for Prevention of diphtheria in infants and children, Prevention of tetanus in infants and children, Prevention of pertussis (whooping cough) in infants and children.
At a glance
| Generic name | DTaP-IPV combined vaccine |
|---|---|
| Also known as | TETRAXIM™: Diphtheria, Tetanus, Polio, Acellular Pertussis |
| Sponsor | Sanofi |
| Drug class | Combination vaccine |
| Modality | Biologic |
| Therapeutic area | Immunology / Infectious Disease Prevention |
| Phase | Phase 3 |
Mechanism of action
DTaP-IPV is a combination immunization that contains diphtheria and tetanus toxoids (inactivated bacterial toxins), acellular pertussis antigen, and inactivated poliovirus particles. Upon administration, these antigens trigger both humoral (antibody) and cell-mediated immune responses, priming the immune system to recognize and neutralize these pathogens if encountered naturally. This provides protection against four serious infectious diseases in a single vaccine formulation.
Approved indications
- Prevention of diphtheria in infants and children
- Prevention of tetanus in infants and children
- Prevention of pertussis (whooping cough) in infants and children
- Prevention of poliomyelitis in infants and children
Common side effects
- Injection site pain, redness, or swelling
- Fever
- Irritability or fussiness
- Drowsiness
- Loss of appetite
Key clinical trials
- Post-marketing Surveillance Study for the Safety of a DTaP-IPV- HB-PRP~T Vaccine in Republic of Korea
- Study of a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Given With Routine Pediatric Vaccines in Healthy Infants and Toddlers in India and the Republic of South Africa (PHASE3)
- Immunogenicity of a Combined Diphtheria-Tetanus-recombinant Acellular Pertussis (DTaP) Vaccine in Healthy Toddlers (PHASE2, PHASE3)
- Study of a Pneumococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Toddlers and Infants (PHASE2)
- Adsorption of Cell-free Diphtheria and Tetanus (Three-component) Combined With Vaccine Phase III Clinical Trial (PHASE3)
- Study of Concomitant Administration of the sIPV and DTaP or MMR (PHASE4)
- A Clinical Trial of Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed(DTcP) (PHASE3)
- Immunogenicity and Safety Study of a Quadrivalent Meningococcal Conjugate Vaccine When Co-administered With Routine Pediatric Vaccines in Healthy Infants and Toddlers in Europe (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- DTaP-IPV combined vaccine CI brief — competitive landscape report
- DTaP-IPV combined vaccine updates RSS · CI watch RSS
- Sanofi portfolio CI
Frequently asked questions about DTaP-IPV combined vaccine
What is DTaP-IPV combined vaccine?
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What is DTaP-IPV combined vaccine used for?
Who makes DTaP-IPV combined vaccine?
Is DTaP-IPV combined vaccine also known as anything else?
What drug class is DTaP-IPV combined vaccine in?
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Related
- Drug class: All Combination vaccine drugs
- Manufacturer: Sanofi — full pipeline
- Therapeutic area: All drugs in Immunology / Infectious Disease Prevention
- Indication: Drugs for Prevention of diphtheria in infants and children
- Indication: Drugs for Prevention of tetanus in infants and children
- Indication: Drugs for Prevention of pertussis (whooping cough) in infants and children
- Also known as: TETRAXIM™: Diphtheria, Tetanus, Polio, Acellular Pertussis
- Compare: DTaP-IPV combined vaccine vs similar drugs
- Pricing: DTaP-IPV combined vaccine cost, discount & access