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BRV-PV Lot C + DPT-HepB-Hib + OPV
This is a combination vaccine that provides immunization against rotavirus (BRV-PV), diphtheria, pertussis, tetanus, hepatitis B, Haemophilus influenzae type b, and poliomyelitis through active immune stimulation.
This is a combination vaccine that provides immunization against rotavirus (BRV-PV), diphtheria, pertussis, tetanus, hepatitis B, Haemophilus influenzae type b, and poliomyelitis through active immune stimulation. Used for Prevention of rotavirus gastroenteritis in infants, Prevention of diphtheria, pertussis, and tetanus, Prevention of hepatitis B infection.
At a glance
| Generic name | BRV-PV Lot C + DPT-HepB-Hib + OPV |
|---|---|
| Sponsor | Serum Institute of India Pvt. Ltd. |
| Drug class | Combination vaccine |
| Modality | Biologic |
| Therapeutic area | Immunology / Infectious Disease Prevention |
| Phase | Phase 3 |
Mechanism of action
BRV-PV (Rotavirus vaccine) stimulates immune response against rotavirus antigens to prevent rotavirus gastroenteritis. The DPT-HepB-Hib component provides immunization against diphtheria toxoid, pertussis antigens, tetanus toxoid, hepatitis B surface antigen, and Haemophilus influenzae type b polysaccharide conjugate. OPV (Oral Polio Vaccine) contains live attenuated poliovirus strains that induce mucosal and systemic immunity against poliovirus types 1, 2, and 3.
Approved indications
- Prevention of rotavirus gastroenteritis in infants
- Prevention of diphtheria, pertussis, and tetanus
- Prevention of hepatitis B infection
- Prevention of Haemophilus influenzae type b infection
- Prevention of poliomyelitis
Common side effects
- Fever
- Local injection site reactions (pain, swelling, erythema)
- Irritability
- Diarrhea
- Vomiting
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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